Infectious Disease

Level of adrenomedullin in cases with adrenal defficiency and its relation to mortality in patients with sepsis.

INTRODUCTION: The aim of this study was to determine the prognostic value of adrenomedullin, after evaluation of adrenal function in sepsis patients. We also evaluated other prognostic factors such as APACHE II score, proBNP, and CRP and their prediction in mortality.

Fermentation, isolation, purification and characterization of an antitubercular antibiotic from Streptomyces luridus MTCC 4402.

Tuberculosis, caused by Mycobacterium tuberculosis, continues to be a serious public health problem around the world, and it urges the need for development of new antitubercular drugs. An antibiotic producing strain, Streptomyces luridus (MTCC 4402) was earlier isolated from soil by our group. In this work, the phylogenic status was established by 16S rRNA gene sequence analysis. The strain was fo...

Ventilator-Associated Pneumonia: Comparing Cadaveric Liver Transplant and Non-Transplant Surgical Patients.

Ventilator-associated pneumonia is a frequent complication in intensive care surgical patients, particularly those with high severity scores on admiss...

Research Advances in Bacteria-based Microrobot.

The concept of bacteria-based microrobot has been well recognized. It has shown great advantages and potentials for the early diagnosis and early trea...

A comparison of multimodal biomarkers for chronic hepatitis B assessment using recursive feature elimination.

An effective assessment of liver fibrosis in patients with chronic hepatitis B (CHB) is highly desired because it is important not only for clinical c...

Unsupervised selection of RV144 HIV vaccine-induced antibody features correlated to natural killer cell-mediated cytotoxic reactions.

HIV-1 vaccine injection has been shown less effective due to the diversity of antigens. Increasing the knowledge of the associations between immune sy...

[Cancer and genitourinary tuberculosis (literature review and clinical observations)].

Tuberculosis has been regarded as a counter-regulatory process to cancer. The development of tumors in the kidney that is affected by tuberculosis is ...

Intelligent hearing aids: the next revolution.

The first revolution in hearing aids came from nonlinear amplification, which allows better compensation for both soft and loud sounds. The second rev...

Difficulty understanding speech in noise by the hearing impaired: underlying causes and technological solutions.

A primary complaint of hearing-impaired individuals involves poor speech understanding when background noise is present. Hearing aids and cochlear imp...

Complementary sensors for rapid and sensitive detection of wound bacteria.

Dual sensors for timely wound bacterial infection detection through the measurement of pH and bacterial cell attachment were developed. A high sensiti...

MSLVP: prediction of multiple subcellular localization of viral proteins using a support vector machine.

Knowledge of the subcellular location (SCL) of viral proteins in the host cell is important for understanding their function in depth. Therefore, we h...

The power of data mining in diagnosis of childhood pneumonia.

Childhood pneumonia is the leading cause of death of children under the age of 5 years globally. Diagnostic information on the presence of infection, ...

Comparison of aglycon and glycosidic saponin extracts of tuber against spp.

BACKGROUND AND PURPOSE: Candidiasis, an important fungal infection, is considered the fourth most common nosocomial blood stream infection. Nowadays, ...

The importance of physicochemical characteristics and nonlinear classifiers in determining HIV-1 protease specificity.

This paper reviews recent research relating to the application of bioinformatics approaches to determining HIV-1 protease specificity, outlines outsta...

Evaluation of the Antimicrobial Functions of N-halamine Dental Unit Waterline Tubing for One Year.

OBJECTIVES: The objective of this study was to test the biofilm-controlling properties of N-halamine antimicrobial dental unit waterline (DUWL) tubing...

Automated analysis of food-borne pathogens using a novel microbial cell culture, sensing and classification system.

We hereby report the design and implementation of an Autonomous Microbial Cell Culture and Classification (AMC(3)) system for rapid detection of food ...

GI-SVM: A sensitive method for predicting genomic islands based on unannotated sequence of a single genome.

Genomic islands (GIs) are clusters of functionally related genes acquired by lateral genetic transfer (LGT), and they are present in many bacterial ge...

Computer-Aided Optimization of Combined Anti-Retroviral Therapy for HIV: New Drugs, New Drug Targets and Drug Resistance.

BACKGROUND: Resistance to antiretroviral drugs is a complex and evolving area with relevant implications in the treatment of human immunodeficiency vi...

Artificial Neural Network Analysis of Pharmacokinetic and Toxicity Properties of Lead Molecules for Dengue Fever, Tuberculosis and Malaria.

Poor pharmacokinetic and toxicity profiles are major reasons for the low rate of advancing lead drug candidates into efficacy studies. The In-silico p...

An Evaluation on Different Machine Learning Algorithms for Classification and Prediction of Antifungal Peptides.

BACKGROUND: Fungi are an emerging threat in medicine and agriculture and current therapeutics have proved to be insufficient and toxic. This has led t...