Hematology

Hemophilia

Latest AI and machine learning research in hemophilia for healthcare professionals.

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Showing 442-462 of 4,162 articles
Risks and Benefits of Pharmacological Prophylaxis for Venous Thromboembolism Prevention in Patients Undergoing Robotic Partial Nephrectomy.

PURPOSE: We investigate the safety and efficacy of pharmacological venous thromboembolism prophylaxi...

Nov 2015 26626222
Highly predictive support vector machine (SVM) models for anthrax toxin lethal factor (LF) inhibitors.

Anthrax is a highly lethal, acute infectious disease caused by the rod-shaped, Gram-positive bacteri...

Nov 2015 26615468
Neutrophil Elastase Inhibitor Following Liver Resection: A Matched Cohort Study.

BACKGROUND: Sivelestat is a neutrophil elastase inhibitor (NEI) with positive impact on the respirat...

Nov 2015 26834789
Non-weight-based enoxaparin dosing subtherapeutic in trauma patients.

BACKGROUND: We report our experience dosing and monitoring enoxaparin with anti-factor Xa activity (...

Oct 2015 26850200
Gingipains from Porphyromonas gingivalis promote the transformation and proliferation of vascular smooth muscle cell phenotypes.

The aim of the present study was to ascertain the effect of Porphyromonas gingivalis cysteine protea...

Oct 2015 26770435
Effect of MRP2 and MRP3 Polymorphisms on Anastrozole Glucuronidation and MRP2 and MRP3 Gene Expression in Normal Liver Samples.

Anastrozole is an aromatase inhibitor (AI) used as adjuvant therapy for breast cancer. Anastrozole i...

Sep 2015 26985457
CYP19A1 Genetic Polymorphisms rs4646 and Osteoporosis in Patients Treated with Aromatase Inhibitor-Based Adjuvant Therapy.

OBJECTIVE: Third-generation aromatase inhibitors (AI) are potent suppressors of aromatase activity. ...

Jul 2015 27026757
Correlation of plasma crizotinib trough concentration with adverse events in patients with anaplastic lymphoma kinase positive non-small-cell lung cancer.

BACKGROUND: Crizotinib, an ATP-competitive receptor tyrosine kinase inhibitor of both anaplastic lym...

Mar 2015 26819719
A Stability-Indicating HPLC Method for the Determination of Fingolimod in Pharmaceutical Dosage Forms.

Fingolimod is an immunosuppressive agent which is used for the prophylaxis of organ transplantation ...

Sep 2014 26839803
A Bioprinted Head and Neck Cancer Organoid-Based Platform for Evaluating Multimodal Therapies

Treatment of advanced head and neck squamous cell carcinoma (HNSCC) often involves radiotherapy comb...

Pathway-Centric Integration of CRISPR Fitness with Molecular Features Draws Cancer State Maps

Cancer cells display heterogeneous pathway activity that shapes therapeutic vulnerability, but mappi...

Learning activator-inhibitor dynamics at the cell cortex with neural likelihood ratio estimation

A key question in cell biology is how cell-scale organization emerges from a given set of molecular ...

Spatial remodeling of the urothelial carcinoma tumor microenvironment shapes response to neoadjuvant atezolizumab

The ABACUS study was a single arm, phase II trial evaluating neoadjuvant atezolizumab in operable ur...

CT-Based Deep Foundation Model for Predicting Immune Checkpoint Inhibitor-Induced Pneumonitis Risk in Lung Cancer

Background: Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy but can cause ser...

Multi-Objective Reinforcement Learning for Generating Covalent Inhibitor Candidates

Rational design of covalent inhibitors requires simultaneously optimizing multiple properties, such ...

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