Infectious Disease

Latest AI and machine learning research in infectious disease for healthcare professionals.

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Evaluating Biomedical Feature Fusion on Machine Learning's Predictability and Interpretability of COVID-19 Severity Types: Model Development, Interpretation, and Validation.

BACKGROUND: Accurately differentiating severe from nonsevere COVID-19 clinical types is critical for the health care system to optimize workflow. Current techniques lack the ability to accurately classify COVID-19 clinical types in patients, especially as SARS-CoV-2 continues to mutate. OBJECTIVE: We explore the predictability and interpretability of multiple state-of-the-art machine learning (ML)...

Apr 30 2026 42060527

Enterocutaneous Fistula-Associated Sepsis and Mortality: Development and Validation of a Multimodal Artificial Intelligence Prediction Model.

BACKGROUND: Predicting enterocutaneous fistula (ECF)-associated sepsis and mortality poses significant challenges in digital health care due to the disease's complexity and heterogeneous clinical manifestations. Current approaches that rely on single-modal data or traditional scoring systems often fail to capture the intricate immune-inflammatory dynamics and multisystem involvement in patients wi...

Apr 30 2026 42060923
HyperHealth: a pilot study on AI-driven COVID-19 detection using hyperspectral fingertip images.

Despite the reduced impact of COVID-19 due to widespread vaccination and improved treatments, a critical need remains for accessible, scalable, and ra...

Apr 30 2026 42062352
Hypervariable loop profiling decodes sequence determinants of antibody stability.

Antibody folding and aggregation are major challenges in the development of relevant reagents and therapeutics. Antibodies face a biophysical trade-of...

Apr 30 2026 42062516
The Role of Artificial Intelligence Algorithms in Challenging Diagnostic Cases - Between Potential and Real Clinical Support.

INTRODUCTION: Extranodal natural killer/T-cell lymphoma, nasal type (ENKTL), is a rare EBV-associated malignancy characterized by destructive tumors i...

Apr 30 2026 42023639
Exploratory association between multimodal AI-derived digital biomarkers and in-hospital mortality in adult patients with pneumonia: A proof-of-concept study.

Pneumonia remains a leading cause of in-hospital mortality worldwide. Current prognostic tools such as the IDSA/ATS severity score have meaningful lim...

Apr 30 2026 42060654
Unlocking biodiversity data with robotic imaging and AI-driven transcription of natural history collections.

Digitizing metadata on natural history specimen labels remains a critical bottleneck for biodiversity research. We present a transformative workflow i...

Apr 29 2026 42054451
Repurposing Clinical Candidates for Nipah and Hendra Viruses.

Nipah virus (NiV) and Hendra virus (HeV) are bat-borne zoonotic paramyxoviruses that cause severe and often fatal respiratory and neurological disease...

Apr 29 2026 42052926
Quantitative three-dimensional imaging of Coxiella burnetii infection by focused ion beam-scanning electron microscopy.

Coxiella burnetii is a highly virulent intracellular pathogen and the causative agent of acute and chronic Q fever in humans. Central to its pathogeni...

Apr 29 2026 42053426
High-fidelity machine learning models for predicting antibacterial effects of cerium oxide nanoparticles across bacterial strains.

The primary objective of this study is to develop and validate robust data-driven models for accurately predicting bacterial growth inhibition induced...

Apr 29 2026 42053682
Thermal analysis of bioconvection flow of CNTs/water based hybrid nanofluid with gyrotactic microbes using artificial neural network.

This study uses the Levenberg-Marquardt strategy with feed forward neural networks (LMS-FNN) to inspect the Soret-Dufour effect on radiative hybrid na...

Apr 29 2026 42053732
Robust Radical-Mediated Electrical Enzyme Assay (REEA) Cartridge FET Sensor toward Practical Applications.

Field-effect transistor (FET)-based biosensors are promising tools for early infectious-disease detection; however, their real-world deployment is lim...

Apr 29 2026 42054104
Evolution and forecasting of antiretroviral therapy utilisation in British Columbia: a population-level analysis of provincial drug treatment programme data, 2014-2024.

OBJECTIVE: To characterise temporal trends in antiretroviral therapy (ART) utilisation and forecast short-term changes in regimen distribution within ...

Apr 29 2026 42055616
Explainable machine learning differentiates necrotizing fasciitis and osteomyelitis via routine blood biomarkers.

Necrotizing fasciitis (NF) and osteomyelitis (OM) are severe, limb-threatening infections with overlapping features, making early differentiation chal...

Apr 29 2026 42056542
Therapeutic targeting of Respiratory Syncytial Virus: Current pharmacological options and future directions in antiviral development.

Respiratory syncytial virus (RSV) remains a major cause of severe acute respiratory infections across the life course, particularly in infants, older ...

Apr 28 2026 42068597
Distinct bile mycobiome signature identifies fungal peptide panel predictive for gallbladder carcinoma.

Carcinoma of the gallbladder (CAGB) carries a poor prognosis. While alterations in the bile microbiome and lipidome have been linked to CAGB developme...

Apr 28 2026 42170678
Advances in mosquito-borne disease surveillance using machine learning.

Mosquito-borne diseases remain a major global health challenge, disproportionately impacting low- and middle-income countries. Despite traditional con...

Apr 28 2026 42164981
The Role of Molecular Testing in Head and Neck Squamous Cell Carcinoma of Unknown Primary.

Squamous cell carcinomas of unknown primary (SCCUP), accounting for approximately 5% of head and neck malignancies, present significant clinical chall...

Apr 28 2026 42047904
From generation to validation: Deep generative models for antimicrobial peptide discovery.

The global escalation of antibiotic resistance has renewed interest in antimicrobial peptides (AMPs) as promising alternatives to conventional antibio...

Apr 28 2026 42054758
AI-driven Predictive Models in Endourological Treatment of Urolithiasis: A Systematic Review of Nomogram Applications from EAU Endourology.

BACKGROUND: Artificial intelligence (AI) is increasingly applied in endourology to enhance surgical planning, risk stratification, and outcome predict...

Apr 28 2026 42055875
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