Hematology

Hemophilia

Latest AI and machine learning research in hemophilia for healthcare professionals.

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Advances in quantum dot-based fluorescent biosensors for enzyme detection: mechanistic insights and applications in disease.

It is imperative to develop precise detection tools for enzymes, as key biomarkers in disease pathog...

(3)
May 2026 42184024
Transcriptional states define dependencies and therapeutic vulnerabilities in head and neck cancer.

Molecular heterogeneity in head and neck squamous cell carcinoma (HNSCC) is well recognized, yet exi...

(1)
May 2026 42185641
Developments in the design and therapeutic applications of GSK3β inhibitors.

Glycogen synthase kinase-3β (GSK3β) has emerged as one of the most thoroughly validated therapeutic ...

May 2026 42169497
Guideline-Aligned Machine Learning for Predicting Ondansetron Administration at the End of Anaesthesia: Explainable Decision Support for PONV Prophylaxis.

Artificial Intelligence (AI) and Clinical Practice Guidelines (CPGs) both aim to support clinical de...

May 2026 42174910
Blocking MOXD1-derived ACOX1 peroxisome trafficking suppresses metabolic dysfunction-associated steatohepatitis.

BACKGROUND: Metabolic dysfunction-associated steatohepatitis (MASH) has become a major global health...

(1)
May 2026 42167911
Immune Checkpoint Inhibitor-Associated Cardiovascular Toxicity: Mechanisms, Clinical Manifestations, and Clinical Impact.

Immune checkpoint inhibitors (ICIs) represent a class of novel anticancer agents that enhance T cell...

May 2026 42162235
Xiao Zhen Fang mitigates cutaneous toxicity by inhibiting PANoptosis: Insights from untargeted metabolomics and transcriptomics.

BACKGROUND: Epidermal growth factor receptor (EGFR) inhibitors and other targeted therapies frequent...

(1)
May 2026 42167452
Synthetic Inducible Bacteria Normalize the Microenvironment of Refractory Tumors, Potentiating Checkpoint Inhibitor Responses.

Immunotherapy has transformed cancer treatment but remains ineffective in many solid tumors, largely...

May 2026 42145056
Integrative multi-omics analysis identifies a core ferroptosis signature and validates resveratrol as a novel inducer in pancreatic cancer.

Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis due to treatment resistance and an im...

(1)
May 2026 42142137
Immunological Drug-Drug Interactions in Immune Checkpoint Inhibitor Therapy: Mechanisms, Clinical Evidence, and Artificial Intelligence.

PURPOSE OF REVIEW: Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, producing du...

May 2026 42133231
Multimodal interpretable deep learning for transcriptome-informed precision oncology and drug mechanism analysis.

Precision oncology faces critical challenges in interpreting complex cellular signals and predicting...

May 2026 42129298
CT-based radiomic markers to predict late-onset seizures after traumatic brain injury.

Post-traumatic epilepsy (PTE) is a major long-term complication of traumatic brain injury (TBI), but...

(1)
May 2026 42120454
Insights into SIRT2 inhibition from machine learning-assisted multi-level screening of the NCI database.

The nicotinamide adenine dinucleotide (NAD+)-dependent deacetylase Sirtuin 2 (SIRT2) plays a regulat...

May 2026 42115733
Artificial intelligence-driven rational design and optimization of a potent terpenoid-derived PCSK9 inhibitor.

Hypercholesterolemia is a pivotal risk factor for cardiovascular diseases, and its effective managem...

May 2026 42105138
ELOVL1 promotes the progression of intrahepatic cholangiocarcinoma by enhancing endoplasmic reticulum stress and the PI3K/AKT/mTOR signaling pathway.

BACKGROUND: Intrahepatic cholangiocarcinoma (iCCA) is a highly aggressive liver malignancy character...

May 2026 42104482
Managing multidrug resistant Gram-negative bacteraemia in immunocompromised hosts.

PURPOSE OF REVIEW: Multidrug-resistant Gram-negative bloodstream infections (MDR-GNBSI) are increasi...

May 2026 42107119
Identification of non-hydroxamate histone deacetylase 8 inhibitors using deep learning-based screening of two-dimensional molecular images.

Histone deacetylase 8 (HDAC8) is a zinc-dependent enzyme that deacetylates proteins and is involved ...

May 2026 42107269
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