Infectious Disease

Latest AI and machine learning research in infectious disease for healthcare professionals.

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Preparation, characterization, and antibacterial activity of diclofenac-loaded chitosan nanoparticles.

Emerging antibiotic resistance necessitates the development of new therapeutic approaches. Many studies have reported the antimicrobial activity of diclofenac sodium (DIC) and chitosan nanoparticles (CNPs). Hence, this study aimed to prepare non-antibiotic DIC-loaded CNPs (DIC.CNPs) and characterize their antibacterial activity. DIC.CNPs were prepared from low and high molecular weight (LMW and H...

Aug 29 2018 30662310

Small Intestinal Bacterial Overgrowth in Patients With Cirrhosis.

Small intestinal bacterial overgrowth (SIBO) is defined by increased density and/or abnormal composition of microbiota in the small bowel. SIBO is often encountered in patients with cirrhosis as a result of impaired intestinal motility and delayed transit time, both of which are exacerbated by more severe liver disease. Additional risk factors for SIBO commonly encountered in cirrhotic patients in...

Aug 27 2018 31024208
Identification of a Novel Clinical Phenotype of Severe Malaria using a Network-Based Clustering Approach.

The parasite Plasmodium falciparum is the main cause of severe malaria (SM). Despite treatment with antimalarial drugs, more than 400,000 deaths are r...

Aug 27 2018 30150696
Evaluation of the Bactericidal and Fungicidal Activities of Poly([2-(methacryloyloxy)ethyl]trimethyl Ammonium Chloride)(Poly (METAC))-Based Materials.

Poly([2-(methacryloyloxy)ethyl]trimethyl ammonium chloride) (METAC) and the gels were prepared and evaluated for their bactericidal and fungicidal act...

Aug 26 2018 30960872
Ethambutol-induced optic neuropathy in renal disorder: a clinico-electrophysiological study.

OBJECTIVE: To report the spectrum of ethambutol induced optic neuropathy in a group of renal patients with tuberculosis and the role of visual evoked ...

Aug 25 2018 31109468
Management practices associated with strongylid parasite prevalence on horse farms in rural counties of Kentucky.

Anthelmintic resistance among cyathostomin parasites is a wide-spread problem. The parasite control guidelines written by the American Association of ...

Aug 23 2018 31014733
Spectral Identification of Disease in Weeds Using Multilayer Perceptron with Automatic Relevance Determination.

, a smut fungus, is studied as an agent for the biological control of (milk thistle) weed. Confirmation of the systemic infection is essential in ord...

Aug 23 2018 30142904
Computer-aided detection in chest radiography based on artificial intelligence: a survey.

As the most common examination tool in medical practice, chest radiography has important clinical value in the diagnosis of disease. Thus, the automat...

Aug 22 2018 30134902
BlaPred: Predicting and classifying β-lactamase using a 3-tier prediction system via Chou's general PseAAC.

Antibiotics of β-lactam class account for nearly half of the global antibiotic use. The β-lactamase enzyme is a major element of the bacterial arsenal...

Aug 20 2018 30138632
Prototype-Based Compound Discovery Using Deep Generative Models.

Designing a new drug is a lengthy and expensive process. As the space of potential molecules is very large ( Polishchuk , P. G. ; Madzhidov , T. I. ; ...

Aug 16 2018 30063142
Designing robot-assisted neurorehabilitation strategies for people with both HIV and stroke.

There is increasing evidence that HIV is an independent risk factor for stroke, resulting in an emerging population of people living with both HIV and...

Aug 14 2018 30107849
Antibacterial activity and its mechanisms of a recombinant Funme peptide against Cronobacter sakazakii in powdered infant formula.

Cronobacter sakazakii (Cs) is a typical foodborne bacterium that infect powdered infant formula (PIF) worldwide. In this study, a recombinant antimicr...

Aug 13 2018 30716944
Clinical prediction of HBV and HCV related hepatic fibrosis using machine learning.

Clinical prediction of advanced hepatic fibrosis (HF) and cirrhosis has long been challenging due to the gold standard, liver biopsy, being an invasiv...

Aug 10 2018 30100397
Establishment of a SVM classifier to predict recurrence of ovarian cancer.

Gene expression data using retrieved ovarian cancer (OC) samples were used to identify genes of interest and a support vector machine (SVM) classifier...

Aug 8 2018 30106117
Label-Free Biomolecule Detection in Physiological Solutions With Enhanced Sensitivity Using Graphene Nanogrids FET Biosensor.

Recently, graphene nanogrid sensor has been reported to be capable of sub-femtomolar sensing of Hepatitis B (Hep-B) surface antigen in buffer. However...

Aug 6 2018 30106685
Cell-Like Micromotors.

In the past decade, versatile micro- and nanosized machines have emerged as active agents for large-scale detoxification, sensing, microfabrication, a...

Aug 3 2018 30074758
Robotic selection for the rapid development of stable CHO cell lines for HIV vaccine production.

The production of envelope glycoproteins (Envs) for use as HIV vaccines is challenging. The yield of Envs expressed in stable Chinese Hamster Ovary (C...

Aug 2 2018 30071025
Deep Convolutional Neural Networks for Chest Diseases Detection.

Chest diseases are very serious health problems in the life of people. These diseases include chronic obstructive pulmonary disease, pneumonia, asthma...

Aug 1 2018 30154989
PIP-EL: A New Ensemble Learning Method for Improved Proinflammatory Peptide Predictions.

Proinflammatory cytokines have the capacity to increase inflammatory reaction and play a central role in first line of defence against invading pathog...

Jul 31 2018 30108593
A Rapid Bacteriophage DNA Extraction Method.

Bacteriophages (phages) are intensely investigated as non-antibiotic alternatives to circumvent antibiotic resistance development as well as last reso...

Jul 27 2018 31164569
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