Hematology

Hemophilia

Latest AI and machine learning research in hemophilia for healthcare professionals.

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Showing 253-273 of 4,984 articles
Organ preservation in rectal cancer: an endoscopist's perspective on current evidence and future directions.

Rectal cancer management has increasingly shifted toward organ-preserving strategies that aim to mai...

(1)
Jan 2026 41609210
Role of WNK4 and FKBP5 in asthma: Insights from bioinformatics analysis, machine learning, and preliminary validation.

BACKGROUND: The complex and heterogeneous molecular mechanisms of asthma are currently unclear, and ...

Jan 2026 41610713
Computational identification of potential MMP-2 inhibitors in cancer using machine learning, molecular docking, and dynamics simulations.

Matrix metalloproteinase-2 (MMP-2) is a zinc-dependent endopeptidase which plays a key role in the e...

Jan 2026 41604734
Artificial intelligence in idiopathic pulmonary fibrosis: advances, challenges and future directions.

Idiopathic pulmonary fibrosis (IPF) is a progressive disease of unknown aetiology, characterised by ...

Jan 2026 41381227
Transcriptomic profiling and machine learning uncover gene signatures of psoriasis endotypes and disease severity.

BACKGROUND: Despite increased understanding of psoriasis pathogenesis, molecular classification of c...

Jan 2026 41565778
Exploring structural diversity and dynamic stability of small-molecule PRMT5 inhibitors through machine learning-based QSAR and molecular modelling.

Protein arginine methyltransferase 5 (PRMT5) is a key epigenetic enzyme that catalyses symmetric arg...

Jan 2026 41533017
NEIL1 suppresses ROS accumulation to promote temozolomide resistance and malignant progression in glioma cells.

BACKGROUND: Glioma is the most common malignant primary brain tumor. Temozolomide (TMZ) is the stand...

Jan 2026 41534309
Utilizing Machine Learning for Predicting PrEP Use Status Among Sexual and Gender Minority Young Adults.

Pre-exposure prophylaxis (PrEP) is a highly effective biomedical prevention tool for HIV yet remains...

(1)
Jan 2026 41519977
A chalcone-rich extract from licorice root inhibits liver steatosis and fibrosis via regulating PPARα and TGFβ signaling.

BACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a major liver disord...

Dec 2025 41539093
Evaluating Retrieval-Augmented Generation-Large Language Models for Infective Endocarditis Prophylaxis: Clinical Accuracy and Efficiency.

INTRODUCTION AND AIMS: The use of large language models (LLMs) in healthcare is expanding. Retrieval...

(1)
Dec 2025 41453288
CoREST complex inhibition alters RNA splicing to promote neoantigen expression and enhance tumor immunity.

Epigenetic macromolecular enzyme complexes tightly regulate gene expression at the chromatin level a...

Dec 2025 41364533
Targeting the DYNLL2-PAK1 axis inhibits caspase-11-dependent pyroptosis to alleviate sepsis.

Sepsis, a life-threatening syndrome caused by dysregulated host responses to infection, lacks effect...

Dec 2025 41360226
Precision treatment with artificial intelligence assisted subtyping enhances therapeutic efficacy in HR+/HER2- breast cancer: The LINUXtrial.

We report the results of LINUX (NCT05594095), a multicenter, randomized, controlled phase II platfor...

Dec 2025 41349543
Development of a predictive model for eosinophilia in patients treated with ampicillin/sulbactam or piperacillin/tazobactam.

AIM: We aim to identify risk factors for antibiotic-induced eosinophilia in hospitalized patients re...

Nov 2025 41257433
Deep learning and molecular dynamics reveal promising EZH2 inhibitors for epigenetic cancer targeting.

Fine-tuned REINVENT generative model integrated with structure- and ligand-based computational appro...

Nov 2025 41237543
Artificial intelligence in nephrology: predicting CKD progression and personalizing treatment.

Chronic kidney disease (CKD) represents a major and expanding global health challenge, with prevalen...

Nov 2025 41205136
Multiomic insights into the MPO-mediated NET formation pathway in alcohol-induced epilepsy risk.

Epilepsy is a highly prevalent chronic central nervous system disorder that imposes substantial soci...

Nov 2025 41674657
Leveraging the ADAM10 prodomain for selective inhibition to enhance recovery after myocardial infarction.

BACKGROUND AND PURPOSE: Inflammation plays a crucial role in the development and progression of nume...

Oct 2025 41063509
Multiomics combined with machine learning defines unique molecular subtypes of cholangiocarcinoma and identifies TNK1 as a therapeutic target.

BACKGROUND AND AIMS: Cholangiocarcinoma (CCA) is one of the most lethal cancers, characterized by mo...

Sep 2025 41020779
Nivolumab plus ipilimumab for potentially resectable hepatocellular carcinoma: Long-term efficacy and biomarker exploration.

BACKGROUND & AIMS: Immune checkpoint inhibitor-based combination therapy has demonstrated high objec...

(1)
Sep 2025 40972843
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