Infectious Disease

Highly efficient and durable Th1-biased protective immunity from a novel mRNA vaccine against RSV via AI-assisted antigen screening.

Respiratory syncytial virus (RSV) is a leading cause of severe respiratory illness, imposing a signi...

Microvascular inflammation in the kidney transplant, beyond acute antibody-mediated rejection.

PURPOSE OF REVIEW: Microvascular inflammation (MVI) is a central feature of allograft rejection, tra...

Agri-vision Bangladesh: A multi-crop augmented image dataset for automated disease diagnosis in Bottle Gourd, Zucchini, Papaya, and Tomato.

This article introduces Agri-Vision Bangladesh, a comprehensive, augmented image dataset designed to...

Machine learning models for early mortality prediction in severe fever with thrombocytopenia syndrome.

Severe fever with thrombocytopenia syndrome (SFTS) is a high-fatality viral disease where early mort...

Identification of the biomarkers associated with lipid metabolism and endoplasmic reticulum stress in pediatric sepsis through bioinformatics analysis and quantitative reverse transcriptase PCR (qRT-PCR) assay.

BACKGROUND: Sepsis constitutes a critical clinical condition characterized by organ failure and syst...

From inhibition to regulation: serpins in health and disease.

This issue of the Biomedical Journal highlights regulatory mechanisms that shape aging, disease prog...

Rapid Detection of NDM-Producing Carbapenem-Resistant Escherichia coli Using MALDI-TOF MS Combined with Machine Learning Techniques.

BACKGROUND: Carbapenem-resistant Escherichia coli (CREC) producing New Delhi metallo-beta-lactamase ...

AI-Driven nanofiber platforms for essential oil delivery in dry period cows: a sustainable strategy against mastitis and antimicrobial resistance.

The routine utilisation of prophylactic antibiotics in dairy cows during the dry period has been dem...

Renovating Neural Networks With Viral-Mediated Gene Transfer From A Tissue Contacting Matrix Mimic.

Neurodegenerative diseases such as Huntington's Disease (HD) have a significant impact on healthcare...

Droplet Digital CRISPR for Nucleic Acid Detection.

Droplet digital (dd) clustered regularly interspaced short palindromic repeats (CRISPR) integrates t...

Motion as a Language: Transformer-Based Classification of Antimicrobial Peptide Conformational Dynamics.

Antimicrobial peptides (AMPs) represent a promising alternative to traditional antibiotics against w...

A tri-omics and machine learning framework identifies prognostic biomarkers and metabolic signatures in sepsis.

Sepsis is a complex systemic inflammatory syndrome that currently lacks stable and specific biomarke...

Machine learning for identifying risk factors of nosocomial infection in cancer patients with immune checkpoint inhibitor-related pneumonia.

Innovations in skin microphysiological systems for nonclinical testing and FDA modernization.

Recent innovations in skin microphysiological systems (MPSs) have gained momentum following regulato...

Spatial variation in socio-economic vulnerability to Influenza-like Infection for the US population.

This study aims to quantify environmental health impacts and assess risk by understanding the dispro...

Artificial intelligence predicts healthcare workers' antibiotic use intentions from psychological and behavioral measures across multiple theories.

Antimicrobial resistance (AMR) remains a global health priority, partly driven by non-guideline-conc...

Correlation between oral disease and neurodegenerative disorders: Role of biological proteins for the modulation of oral-brain axis and gut-brain axis.

Biological proteins play a crucial role at the intersection of oral health and neuroscience, offerin...

Evaluation of a machine learning system for genomic antimicrobial susceptibility determination on a clinically representative test set.

UNLABELLED: Next-generation sequencing is anticipated to transform infectious disease treatment by e...

Stage-wise environmental recovery patterns and cross-domain interactions of planktonic bacterial communities in Zhanjiang Bay following typhoon disturbance.

Typhoon events can abruptly alter local biogeochemical cycles, which may strongly influence microbia...

Applied Causality to Infer Protein Dynamics and Kinetics.

The use of generative machine learning models, trained on the experimentally resolved structures dep...

Bacterial fructan-metabolizing enzymes: modular architecture and biotechnological potential.

Bacterial fructan-metabolizing enzymes exhibit substantial structural and mechanistic diversity to s...