Infectious Disease

Latest AI and machine learning research in infectious disease for healthcare professionals.

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A Comparative Study on Multifactor Dimensionality Reduction Methods for Detecting Gene-Gene Interactions with the Survival Phenotype.

Genome-wide association studies (GWAS) have extensively analyzed single SNP effects on a wide variety of common and complex diseases and found many genetic variants associated with diseases. However, there is still a large portion of the genetic variants left unexplained. This missing heritability problem might be due to the analytical strategy that limits analyses to only single SNPs. One of poss...

Aug 3 2015 26339630

Detection of abnormalities in ultrasound lung image using multi-level RVM classification.

The classification of abnormalities in ultrasound images is the monitoring tool of fluid to air passage in the lung. In this study, the adaptive median filtering technique is employed for the preprocessing step. The preprocessed image is then extracted the features by the convoluted local tetra pattern, histogram of oriented gradient, Haralick feature extraction and the complete local binary patte...

Jul 30 2015 26135771
Determination of vitamins, minerals, and microbial loads of fortified nonalcoholic beverage (kunun zaki) produced from millet.

The objective of this study was to evaluate the possibility of fortifying kunun zaki with tigernut milk extract due to nutritional deficiency of the f...

Jul 30 2015 26788315
Phytochemical, antimicrobial, and antioxidant activities of different citrus juice concentrates.

The search for new antimicrobial compounds is ongoing. Its importance cannot be overemphasized in an era of emerging resistant pathogenic organisms. T...

Jul 30 2015 26788316
Anti-inflammatory and antimicrobial activities of novel pyrazole analogues.

A new sequence of pyrazole derivatives (1-6) was synthesized from condensation technique under utilizing ultrasound irradiation. Synthesized compounds...

Jul 29 2015 27579011
MATEPRED-A-SVM-Based Prediction Method for Multidrug And Toxin Extrusion (MATE) Proteins.

The growth and spread of drug resistance in bacteria have been well established in both mankind and beasts and thus is a serious public health concern...

Jul 29 2015 26256800
Multivariate Quantitative Multifactor Dimensionality Reduction for Detecting Gene-Gene Interactions.

OBJECTIVES: To determine gene-gene interactions and missing heritability of complex diseases is a challenging topic in genome-wide association studies...

Jul 28 2015 26201702
Identifying Adverse Effects of HIV Drug Treatment and Associated Sentiments Using Twitter.

BACKGROUND: Social media platforms are increasingly seen as a source of data on a wide range of health issues. Twitter is of particular interest for p...

Jul 27 2015 27227141
Perspectives on next steps in classification of oro-facial pain - part 1: role of ontology.

The purpose of this study was to review existing principles of oro-facial pain classifications and to specify design recommendations for a new system ...

Jul 25 2015 26212927
Characterization of fecal vancomycin-resistant enterococci with acquired and intrinsic resistance mechanisms in wild animals, Spain.

The objectives were to evaluate the presence of vancomycin-resistant enterococci with acquired (VRE-a) and intrinsic (VRE-i) resistance mechanisms in ...

Jul 21 2015 26194421
Cheminformatics Based Machine Learning Models for AMA1-RON2 Abrogators for Inhibiting Plasmodium falciparum Erythrocyte Invasion.

Malaria remains a dreadful disease by putting every year about 3.4 billion people at risk and resulting into mortality of 627 thousand people worldwid...

Jul 17 2015 27490966
Apolipoprotein A-I: A Molecule of Diverse Function.

Apolipoprotein A-I (apo A-I) an indispensable component and a major structural protein of high-density lipoprotein (HDL), plays a vital role in revers...

Jul 16 2015 27382195
Intrawound Vancomycin Powder for Spine Tumor Surgery.

Study Design Retrospective evaluation of prospectively collected data. Objective To evaluate infection rates following intrawound vancomycin powder ap...

Jul 16 2015 27099810
Approach-Related Complications of Anterior Lumbar Interbody Fusion: Results of a Combined Spine and Vascular Surgical Team.

Study Design Retrospective analysis of prospectively collected cohort data. Objective Anterior lumbar interbody fusion (ALIF) is a commonly performed ...

Jul 16 2015 26933616
Automatic classification of diseases from free-text death certificates for real-time surveillance.

BACKGROUND: Death certificates provide an invaluable source for mortality statistics which can be used for surveillance and early warnings of increase...

Jul 15 2015 26174442
Detection and categorization of bacteria habitats using shallow linguistic analysis.

BACKGROUND: Information regarding bacteria biotopes is important for several research areas including health sciences, microbiology, and food processi...

Jul 13 2015 26201262
The contribution of co-reference resolution to supervised relation detection between bacteria and biotopes entities.

BACKGROUND: The acquisition of knowledge about relations between bacteria and their locations (habitats and geographical locations) in short texts abo...

Jul 13 2015 26201352
Genomics and Machine Learning for Taxonomy Consensus: The Mycobacterium tuberculosis Complex Paradigm.

Infra-species taxonomy is a prerequisite to compare features such as virulence in different pathogen lineages. Mycobacterium tuberculosis complex taxo...

Jul 8 2015 26154264
Multistage virtual screening and identification of novel HIV-1 protease inhibitors by integrating SVM, shape, pharmacophore and docking methods.

The HIV-1 protease has proven to be a crucial component of the HIV replication machinery and a reliable target for anti-HIV drug discovery. In this st...

Jul 6 2015 26185005
An efficiency analysis of high-order combinations of gene-gene interactions using multifactor-dimensionality reduction.

BACKGROUND: Multifactor dimensionality reduction (MDR) is widely used to analyze interactions of genes to determine the complex relationship between d...

Jul 1 2015 26126977
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