Hematology

Hemophilia

Latest AI and machine learning research in hemophilia for healthcare professionals.

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Showing 358-378 of 4,984 articles
Bowel preparation before elective right colectomy: Multitreatment machine-learning analysis on 2,617 patients.

BACKGROUND: In the worldwide, real-life setting, some candidates for right colectomy still receive n...

Sep 2024 39322486
Deep-Learning-Driven Discovery of SN3-1, a Potent NLRP3 Inhibitor with Therapeutic Potential for Inflammatory Diseases.

The NLRP3 inflammasome plays a central role in the pathogenesis of various intractable human disease...

Sep 2024 39302813
Prediction of Inhibitory Activity against the MATE1 Transporter via Combined Fingerprint- and Physics-Based Machine Learning Models.

Renal secretion plays an important role in excretion of drug from the kidney. Two major transporters...

Sep 2024 39254593
Development of a novel prognostic signature derived from super-enhancer-associated gene by machine learning in head and neck squamous cell carcinoma.

Dysregulated super-enhancer (SE) results in aberrant transcription that drives cancer initiation and...

(1)
Sep 2024 39244857
Novel molecular inhibitor design for Plasmodium falciparum Lactate dehydrogenase enzyme using machine learning generated library of diverse compounds.

Generative machine learning models offer a novel strategy for chemogenomics and de novo drug design,...

(2)
Aug 2024 39162960
Chemical analogue based drug design for cancer treatment targeting PI3K: integrating machine learning and molecular modeling.

Cancer is a generic term for a group of disorders defined by uncontrolled cell growth and the potent...

(1)
Aug 2024 39154146
Hybridizing mechanistic modeling and deep learning for personalized survival prediction after immune checkpoint inhibitor immunotherapy.

We present a study where predictive mechanistic modeling is combined with deep learning methods to p...

Aug 2024 39143136
Development and validation of a machine learning-based, point-of-care risk calculator for post-ERCP pancreatitis and prophylaxis selection.

BACKGROUND AND AIMS: A robust model of post-ERCP pancreatitis (PEP) risk is not currently available....

(2)
Aug 2024 39147103
Redefining a new frontier in alkaptonuria therapy with AI-driven drug candidate design via innovation.

A rare metabolic condition called alkaptonuria (AKU) is caused by a decrease in homogentisate 1,2 di...

Jul 2024 38996180
Construction of IRAK4 inhibitor activity prediction model based on machine learning.

Interleukin-1 receptor-associated kinase 4 (IRAK4) is a crucial serine/threonine protein kinase that...

(1)
Jul 2024 38970641
Synthesis, Docking, and Machine Learning Studies of Some Novel Quinolinesulfonamides-Triazole Hybrids with Anticancer Activity.

In the presented work, a series of 22 hybrids of 8-quinolinesulfonamide and 1,4-disubstituted triazo...

Jul 2024 38999109
Discovery of a Novel and Potent LCK Inhibitor for Leukemia Treatment via Deep Learning and Molecular Docking.

The lymphocyte-specific protein tyrosine kinase (LCK) plays a crucial role in both T-cell developmen...

(2)
Jun 2024 38847742
Machine Learning-Enhanced Quantum Chemistry-Assisted Refinement of the Active Site Structure of Metalloproteins.

Understanding the fine structural details of inhibitor binding at the active site of metalloenzymes ...

May 2024 38805564
The potential use of artificial intelligence for venous thromboembolism prophylaxis and management: clinician and healthcare informatician perspectives.

Venous thromboembolism (VTE) is the leading cause of preventable death in hospitalized patients. Art...

May 2024 38796561
Improving HIV preexposure prophylaxis uptake with artificial intelligence and automation: a systematic review.

OBJECTIVES: To identify studies promoting the use of artificial intelligence (AI) or automation with...

(1)
May 2024 38788206
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