Latest AI and machine learning research in hematology for healthcare professionals.
Accurate, non-invasive liver fibrosis detection is essential for chronic liver disease management, particularly with rising metabolic dysfunction-associated liver disease (MASLD) and chronic hepatitis B (CHB). While the Fibrosis-4 (FIB-4) index is widely used, its performance for advanced fibrosis is limited. We develop Met-FIB using metabolomics and machine learning, integrating FIB-4 parameters ...
UNLABELLED: Neutropenic fever (NF) is often the first sign of infection in patients with hematologic malignancies, but its cause is frequently unknown, leading to broad-spectrum antibiotic use without confirmed infections. Although research links gut microbiome disruptions to treatment-related infections, it typically examines NF as the outcome, leaving a gap in understanding how the microbiome an...
BACKGROUND: Type 2 diabetes (T2D) currently has no cure. However, extensive evidence suggests that addressing key risk factors through lifestyle chang...
INTRODUCTION: Joint bleeds are the most significant complication in haemophilia, leading to functional impairment and reduced quality of life. Repeate...
Pulmonary embolism (PE) is a common and potentially fatal venous thromboembolic disease. Traditional management paradigms, often characterized by insu...
INTRODUCTION: Platelet count and related indices obtained from the complete blood count (CBC) play an important role in the diagnosis, monitoring, and...
PURPOSE: Inflammatory-nutritional biomarker scores derived from routine blood tests have established prognostic value in cancer, yet their association...
Kidney disease is a major global health concern that requires timely diagnosis and effective monitoring to prevent severe complications and improve pa...
BACKGROUND: Bronchiectasis is a chronic neutrophilic respiratory disease frequently complicated by Pseudomonas aeruginosa (P. aeruginosa) infection. N...
BackgroundRandomised trials have demonstrated that early anticoagulation after acute atrial fibrillation-associated ischaemic stroke is safe and non-i...
BACKGROUND: Clinical endpoint classification (CEC) is the gold standard for cardiovascular endpoint measurement in clinical trials, but adds time and ...
INTRODUCTION: Prostate-specific antigen (PSA) alone is insufficient for the diagnosis of prostate cancer (PCa), particularly within the gray zone rang...
PURPOSE: The general population is at risk of exposure to ionizing radiation due to nuclear warfare, terrorism, or radiological accidents. Such exposu...
Plasma proteomic biomarkers hold significant promise for enhancing clinical assessments and improving early detection of psychosis conversion; however...
BACKGROUND: Thrombosis in rotary blood pumps arises from complex flow conditions that remain difficult to translate into reliable and interpretable ri...
Septic shock (SS), the most severe stage of sepsis, has a high mortality rate. Mitochondria-mediated programmed cell death (MPCD) plays a key role in ...
Intracranial aneurysms are pathological dilations of cerebral arteries affecting 3-5% of the population. Their rupture can cause subarachnoid hemorrha...
BACKGROUND: Accurate and rapid diagnosis is essential for controlling pulmonary tuberculosis (PTB) by enabling timely intervention and reducing diseas...
BACKGROUND AND OBJECTIVES: Molecular markers such as isocitrate dehydrogenase (IDH) and alpha-thalassemia/mental retardation syndrome X-linked (ATRX) ...
High-density lipoprotein (HDL)-related inflammatory ratios (monocyte-to-HDL cholesterol ratio [MHR], lymphocyte-to-HDL cholesterol ratio, neutrophil-t...