Infectious Disease

Latest AI and machine learning research in infectious disease for healthcare professionals.

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Classification of Infectious and Noninfectious Diseases Using Artificial Neural Networks from 24-Hour Continuous Tympanic Temperature Data of Patients with Undifferentiated Fever.

Fever is one of the major clinical symptoms of undifferentiated fever cases. Early diagnosis of undifferentiated fever is a challenging task for the physician. The aim of this study was to classify infectious and noninfectious diseases from 24-hour continuous tympanic temperature recordings of patients with undifferentiated fever using a machine learning algorithm (artificial neural network). This...

Jan 1 2018 30055533

Association of Procalcitonin Value and Bacterial Coinfections in Pediatric Patients With Viral Lower Respiratory Tract Infections Admitted to the Pediatric Intensive Care Unit.

OBJECTIVE: Our primary objective was to determine the utility of procalcitonin (PCT) in detection of bacterial coinfection in children < 5 years admitted to the pediatric intensive care unit with viral lower respiratory tract infection (LRTI).

Jan 1 2018 30697132
Near Full-length Genomic Sequencing and Molecular Analysis of HIV-Infected Individuals in a Network-based Intervention (TRIP) in Athens, Greece: Evidence that Transmissions Occur More Frequently from those with High HIV-RNA.

BACKGROUND: TRIP (Transmission Reduction Intervention Project) was a network-based, contact tracing approach to locate and link to care, mostly people...

Jan 1 2018 30706819
The Spontaneous Control of HIV Replication is Characterized by Decreased Pathological Changes in the Gut-associated Lymphoid Tissue.

BACKGROUND: HIV infection induces alterations in the gut-associated lymphoid tissue (GALT) that constitutes the most important site for viral replicat...

Jan 1 2018 30706820
[Evaluation of the lateral flow Aspergillus assay for the diagnosis of invasive aspergillosis, experience in a university hospital].

BACKGROUND: The incidence of invasive aspergillosis is increasing. Its diagnosis is based on clinical and microbiological criteria which include the d...

Jan 1 2018 30725006
Prevalence of latent Mycobacterium tuberculosis infection in renal transplant recipients.

OBJECTIVE: To estimate the prevalence of latent Mycobacterium tuberculosis infection (LTBI) in renal transplant recipients and to assess sociodemograp...

Jan 1 2018 30726322
[Actinomyces with anti-candida activity isolated from leaf-cutting ants Atta cephalotes (Formicidae: Myrmicinae: Attini)].

OBJECTIVES.: To isolate, select and identify actinomyces associated to leaf-cutting ants Atta cephalotes (Linnaeus, 1758), that present a greater anti...

Jan 1 2018 30726428
Real World Patient-reported Outcomes in HIV-infected Adults Switching to EVIPLERA®, Because of a Previous Intolerance to cART. PRO-STR Study.

BACKGROUND: To investigate the impact of switching from stable Combined Antiretroviral Therapy (cART) to single-tablet regimen (RPV/FTC/TDF=EVIPLERA® ...

Jan 1 2018 30760189
Simultaneous HPTLC analysis and antileishmanic activity of various secondary metabolites in extract of the traditional medicinal herb (L.f.).

BACKGROUND: [(L.F) Bhandari] a medicinal plant is commonly known as 'Hari Champa' and its roots and fruits are used for treating malaria and scrofula...

Jan 1 2018 30783364
WAITING DAAS LIST MORTALITY IMPACT IN HCV CIRRHOTIC PATIENTS.

BACKGROUND: The infection for the hepatitis C virus (HCV) is a leading cause of liver-related morbidity and mortality through its evolution to liver c...

Jan 1 2018 30785516
Overview of the Biological Activities of a Methanol Extract from Wild Red Belt Conk, Fomitopsis pinicola (Agaricomycetes), Fruiting Bodies from Central Italy.

Fomitopsis pinicola (Sw.) P. Karst. (Fomitopsidaceae) is a medicinal mushroom with a variety of healthy properties. In this study we tested the radica...

Jan 1 2018 30806229
Factors Associated with HIV Viral Suppression Among Transgender Women in Lima, Peru.

PURPOSE: Globally, transgender women (TGW) experience a high burden of adverse health outcomes, including a high prevalence of HIV and sexually transm...

Jan 1 2018 30874476
Plasma and Cerebrospinal Fluid Beta-Endorphin Levels Show a Strong Association in Children with Cerebral Malaria.

BACKGROUND: Beta (β)-endorphins are endogenous neuropeptides found in the plasma and cerebrospinal fluid (CSF) of humans but there have been reports o...

Jan 1 2018 30937082
Formulation and solid state characterization of carboxylic acid-based co-crystals of tinidazole: An approach to enhance solubility.

BACKGROUND: Tinidazole (TNZ) is an anti-parasite drug used in the treatment of a variety of amebic and parasitic infections. It has low solubility in ...

Jan 1 2018 31033260
[Construction and high-density fermentation of alkaline pectate lyase high-yield yeast].

Pectate lyase is widely applied in ramie degumming and fabric bioscouring in the textile industry. Compared to conventional processes that involve hig...

Dec 25 2017 29271179
Procalcitonin in inflammatory bowel disease: Drawbacks and opportunities.

The measurement of procalcitonin has recently become a mainstay for the diagnosis and therapeutic management of severe bacterial infections, especiall...

Dec 21 2017 29307988
[Changes of platelet rheological behavior and the interventional effects of ulinastatin in rats with high-voltage electrical burns].

To explore the influence of high-voltage electrical burns on the number of platelet aggregation, β-thromboglobulin (β-TG) and platelet factor 4 (PF-4...

Dec 20 2017 29275615
Liver decompensation predicts ribavirin overexposure in hepatitis C virus patients treated with direct-acting antivirals.

AIM: To determine whether ribavirin (RBV) concentrations differ according to cirrhosis stage among cirrhotic patients treated with interferon-free reg...

Dec 8 2017 29290908
Machine learning: novel bioinformatics approaches for combating antimicrobial resistance.

PURPOSE OF REVIEW: Antimicrobial resistance (AMR) is a threat to global health and new approaches to combating AMR are needed. Use of machine learning...

Dec 1 2017 28914640
Prokaryotic Expression of Hepatitis C Virus-NS3 Protein and Preparation of a Monoclonal Antibody.

Hepatitis C virus (HCV) is a significant health threat that has been extensively investigated worldwide. Improving the sensitivity and specificity of ...

Dec 1 2017 29267148
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