Infectious Disease

Latest AI and machine learning research in infectious disease for healthcare professionals.

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Optimization of an improved chemically defined medium for high-efficiency expression of glucokinase in Escherichia coli.

BACKGROUND: Recombinant glucokinase (GLK), an important enzyme for blood glucose diagnostics, is commonly prepared in Escherichia coli (E.coli )for laboratory research and related biosynthetic applications. In small-scale laboratory cultivation, complex media are often used because of their convenience and strong growth-supporting capacity, but their ill-defined composition and batch-to-batch vari...

May 23 2026 42177533

The intelligent ear: AI and hearing aids information seeking and users' discussion on social media.

OBJECTIVES: Hearing aids are the primary technology used to compensate for hearing loss, yet conventional signal treatment algorithms often fall short of providing optimal performance in noisy situations. The rise of Artificial Intelligence (AI) is opening new avenues for more powerful hearing aids. However, information available for patients regarding AI and hearing aids is scarce. The purpose of...

May 22 2026 42190300
Development, validation, and implementation of the antibody-secreting cell maturity index: Universal prediction of human plasma cell maturity.

Defining the maturity of long-lived antibody-secreting cells (ASCs) is important for vaccine optimization and research into autoimmune diseases, but c...

May 22 2026 42221829
Empowering researchers and healthcare professionals in academic publishing: key insights and practical lessons from the British Society of Antimicrobial Chemotherapy (BSAC) workshop 2025.

The British Society of Antimicrobial Chemotherapy (BSAC) Academic Publishing Workshop, held at the Birmingham City Event Centre in the UK from 19 to 2...

May 22 2026 42179902
Tech-based evaluation of healthcare quality during the COVID-19 pandemic.

The coronavirus disease 2019 pandemic profoundly disrupted global health systems, exacerbating preexisting inequalities in access to and quality of ca...

May 22 2026 42175449
Phage ImmunoPrecipitation sequencing (PhIP-Seq) in autoimmunity research: From high-resolution epitope mapping to multi-omics integration.

Autoimmune diseases (AIDs) affect 5-10% of the global population, yet effective diagnosis and treatment remain challenging due to their complexity and...

May 22 2026 42176827
Advancing One Health: Innovations and Future Directions in Mycotoxin Detection, Management, and Prevention-Narrative Review.

Mycotoxins, toxic secondary metabolites generated by fungi such as Aspergillus, Fusarium, and Penicillium species pose substantial concerns to food sa...

May 22 2026 42176991
Detection of spider mite infestation via hyperspectral imaging and deep neural networks with spatial-spectral attention.

Early detection of spider mite emergence is highly challenging due to the lack of visible symptoms and subtle physiological changes. To address the ra...

May 22 2026 42169607
Metagenomic polymorphic toxin effector and immunity profiling predicts microbiome development and disease-related dysbiosis.

Bacteria use antagonistic interbacterial weapons, such as polymorphic toxin secretion systems (TSS), to compete for niches in the human gut microbiome...

May 22 2026 42171373
PathoFact 2.0: An Integrative Pipeline for the Prediction of Antimicrobial Resistance Genes, Virulence Factors, Toxins and Toxin-associated Proteins, and Biosynthetic Gene Clusters in Metagenomes.

BACKGROUND: Antimicrobial resistance genes (ARG) and virulence factors (VFs) are central contributors to the global health crisis surrounding drug-res...

May 22 2026 42172047
Transcriptome and experimental verification identified candidate biomarkers related to mitochondrial metabolism in sepsis-associated encephalopathy.

BACKGROUND: Mitochondrial metabolism (MM) abnormalities have been implicated in multiple diseases, but its contribution to sepsis-associated encephalo...

May 22 2026 42172235
Environmental Antibiotic Contamination and AMR: Integrating Pathways, Impacts, and AI-Driven Mitigation.

The widespread contamination of the environment with antibiotic residues is a significant factor contributing to the global crisis of antimicrobial re...

May 22 2026 42172586
Developing and validating a sequence-aware deep learning model for infection risk prediction in home care.

BACKGROUND: Infections are a leading cause of hospitalizations and emergency department (ED) visits in home care. Existing prediction tools often unde...

May 22 2026 42172726
An explainable machine learning model for early pediatric sepsis prediction using cytokine and routine laboratory data.

BACKGROUND: Early sepsis diagnosis in children remains challenging due to nonspecific presentations. This study aimed to develop an interpretable mach...

May 22 2026 42174201
Developing a Naïve Bayes risk classification machine learning algorithm to predict high viral load in a low-resource setting.

Access to routine viral load (VL) testing for people living with HIV (PLHIV) remains limited in many low-resource settings. There is a need for pragma...

May 22 2026 42172254
A qualitative study to inform the design and implementation of AI-driven diagnosis: Challenges, barriers, and clinical insights of physicians.

INTRODUCTION: Acute febrile illnesses are significant clinical challenge in tropical regions due to overlapping symptomatology among infections such a...

May 22 2026 42172279
Fine-scale structural information substantially improves mRNA therapeutic stability prediction.

The success of COVID-19 mRNA vaccines has made the in-solution stability optimization of mRNAs a key objective. However, we still lack a complete unde...

May 21 2026 42293245
Integrating Causal Inference and Agent-Based Modelling to Assess the Impact of Clinicians' Guideline Adherence in Older Adults Hospitalized with Pneumonia.

This study integrates agent-based modeling (ABM) and causal machine learning (ML) to assess the impact of clinicians' adherence to antibiotic guidelin...

May 21 2026 42174856
Knowledge-Based Interpretation of Multi-Modal Clinical Findings: Evaluating a Local Agentic Bridge Between Worlds.

Contemporary clinical practice still produces unstructured data like free-text reports or scans, hindering automated interpretation by knowledge-based...

May 21 2026 42174868
Automated Detection of Tuberculosis on Chest X-Rays Using Artificial Intelligence.

Detecting tuberculosis on X-rays remains complex and challenging for clinicians. In Burkina Faso, the scarcity of radiologists and their heavy workloa...

May 21 2026 42174873
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