Infectious Disease

Latest AI and machine learning research in infectious disease for healthcare professionals.

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Association between persistent organic pollutants and malaria incidence in mainland China: a population-based surveillance and modeling analysis.

BACKGROUND: This study investigates malaria incidence trends in mainland China from 2005 to 2020, to elucidate its epidemiological characteristics and investigate potential associations with air pollution. Reasonable prediction is of great significance to control the epidemic of malaria. METHODS: First, time series analysis and machine learning methods were employed to predict malaria incidence. W...

Jul 8 2026 42415025

Large language models as versatile predictive engines for notifiable infectious diseases.

Accurate forecasting of infectious disease cases and deaths is crucial for public health decision-making. Traditional statistical and machine learning approaches may be challenged by complex temporal patterns and heterogeneous surveillance data. We evaluated large language models (LLMs) for infectious disease forecasting. We collected monthly reported cases and deaths data from China National Noti...

Jul 8 2026 42418452
Explainable machine learning for the early differentiation of pediatric bronchopneumonia using routine laboratory parameters.

OBJECTIVE: Early differentiation of pediatric acute respiratory infections in outpatient and emergency settings is often hindered by nonspecific clini...

Jul 8 2026 42418473
Machine learning-enabled label-free SERS for microbial sensing: Toward robust, generalizable, and deployable workflows.

Label-free surface-enhanced Raman spectroscopy (SERS) combined with machine learning (ML) provides a rapid, reagent-light approach to microbial detect...

Jul 7 2026 42419011
Bioactive Peptides for Oral Diseases: Biomaterial-Assisted Therapeutics and Translational Applications.

Dental caries, periodontitis, oral mucosal inflammation, peri-implant infections, and oral tissue defects remain major clinical burdens. Conventional ...

Jul 7 2026 42411007
Bioactive environments to combat antimicrobial resistance: artificial intelligence and model-driven microbial biocontrol for living materials.

Antimicrobial resistance (AMR) continues to outpace development of new therapeutics. Many interventions focus on treating infection after it occurs, b...

Jul 7 2026 42411838
Enterococcus hirae Y-HS Alleviates Ulcerative Colitis by Activating PXR/Nrf2-mediated Metabolic-immune Crosstalk.

Ulcerative colitis (UC) is a chronic inflammatory bowel disease with limited non-invasive biomarkers and variable responses to probiotics. This study ...

Jul 7 2026 42412323
scVAEAT: An Integrative Attention-Augmented Variational Autoencoder for Predicting Single-Cell Perturbation Responses.

Understanding how individual cells respond to genetic or environmental perturbations is crucial for deciphering disease mechanisms and advancing preci...

Jul 7 2026 42412677
AI Meets Attitudes: Cross-Sectional Quantitative Study of COVID-19 Vaccine Hesitancy in Alaska's Diverse Communities.

BACKGROUND: The global COVID-19 vaccine rollout faces challenges from persistent hesitancy, especially in rural and underserved regions. Alaska's uniq...

Jul 7 2026 42413028
Hidden pathways of antimicrobial resistance: A review of environmental metagenomics and exposure risks in low-resource settings.

Antimicrobial resistance (AMR) is increasingly recognised as a One Health challenge in which environmental reservoirs play an important role in the pe...

Jul 7 2026 42413431
TACTIC: A transfer learning framework to predict drug interactions in emerging pathogens.

Machine learning (ML) is necessary to efficiently identify potent drug combinations within a large candidate space to combat drug resistance. However,...

Jul 7 2026 42413502
A systematic trust management system for RPL based IoT networks using machine learning.

As IoT networks continue to evolve, concerns about their security risks are growing. Several security gaps still exist within IoT systems like Blackho...

Jul 7 2026 42414346
Pangenome-guided immunoinformatics design and in silico characterization of a multi-epitope vaccine candidate against Acinetobacter baumannii with nanoparticle assembly potential.

Acinetobacter baumannii is a critical multidrug-resistant pathogen causing severe healthcare infections with high mortality, yet no licensed vaccine e...

Jul 7 2026 42414399
Development and validation of a machine learning model to preoperatively predict very early recurrence in patients with hepatitis B virus-related hepatocellular carcinoma.

Very early recurrence (within one year) after curative hepatectomy significantly impairs long-term survival in patients with hepatitis B virus (HBV)-r...

Jul 7 2026 42414437
From Gram Stain to Decision Support: Performance of Multimodal Large Language Models in Blood Culture Microscopy.

Multimodal large language models (LLMs) offer significant potential for image-based diagnostics, yet their reliability in routine clinical microbiolog...

Jul 7 2026 42414723
A hybrid machine learning framework with two-step feature selection for identifying key biomarkers and drug targets in monkeypox.

Monkeypox (Mpox) is a viral disease that has garnered global attention due to its human-to-human transmissibility and cross-species transmission. Rece...

Jul 6 2026 42434339
Magnetically actuated microrobotic system for sequential treatment of biofilm.

Biofilm-associated infections present a critical therapeutic challenge due to antibiotic resistance and impaired tissue healing. Here, we present a mi...

Jul 6 2026 42406953
Robustness of a neural network approved for skin cancer diagnosis against variations in sequential images.

BACKGROUND: Convolutional neural networks (CNN) for skin cancer classification have shown results comparable to dermatologists but are vulnerable to m...

Jul 6 2026 42411020
Advances in Antiviral Drug Development Targeting Viral Proteases.

Viral proteases are critical targets in antiviral drug development due to their essential role in the viral lifecycle and high conservation across vir...

Jul 6 2026 42411042
Impact of the COVID-19 pandemic on ischemic stroke hospitalizations and in-hospital outcomes in the United States: A survey-weighted cohort with predictive modeling.

INTRODUCTION: Ischemic stroke remains a leading cause of death in the United States, with the COVID-19 pandemic exacerbating disparities. Prior studie...

Jul 6 2026 42413439
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