Latest AI and machine learning research in infectious disease for healthcare professionals.
Precision medicine aims to tailor healthcare strategies to individual differences in genetic, clinical, and environmental factors. However, identifying subgroup-specific causal relationships in complex biomedical data remains a major challenge, especially when standard causal inference methods average over population heterogeneity. We introduce DeepDiff-SHAP, a novel framework that combines regres...
The primate visual system excels in recognizing objects under challenging viewing scenario’s. A neural mechanism that is thought to play a key role in this ability is rapid temporal adaptation, or the adjustment of neurons’ activity based on recent history. To understand how temporal adaptation may support object recognition, previous work has incorporated a variety of temporal feedback mechanisms...
The non-polio enteroviruses enterovirus-D68 (EV-D68) and enterovirus-A71 (EV-A71) are highly prevalent and considered pathogens of increasing health c...
Gram-negative bacteria utilize a series of secretion systems (T1SS-T10SS) to deliver secreted effector proteins (T1SE-T10SE) into host cells, leading ...
Variation within the prokaryotic pangenome is not random, and natural selection that favours particular combinations of genes appears to dominate over...
Metabolic dysfunction–associated steatotic liver disease (MASLD) often coexists with chronic hepatitis B (CHB), yet early diagnosis remains challengin...
Self-assembling protein nanoparticles are being increasingly utilized in the design of next-generation vaccines due to their ability to induce antibod...
Cas9 nucleases are the effectors of the class 2 type II CRISPR system in bacteria and function to restrict invading DNA. They can also be used with si...
Broadly neutralizing antibodies (bNAbs) that target the envelope glycoprotein (Env) of human immunodeficiency virus-1 (HIV-1) have been utilized in cl...
The mechanisms by which two sister chromosomes separate and partition into daughter cells in bacteria remain poorly understood. A recent theoretical m...
Manual curation of biomedical literature is slow and error-prone and while large language models (LLMs) trained on general texts have shown to be usef...
Viral infections pose significant global health challenges, underscoring the urgent need for improved medications. Nevertheless, traditional medicinal...
Hepatitis B virus (HBV) infection causes approximately one million deaths annually and remains a major driver of hepatocellular carcinoma. Despite its...
Helicobacter pylori is a significant risk factor for gastric cancer, peptic ulcers, and MALT lymphoma. Rising antibiotic resistance rates complicate t...
RNA-based biosensors have emerged as essential tools in synthetic biology and diagnostics, enabling precise and programmable responses to diverse RNA ...
The ability of wildlife to live in anthropogenic structures is widely observed across many animal species. As proximity to humans is an important risk...
Large-language models (LLMs) can parse vast amounts of data and generate executable code, positioning them as promising tools for the development of b...
Pneumocystis jirovecii is a fungal pathogen causing Pneumocystis pneumonia in humans, mainly in immunocompromised individuals. Infections by P. jirove...
Persistent emergence of viral variants capable of evading host immunity constitutes a significant threat to public health. This antigenic evolution fr...
Antimicrobial resistance (AMR) is a pressing global health crisis, exacerbated by a stagnating antibiotic discovery pipeline and the emergence of mult...