Hematology

Hemophilia

Latest AI and machine learning research in hemophilia for healthcare professionals.

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Showing 106-126 of 4,984 articles
Multi-cohort integration and machine learning identify CPVL as a novel oncogenic driver in gastric cancer.

BACKGROUND: Gastric cancer (GC) remains a leading cause of cancer-related mortality worldwide, and t...

(1)
Jun 2026 42365218
Machine learning-driven prioritization and experimental validation of traditional Chinese medicine-derived STING-inhibitory candidates.

The stimulator of interferon genes (STING) is a key signalling adaptor in the cGAS-STING pathway of ...

(1)
Jun 2026 42360583
AI-enabled structural bioinformatics identifies repositioned kinase inhibitor against Poxviridae kinases.

BACKGROUND: Emerging zoonotic poxviruses such as lumpy skin disease virus (LSDV) and monkeypox pose ...

(1)
Jun 2026 42341425
Identification of small-molecule TNF-α inhibitor candidates using machine learning-guided screening and multiscale molecular modelling.

Lumbar disc herniation (LDH) is a major cause of chronic low back pain, in which tumor necrosis fact...

(1)
Jun 2026 42342749
Identifying Patients at Elevated Risk of Stroke After.

BACKGROUND: Transcarotid artery revascularization (TCAR) has assumed a significant role in the surgi...

(1)
Jun 2026 42323112
Accelerated development of 4-HPPD inhibitors using a hybrid deep learning approach with Bayesian-guided reinforcement learning.

Generative AI methods for enzyme inhibitor design are constrained by imbalanced training data and th...

(1)
Jun 2026 42348944
Identification and validation of exosome-related biomarkers in pediatric glioblastoma.

Pediatric glioblastoma (pGBM) is an aggressive central nervous system (CNS) tumor whose pathological...

(1)
Jun 2026 42319605
Discovery of TYR inhibitors from de novo molecular generation to dual-track lead optimization: "Competition" between AI and chemists.

This study introduces a unified framework combining artificial intelligence (AI)-directed de novo mo...

(1)
Jun 2026 42319927
Machine learning algorithms develop a tumor-educated platelets-related gene signature to predict colorectal cancer prognosis and therapy response.

Tumor-educated platelets (TEPs) have recently emerged as an important component of liquid biopsy, ye...

(1)
Jun 2026 42375537
Heterogeneity of Clazosentan Benefit after Aneurysmal Subarachnoid Hemorrhage Demonstrated in an Externally Validated Causal Policy Tree.

BACKGROUND: Clazosentan reduces angiographic vasospasm after aneurysmal subarachnoid hemorrhage (aSA...

(1)
Jun 2026 42310190
Single-cell multi-omics dissection of RevitalAge Markers uncovers age-dependent immunotherapy resistance and druggable targets in melanoma.

Aging-related molecular reprogramming profoundly influences melanoma progression and therapeutic sen...

(1)
Jun 2026 42304383
Integrating Machine Learning and Structure-Guided Discovery of a Novel Type II SYK Inhibitor for Treating Triple-Negative Breast Cancer.

Spleen tyrosine kinase (SYK) is a cytoplasmic nonreceptor kinase involved in immune signaling and ho...

(1)
Jun 2026 42304805
[Construction and validation of a prognostic prediction model for children-onset initial steroid-resistant nephrotic syndrome].

Objective: To analyze the risk factors for poor prognosis in children with steroid-resistant nephrot...

(1)
Jun 2026 42298853
Identification of compounds that repress DUX4 expression in facioscapulohumeral muscular dystrophy.

Facioscapulohumeral muscular dystrophy (FSHD) is caused by epigenetic dysregulation of the disease l...

(1)
Jun 2026 42304059
Fusion prediction model for post-ERCP pancreatitis under NSAIDs prophylaxis.

BACKGROUND: Endoscopic retrograde cholangiopancreatography (ERCP) is a common procedure for treating...

(1)
Jun 2026 42298037
Long-term outcomes with emicizumab prophylaxis for haemophilia A in China: A multicentre, large-cohort retrospective study.

Emicizumab is an established prophylactic therapy for haemophilia A (HA). However, real-world multic...

(1)
Jun 2026 42298304
RRBP1 promotes osimertinib resistance by activating fatty acid oxidation-dependent metabolic and immune reprogramming in EGFR-Mutant lung adenocarcinoma.

Osimertinib is a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor ...

(1)
Jun 2026 42285369
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