Hematology

Latest AI and machine learning research in hematology for healthcare professionals.

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Delineating Pediatric Adrenocortical Tumors by GC-MS Urinary Steroid Metabolome Analysis: Observations From the MET Study.

INTRODUCTION: Adrenocortical tumors (ACTs) comprise adrenocortical adenomas (ACAs) and adrenocortical carcinomas (ACCs); the latter are highly aggressive. Pediatric adrenocortical tumors (pACTs) are functional and thus symptomatic. We investigated whether gas chromatography-mass spectrometry (GC-MS) urinary steroid metabolome analysis can detect tumors and differentiate between adenomas and carcino...

Apr 22 2026 41225718

Analysis and validation of diagnostic biomarkers and immune cell infiltration characteristics in chronic spontaneous urticaria and autophagy based on machine learning.

BACKGROUND: The exact molecular mechanisms governing a heightened risk of chronic spontaneous urticaria (CSU) associated with autophagy remain largely unexplored. METHODS: We used the GSE72540 RNA dataset (human biopsy samples) for CSU as our training set, with GSE57178 (human biopsy samples) and GSE72541(human serum samples)as validation sets. We analyzed differentially expressed autophagy-relate...

Apr 21 2026 42058160
APSevLM: Acute Pancreatitis Severity Language Model.

Approximately one-fifth of patients with acute pancreatitis (AP) develop severe forms, which are associated with high mortality rates, making early pr...

Apr 21 2026 42013267
Diagnosis of Leukemia from Bone Marrow Flow Cytometry Data Using Deep Learning and Explainable Artificial Intelligence.

Leukemia is a life-threatening blood cancer requiring rapid and accurate diagnosis to improve patient survival. Although flow cytometry offers powerfu...

Apr 20 2026 42019815
Clinical utility of BOLD-MRI in accurate diagnosis and prognostic evaluation of diabetic nephropathy: a prospective renal biopsy-based cohort study.

OBJECTIVES: To validate blood oxygen level-dependent MRI (BOLD-MRI) for non-invasive discrimination of diabetic nephropathy (DN) vs non-diabetic renal...

Apr 20 2026 42008071
Visit-to-visit systolic blood pressure variability and risk of severe hypertensive episodes in a multicenter cohort.

BACKGROUND: Visit-to-visit blood pressure variability has been associated with cardiovascular outcomes; however, its role in predicting severe blood p...

Apr 20 2026 42011096
Unveiling novel biomarkers for diabetes-related complications through large-scale proteomics analysis: A FIELD sub-study.

BACKGROUND: Vascular complications of Type 2 diabetes (T2D) significantly contribute to its morbidity and mortality. Identifying robust biomarkers is ...

Apr 19 2026 42019187
Single-cell sequencing and machine learning-based prediction of spliceosome-associated factor 2 may represent potential targets for osteoarthritis.

BACKGROUND: Osteoarthritis has become a global health challenge due to its complex pathologic mechanisms. Spliceosome-associated factor 2 (SYF2) has b...

Apr 18 2026 42094020
Neural network reveals platelet age from fluorescence microscopy images.

Platelets are small, anucleate cells with a primary physiological role in vascular damage repair (hemostasis) and initiation of thrombus formation in ...

Apr 17 2026 41992909
Decoding perioperative anesthesia-associated signature in Kawasaki disease patients with deep vein thrombosis; evidence from machine-learning driven multi-omics.

UNLABELLED: Inappropriate perioperative anesthesia (PA) drug management may lead to the detrimental clinical outcomes of Kawasaki disease (KD) patient...

Apr 17 2026 42006451
Incorporating artificial intelligence into morphological diagnosis of acute leukemias: Current landscape, challenges and prospects (Review).

Acute leukemias (ALs) are a diverse group of hematological malignancies characterized by the abnormal proliferation of immature cells. Microscopic obs...

Apr 17 2026 41992971
Indispensable tools of critical care management: blood gas analyzers.

Blood gas analysis remains one of the most indispensable diagnostic tools in critical care, yet increasing automation often obscures its analytical fo...

Apr 17 2026 41992964
Artificial Intelligence in Trauma Care: A Systematic Review of Resuscitation, Diagnosis, Risk Prediction, and Management.

BACKGROUND: Artificial intelligence (AI) is increasingly being explored in trauma care as a tool to support clinical decision-making. OBJECTIVE: To ev...

Apr 17 2026 41996287
Association between diagnostic history and cancer incidence within 5 years: a real-world observational analysis.

Cancer is associated with many pre-existing health conditions (PHCs), but accurately quantifying these links remains challenging. Although some studie...

Apr 17 2026 41996637
Development and validation of a novel blood-based biomarker for gastric cancer triage in chronic dyspepsia.

Global implementation of gastric cancer (GC) screening in chronic dyspepsia populations faces challenges due to the high number-needed-to-scope (NNS) ...

Apr 17 2026 41998063
A pyroptosis-related gene signature for the diagnosis of acute pancreatitis.

Acute pancreatitis (AP) is a severe inflammatory disorder in which pyroptosis-a pro-inflammatory form of programmed cell death-may contribute to patho...

Apr 17 2026 41996313
Cross-sectional research: Application of an Artificial Intelligence-Based Pediatric Early Warning Score in the Pediatric Emergency Department.

BACKGROUND: There are a large number of pediatric emergency patients. Due to the fact that the children cannot describe their own conditions, there is...

Apr 16 2026 41995245
Artificial Intelligence in Haemophilia Care: A Narrative Review of Current Evidence and Future Opportunities.

Artificial intelligence (AI) is increasingly explored in healthcare for its capacity to analyse complex data, support clinical decision-making and ena...

Apr 16 2026 41988806
From pathogenesis to precision medicine in systemic lupus erythematosus: Emerging biomarkers and targeted interventions.

Systemic lupus erythematosus (SLE) is a chronic, systemic autoimmune disease characterized by immune dysregulation, autoantibody production, and chron...

Apr 15 2026 42095089
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