Infectious Disease

Latest AI and machine learning research in infectious disease for healthcare professionals.

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Revolutionizing Personalized Cancer Vaccines with NEO: Novel Epitope Optimization Using an Aggregated Feed Forward and Recurrent Neural Network with LSTM Architecture

As cancer cases continue to rise, with a 2023 study from Zhejiang and Harvard predicting a 31 percent increase in cases and a 21 percent increase in deaths by 2030, the need to find more effective treatments for cancer is greater than ever before. Traditional approaches to treating cancer, such as chemotherapy, often kill healthy cells because of their lack of targetability. In contrast, persona...

Disentangling Interpretable Factors with Supervised Independent Subspace Principal Component Analysis

The success of machine learning models relies heavily on effectively representing high-dimensional data. However, ensuring data representations capture human-understandable concepts remains difficult, often requiring the incorporation of prior knowledge and decomposition of data into multiple subspaces. Traditional linear methods fall short in modeling more than one space, while more expressive ...

Assessing Concordance between RNA-Seq and NanoString Technologies in Ebola-Infected Nonhuman Primates Using Machine Learning

This study evaluates the concordance between RNA sequencing (RNA-Seq) and NanoString technologies for gene expression analysis in non-human primates...

Explainable convolutional neural network model provides an alternative genome-wide association perspective on mutations in SARS-CoV-2

Identifying mutations of SARS-CoV-2 strains associated with their phenotypic changes is critical for pandemic prediction and prevention. We compared...

Guide-LLM: An Embodied LLM Agent and Text-Based Topological Map for Robotic Guidance of People with Visual Impairments

Navigation presents a significant challenge for persons with visual impairments (PVI). While traditional aids such as white canes and guide dogs are...

ZIF-90 treats fungal keratitis by promoting macrophage apoptosis and inhibiting inflammatory response

Fungal keratitis is a severe vision-threatening corneal infection with a prognosis influenced by fungal virulence and the host's immune defense mech...

On-Site Precise Screening of SARS-CoV-2 Systems Using a Channel-Wise Attention-Based PLS-1D-CNN Model with Limited Infrared Signatures

During the early stages of respiratory virus outbreaks, such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the efficient utilize ...

Off-Policy Selection for Initiating Human-Centric Experimental Design

In human-centric tasks such as healthcare and education, the heterogeneity among patients and students necessitates personalized treatments and inst...

Omics-driven hybrid dynamic modeling of bioprocesses with uncertainty estimation

This work presents an omics-driven modeling pipeline that integrates machine-learning tools to facilitate the dynamic modeling of multiscale biologi...

Development of CODO: A Comprehensive Tool for COVID-19 Data Representation, Analysis, and Visualization

Artificial intelligence (AI) has become indispensable for managing and processing the vast amounts of data generated during the COVID-19 pandemic. O...

TELII: Temporal Event Level Inverted Indexing for Cohort Discovery on a Large Covid-19 EHR Dataset

Cohort discovery is a crucial step in clinical research on Electronic Health Record (EHR) data. Temporal queries, which are common in cohort discove...

On Novel Approach for Computing Distance based Indices of Anti-tuberculosis Drugs

This work aims to assess the molecular architectures of anti-tuberculosis drugs using both degree-based topological indices and novel distance based...

Estimating the Causal Effects of T Cell Receptors

A central question in human immunology is how a patient's repertoire of T cells impacts disease. Here, we introduce a method to infer the causal eff...

Contrastive learning of cell state dynamics in response to perturbations

We introduce DynaCLR, a self-supervised framework for modeling cell dynamics via contrastive learning of representations of time-lapse datasets. Liv...

Review on article of preoperative prediction in chronic hepatitis B virus patients using spectral computed tomography and machine learning.

This letter comments on the article that developed and tested a machine learning model that predicts lymphovascular invasion/perineural invasion statu...

Oct 14 2024 39493332
Deep-Ace: LSTM-based Prokaryotic Lysine Acetylation Site Predictor

Acetylation of lysine residues (K-Ace) is a post-translation modification occurring in both prokaryotes and eukaryotes. It plays a crucial role in d...

HyperBrain: Anomaly Detection for Temporal Hypergraph Brain Networks

Identifying unusual brain activity is a crucial task in neuroscience research, as it aids in the early detection of brain disorders. It is common to...

Uncovering the Viral Nature of Toxicity in Competitive Online Video Games

Toxicity is a widespread phenomenon in competitive online video games. In addition to its direct undesirable effects, there is a concern that toxici...

Unifying a Public Software Ecosystem: How Omaolo Responded to the COVID-19 Challenge

Public actors are often seen as slow, especially in renewing information systems, due to complex tendering and competition regulations, which delay ...

DEEP LEARNING-BASED FRAMEWORK TO DETERMINE THE DEGREE OF COVID-19 INFECTIONS FROM CHEST X-RAY.

The corona virus disease-19 (COVID-19) epidemic, the whole globe is suffering from a medical condition catastrophe that is unprecedented in scale. As ...

Oct 1 2024 39724901
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