Hypertension

Deep Learning-Based Early Prediction of Syncope Onset During Tilt Table Testing via Temporal Convolutional Autoencoder Anomaly Detector.

INTRODUCTION: The head-up tilt table test (HUTT) is a lengthy and uncomfortable procedure for patients which often induces fainting. Post-transient loss of consciousness, nausea, vomiting, and pallor may occur. This study aims to develop and evaluate the efficacy of anomaly detection methods based on autoencoding for early prediction of syncope onset, enabling preemptive HUTT termination and there...

A Multimodal Learning Framework for Detecting Systemic Hypertension in Sleep Apnea Patients Using ECG and PPG Signals.

Systemic hypertension (HTN) is a major cardiovascular comorbidity in patients with obstructive sleep apnea (OSA), yet these conditions are often diagnosed and managed independently, limiting integrated cardiovascular risk assessment. There is a significant gap in scalable automated frameworks for the screening of hypertension using routinely collected polysomnography (PSG) signals. To address this...

Composite small vessel disease scores predict hemorrhagic transformation after thrombectomy: a machine learning study.

BACKGROUND: Hemorrhagic transformation (HT) is a major complication of acute ischemic stroke (AIS), especially after mechanical thrombectomy (MT) and ...

Feasibility study of non-invasive blood pressure measurement based on multidimensional characteristics of radial artery pressure pulse wave.

OBJECTIVE: This study focuses on a non-invasive blood pressure prediction method based on radial artery pulse wave feature analysis, aiming to achieve...

Heart failure detection in electrocardiograms using Artificial Intelligence and pragmatic labelling.

The diagnosis of heart failure (HF) is resource-intensive, leading to severe underdiagnosis. This study proposes the use of a deep learning model to d...

Machine learning approaches in identifying factors associated with hypertension and undiagnosed hypertension in adults in rural areas of Bangladesh.

BACKGROUND: Hypertension is a major cause of death and disability, and undiagnosed cases are particularly dangerous as they can cause severe damage wi...

Identification of diagnostic and therapeutic roles of programmed cell death-related proteins in dilated cardiomyopathy: a multi-omics and experimental validation study.

Dilated cardiomyopathy (DCM) is a clinically heterogeneous cardiac disorder characterized by ventricular dilation and systolic dysfunction, with limit...

Explainable TabNet for gestational diabetes prediction with physician-in-the-loop and multi-site clinical validation.

BACKGROUND: Gestational diabetes mellitus (GDM) affects 15-25% of pregnancies worldwide and poses serious risks of macrosomia, preeclampsia, neonatal ...

Smartphone-Based Pupillometry for Noninvasive Detection of Elevated Intracranial Pressure in Nepali Acute Brain Injury Patients: A Pilot Study.

BACKGROUND: Intracranial hypertension is a life-threatening complication of acute brain injuries such as traumatic brain injury (TBI), subarachnoid he...

Admission blood pressure percentiles and in-hospital mortality in pediatric heart failure: a multicenter retrospective cohort study.

BACKGROUND: Pediatric heart failure (PHF) carries a high mortality burden, yet the prognostic value of admission blood pressure (BP) remains poorly de...

Development and validation of an explainable machine learning model using routine laboratory biomarkers for identifying prevalent MASLD: Evidence from two observational studies.

Although many predictive models for metabolic dysfunction-associated steatotic liver disease (MASLD) have been developed, their performance remains su...

Cuffless hemodynamic monitoring with physics-informed machine learning models.

Wearable technologies have the potential to transform ambulatory and at-home hemodynamic monitoring by providing continuous assessments of cardiovascu...

Metabolic, demographic, and behavioral risk factors predict brain structural variability in the general population: an analysis of the human connectome project young adults.

BACKGROUND: Understanding whether commonly available metabolic, demographic, and behavioral factors can explain variability in brain structure may sup...

Blood Pressure Assessment Across the Lifespan: Improving Clinical Research and Clinical Practice: A National Heart, Lung, and Blood Institute Workshop Report.

Hypertension is a modifiable risk factor for cardiovascular disease (CVD) and its prevalence is high in the United States and worldwide. Adequate char...

Peripheral retinal haemorrhage density on ultra-widefield imaging as a novel biomarker for predicting diabetic retinopathy progression: a 2-year longitudinal study in Asians.

AIMS: To evaluate whether predominantly peripheral lesions (PPLs) and other imaging biomarkers on ultra-widefield (UWF) photography can predict the pr...

Associations of Red Blood Cell Distribution Width-Derived Indicators and Their Longitudinal Dynamic Trajectories With Mortality Risk in Critically Ill Patients With Pulmonary Hypertension.

Red blood cell distribution width (RDW)-derived indicators have increasingly been recognized as biomarkers reflecting systemic inflammation and hemato...

A TyG-UHR-based machine learning model for screening lean MAFLD: development and external validation.

BACKGROUND: Lean metabolic dysfunction-associated fatty liver disease (MAFLD) is increasingly recognized but often goes unnoticed during health checku...

Cardiovascular Risk Stratification in Youth-Onset Type 2 Diabetes Using Machine Learning.

BACKGROUND: The rising incidence of youth-onset type 2 diabetes mellitus (T2DM), along with the risk of early cardiovascular complications, is concern...

EJHF expert consensus statement on the diagnosis and management of hypertrophic cardiomyopathy.

Hypertrophic cardiomyopathy (HCM) is the most prevalent genetic cardiac disease and a leading cause of heart failure, arrhythmia, and sudden cardiac d...

Myocardial relaxation, left ventricular filling, and exercise capacity in older subjects with dyspnea.

With aging, left ventricular (LV) early diastolic lengthening declines. Delayed or dyssynchronous untwisting and relaxation may slow and reduce fillin...