Infectious Disease

Latest AI and machine learning research in infectious disease for healthcare professionals.

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Leveraging synthetic and genetic data to improve epidemic forecasting.

Forecasting infectious disease outbreaks is hard. Forecasting emerging infectious diseases with limited historical data is even harder. In this paper, we investigate ways to improve emerging infectious disease forecasting when little pathogen-specific training data are available. Specifically, we explore two sources of information that may be available near the start of an emerging disease outbrea...

Aug 27 2026 42658864

Artificial intelligence for healthcare in Nepal: A scoping review of clinical applications, implementation evidence, and health-system governance.

BACKGROUND: Nepal offers a distinctive LMIC setting for evaluating AI-health adoption due to its difficult geography, specialist shortage, high case burden needing screening and triage, and emerging digital-health policy reforms. OBJECTIVE: This scoping review aimed to synthesize existing literature on AI applications in medicine and healthcare in Nepal, including clinical use cases, education, im...

Aug 27 2026 42668712
CLIN-LLM: A safety-constrained hybrid framework for clinical diagnosis and treatment generation.

Accurate symptom-to-disease classification and clinically-grounded treatment recommendations remain challenging, particularly in heterogeneous patient...

Aug 27 2026 42658861
Deciphering Post-surgery Gut Microbial Dynamics in Colorectal Cancer through Multi-cohort Machine Learning.

Surgical resection, and its associated bowel preparation, remain the primary treatment for colorectal cancer (CRC), yet the associated effects on post...

Aug 26 2026 42645508
New WHO Blueprint and Digital Platform Look to Strengthen Surveillance of Fungal Disease and Antifungal Resistance.

Fungal disease and antifungal resistance are growing, historically underrecognized global threats that are difficult to detect and track. In this News...

Aug 26 2026 42647054
Can host genetics transform the sustainable control of tropical theileriosis? Insights from the Tick-Theileria interface.

Tropical theileriosis, caused by the tick-transmitted apicomplexan parasite Theileria annulata, remains a major constraint on cattle production across...

Aug 26 2026 42647970
PAC-Net: A physics-guided multimodal hybrid network for antibody-antigen interaction prediction.

The precise prediction of Antibody-Antigen Interaction (AAI) is a pivotal task for accelerating antibody drug discovery and virtual screening. To addr...

Aug 26 2026 42648458
Clinical phenotyping of bloodstream infections: a review of current evidence.

BACKGROUND: Bloodstream infections (BSIs) are a leading cause of morbidity and mortality, yet their clinical heterogeneity continues to challenge effe...

Aug 26 2026 42648482
MicroRNAs as novel therapeutics against multidrug-resistant ESKAPE pathogens: mechanisms, challenges, and future directions.

BACKGROUND: Multidrug-resistant (MDR) ESKAPE pathogens, including Enterococcus faecium, S. aureus, Klebsiella pneumoniae, Acinetobacter baumannii, P. ...

Aug 26 2026 42648582
Simulation-based inference of epidemiological and phylodynamic models via neural posterior estimation.

Mathematical models play a central role in understanding and forecasting infectious disease dynamics, but parameter inference is often difficult when ...

Aug 26 2026 42642063
Challenges and opportunities in type III secretion system effector prediction.

Type III secretion system effectors (T3SEs) are small bacterial proteins with big biological roles. They act as central molecular mediators of interac...

Aug 26 2026 42642068
AI-assisted MALDI-TOF MS for identifying carbapenem resistance in clinical Acinetobacter baumannii isolates.

Carbapenem-resistant Acinetobacter baumannii (CRAB) is one of the most critical public health threats worldwide due to its high infection rates, subst...

Aug 25 2026 42640968
Deep learning-based parasite detection for early and comprehensive diagnosis of animal trypanosomosis from thin blood smears.

The aim of this study was to assess the possibility of deep learning-based object detection models for the early and comprehensive detection of animal...

Aug 25 2026 42647969
[Development and validation of an explainable machine learning-based model for predicting mortality risk in polytrauma patients].

Polytrauma is commonly defined as multisystem trauma involving at least two body regions with an Abbreviated Injury Scale (AIS) score ≥ 3, characteriz...

Aug 25 2026 42656108
AMR-VSF: an adaptive memory correction framework for robust 3D CT aorta segmentation.

PURPOSE: Accurate 3D aortic segmentation in CT images is vital for cardiovascular disease diagnosis, surgical planning, and intraoperative navigation....

Aug 25 2026 42640529
Computational approaches in exploring the role of microRNAs in Human Cytomegalovirus infection.

Computational methods play a significant role in understanding the interaction between HCMV-encoded miRNAs with their targets. MicroRNAs have a regula...

Aug 25 2026 42641425
Investigating the effectiveness of multimodal data in forecasting SARS-COV-2 case surges.

OBJECTIVE: The COVID-19 pandemic response relied heavily on statistical and machine learning models to predict key outcomes such as case prevalence an...

Aug 25 2026 42641940
Microbiome-metabolome multi-omics biomarkers for infectious disease prognosis: Current evidence, AI-driven integration, and translational challenges.

Microbiome-metabolome interactions are emerging as promising predictors of infectious disease, beyond conventional pathogen detection. Growing evidenc...

Aug 25 2026 42642268
The Imaging Compass: Navigating Reperfusion in Acute Ischemic Stroke.

The management of acute ischemic stroke has shifted from rigid time-based protocols to imaging-driven, tissue-based reperfusion strategies. Non-contra...

Aug 25 2026 42642837
[Rational design and translational applications of hepatitis B virus-like particles].

Hepatitis B virus-like particles (HBV-VLPs), characterized by precise biomimetic topological architecture and favorable biocompatibility, have become ...

Aug 25 2026 42638047
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