Infectious Disease

Latest AI and machine learning research in infectious disease for healthcare professionals.

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Dissecting Immune-Epithelial Interactions in Airway Infection at Single-Cell Resolution Using a Compartmentalised Microfluidic Device

Immune-epithelial interactions govern the initiation and progression of airway diseases, yet their heterogeneity is difficult to capture using existing in vitro models. Although conventional Transwell and lung-on-chip systems reproduce airway compartmentalisation and permit epithelial-immune interactions, they lack the spatial and analytical resolution needed to visualise dynamic immune behaviour ...

Giraffe: A Mapping Architecture from Hidden Text Representations to Visual Embeddings for Efficient Graphic Design

Multimodal large language models (MLLMs) have made significant progress in understanding and interpreting mul- timedia content. However, their ability to generate me- dia remains limited. Recent approaches have attempted to bridge this gap by translating the hidden representations of token sequences into the embedding space of visual models or directly into raw image data. However, these methods o...

Aug 25 2026 2608.23970v1
EMFE: A lightweight, explainable machine learning framework for malaria cell classification

Automated malaria diagnosis from stained blood-smear microscopy is dominated by deep convolutional neural networks that are accurate but computational...

Aug 25 2026 2608.24793v1
When Does Visual Generation Help Visual Understanding in Unified Multimodal Models?

Unified multimodal models (UMMs) can perform both understanding and generation, raising a central question: can visual generation improve understandin...

Aug 23 2026 2608.22174v1
Adapting Clinical Event Annotation to Dutch Primary Care: An Event Annotation Framework for Post-Acute Infection Syndromes

Extracting clinical information from Dutch free-text medical notes requires language-specific annotation resources, yet Dutch primary care lacks a reu...

Institutionalizing LLM-assisted decision support for malaria risk-focused ITN reprioritization in Nigeria: Digital competency, workplace resource profiles, experiences, and pathways to routine integration

Background In Nigeria, the country with the greatest global malaria burden, funding constraints increasingly require insecticide-treated net (ITN) rep...

On the robustness of scRNA-seq foundation models for plant perturbation response prediction under cross-experiment shift

Foundation models for single-cell transcriptomics promise to learn generalizable representations of cellular states. However, recent evidence suggests...

RegFM: an interpretable context-aware foundation model for human transcriptional regulation

Transcriptional regulation is governed by interactions between cis-regulatory elements (CREs) and trans-acting regulators in a context-specific manner...

Geographical targeting of active case finding for tuberculosis in Pakistan using artificial intelligence software: a qualitative study embedded within the SPOT TB trial

Background: Tuberculosis (TB) remains a critical public health challenge in Pakistan. The SPOT-TB trial evaluated MATCH-AI; an AI tool designed to geo...

Local retraining mitigates domain shift in sepsis prediction: Lessons from translating a neonatal model to mixed intensive care data

Background: Machine learning models leveraging electronic health records (EHRs) can support earlier detection of sepsis in intensive care units (ICUs)...

An AI-assisted platform for quantitative histopathological analysis in interstitial lung disease

Interstitial lung diseases (ILDs) are heterogeneous pulmonary disorders characterized by chronic inflammation and/or fibrosis. 30-40% of ILD patients ...

Physics-Informed Modeling of Biological Aging through DNA Methylation Entropy

Epigenetic clocks based on DNA methylation patterns are among the most accurate molecular correlates of chronological age, yet widely used clocks are ...

Microbial bioprospecting for benzoxazolinate-like molecules: unleashing the potential of genome mining

The benzoxazolinate moiety is a key functional group found in a few natural products (NPs), exhibiting diverse bioactivities, including antitumor, ant...

Ancient human mitochondrial genomes encode antimicrobial peptides

Mitochondria are bacteria-derived organelles that coordinate major innate immune pathways, but whether mitochondrial genomes themselves encode direct ...

Hepatitis C Virus Genotyping with a Transformer Neural Network

This study aims to explore the applicability of Transformer-based models for genetic sequence classification by evaluating their performance in predic...

Aug 19 2026 2608.19415v1
Data-Driven Geospatial Modeling and Forecasting of Malaria Burden to Support Control and Elimination in Africa

Malaria elimination is shaped by complex interactions among climatic, environmental, socioeconomic, demographic, health-system, and intervention-relat...

3D printing and deep learning enable holistic and dynamic analyses of tens of thousands of parasites infecting hundreds of genotypes

Host-parasite interactions are dynamic systems, where parasites usually outnumber hosts by one or more orders of magnitude. However, our understanding...

Proteoform Barcode: An Intuitive Visualization Framework for Top-Down Proteomics

Top-down proteomics (TDP) advances biomedical research by providing a birds-eye view of proteoforms in cells, tissues, and biofluids. Thousands of pro...

Machine Learning Prediction of Antimicrobial Response in Pleurotus ostreatus Extracts Cultivated on Cassava Peel: A Proof-of-Concept Study

Antimicrobial resistance has intensified the search for sustainable natural products with antimicrobial properties. Pleurotus ostreatus cultivated on ...

MaternaAI: Enhancing Equitable Maternal Healthcare in Kerala with Fairness-Aware and Explainable Learning Models

Maternal healthcare prediction systems often suffer from algorithmic biases due to socio-economic disparities and imbalanced datasets, limiting their ...

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