Infectious Disease

Latest AI and machine learning research in infectious disease for healthcare professionals.

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Lung-DT: An AI-Powered Digital Twin Framework for Thoracic Health Monitoring and Diagnosis.

The integration of artificial intelligence (AI) with Digital Twins (DTs) has emerged as a promising approach to revolutionize healthcare, particularly in terms of diagnosis and management of thoracic disorders. This study proposes a comprehensive framework, named Lung-DT, which leverages IoT sensors and AI algorithms to establish the digital representation of a patient's respiratory health. Using ...

Feb 1 2024 38339678

A hope for ineffective antibiotics to return to treatment: investigating the anti-biofilm potential of melittin alone and in combination with penicillin and oxacillin against multidrug resistant-MRSA and -VRSA.

BACKGROUND: The emergence and rapid spread of multi-drug resistant (MDR) bacterial strains, such as methicillin-resistant (MRSA) and vancomycin-resistant (VRSA), have posed a significant challenge to the medical community due to their ability to form biofilm and develop resistance to common antibiotics. Traditional antibiotics that were once effective in treating bacterial infections are now bec...

Feb 1 2024 38370578
Compound Activity Prediction with Dose-Dependent Transcriptomic Profiles and Deep Learning.

Predicting compound activity in assays is a long-standing challenge in drug discovery. Computational models based on compound-induced gene expression ...

Jan 31 2024 38293736
Viral load kinetics and the clinical consequences of cytomegalovirus in kidney transplantation.

BACKGROUND: Despite advances in clinical management, cytomegalovirus (CMV) infection remains a serious complication and an important cause of morbidit...

Jan 31 2024 38361528
Multi-omics analysis identifies potential microbial and metabolite diagnostic biomarkers of bacterial vaginosis.

BACKGROUND: Bacterial vaginosis (BV) is a common clinical manifestation of a perturbed vaginal ecology associated with adverse sexual and reproductive...

Jan 29 2024 38284174
Mapping Extracellular Space Features of Viral Encephalitis to Evaluate the Proficiency of Anti-Viral Drugs.

The extracellular space (ECS) is an important barrier against viral attack on brain cells, and dynamic changes in ECS microstructure characteristics a...

Jan 29 2024 38243660
COVID-19 lateral flow test image classification using deep CNN and StyleGAN2.

INTRODUCTION: Artificial intelligence (AI) in healthcare can enhance clinical workflows and diagnoses, particularly in large-scale operations like COV...

Jan 29 2024 38348096
Psychometric evaluation of the DePaul Symptom Questionnaire-Short Form (DSQ-SF) among adults with Long COVID, ME/CFS, and healthy controls: A machine learning approach.

Long COVID shares a number of clinical features with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), including post-exertional malaise, s...

Jan 28 2024 38282368
A bipolar intuitionistic fuzzy decision-making model for selection of effective diagnosis method of tuberculosis.

OBJECTIVES: Tuberculosis (TB) is a contagious illness caused by Mycobacterium tuberculosis. The initial symptoms of TB are similar to other respirator...

Jan 26 2024 38280637
Diagnostic performance of deep learning models versus radiologists in COVID-19 pneumonia: A systematic review and meta-analysis.

PURPOSE: Although several studies have compared the performance of deep learning (DL) models and radiologists for the diagnosis of COVID-19 pneumonia ...

Jan 26 2024 38301371
Toward the eradication of medical diagnostic errors.

The medical community does not broadcast the problem, but there are many studies that have reinforced a serious issue with diagnostic errors. A recent...

Jan 25 2024 38271508
inhibition of biofilm and virulence factor production in azole-resistant strains of isolated from diabetic foot by stabilized tin (IV) oxide nanoparticles.

The advent of nanotechnology has been instrumental in the development of new drugs with novel targets. Recently, metallic nanoparticles have emerged a...

Jan 25 2024 38332949
AutoMolDesigner for Antibiotic Discovery: An AI-Based Open-Source Software for Automated Design of Small-Molecule Antibiotics.

Discovery of small-molecule antibiotics with novel chemotypes serves as one of the essential strategies to address antibiotic resistance. Although a c...

Jan 24 2024 38265916
Prevalence and antimicrobial resistance of spp. isolated from animal feed in Japan.

The rising prevalence of antimicrobial resistance (AMR) of bacteria is a global health problem at the human, animal, and environmental interfaces, whi...

Jan 24 2024 38327814
iDVEIP: A computer-aided approach for the prediction of viral entry inhibitory peptides.

With the notable surge in therapeutic peptide development, various peptides have emerged as potential agents against virus-induced diseases. Viral ent...

Jan 23 2024 38263811
Antimicrobial resistance crisis: could artificial intelligence be the solution?

Antimicrobial resistance is a global public health threat, and the World Health Organization (WHO) has announced a priority list of the most threateni...

Jan 23 2024 38254241
Comparison between a deep-learning and a pixel-based approach for the automated quantification of HIV target cells in foreskin tissue.

The availability of target cells expressing the HIV receptors CD4 and CCR5 in genital tissue is a critical determinant of HIV susceptibility during se...

Jan 23 2024 38263439
Application of multi-gene genetic programming to the prognosis prediction of COVID-19 using routine hematological variables.

Identifying patients who may develop severe COVID-19 has been of interest to clinical physicians since it facilitates personalized treatment and optim...

Jan 23 2024 38263446
Machine Learning Bolsters Evidence That D1, Nef, and Tat Influence HIV Reservoir Dynamics.

BACKGROUND: The primary hurdle to curing HIV is due to the establishment of a reservoir early in infection. In an effort to find new treatment strateg...

Jan 23 2024 38292079
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