Infectious Disease

Gram staining decipherment using an artificial intelligence-powered smartphone-based application.

Gram staining provides rapid microbiological information that may assist in empirical antimicrobial ...

Machine Learning Models Using Hospital Admission Characteristics Do Not Optimally Predict Nosocomial Infection Development in a Global Cirrhosis Cohort.

BACKGROUND: Nosocomial infections (NI) in cirrhosis are associated with high mortality but could be ...

Multimodal Depression Detection Through Conversational Interactions with an Emotion-Aware Social Robot: Pilot Study.

BACKGROUND: Depression affects more than 300 million people worldwide and is a leading contributor t...

Antimycobacterial Peptides: From Natural Product Discovery to AI Guided Design.

Mycobacterial pathogens remain major global health threats, exacerbated by both rapid acquisition of...

DDA-BERT: end-to-end training for data-dependent acquisition mass spectrometry-based proteomics.

Peptide-spectrum match (PSM) rescoring is critical for accurate peptide identification in data-depen...

Augmented prediction of multi-species protein-RNA interactions using evolutionary conservation of RNA-binding proteins.

RNA-binding proteins (RBPs) play critical roles in the regulation of gene expression. Recent studies...

Bi-linguistic performance of large language models in multimodal analysis for differentiating jawbone-destroying malignancy from osteomyelitis.

Integrating microbial bioremediation, multi-omics, and emerging technologies for polycyclic aromatic hydrocarbon (PAHs) detoxification.

Environmental organic pollutants, identified as Polycyclic Aromatic Hydrocarbons (PAHs), are widespr...

Machine Learning-Guided Synthetic Microbial Communities Enable Functional and Sustainable Degradation of Persistent Environmental Pollutants.

Persistent environmental pollutants require diverse microbial metabolic capabilities for effective d...

Antibiotic resistance prediction with an attention-based bi-LSTM clinical decision support system.

BACKGROUND AND OBJECTIVE: Antimicrobial resistance is recognized by the World Health Organization as...

Plasma multi-omics profiling unravels molecular alterations and biomarker panels during recovery from severe coronavirus disease 2019: a pilot study.

BACKGROUND: The potential multidimensional molecular alterations during recovery of severe patients ...

Machine learning-enabled diagnosis of viral respiratory infections from exhaled volatile organic compound analysis.

Atomic clarity: how structural biology is shaping blood-stage malaria vaccines.

Developing an effective malaria vaccine is challenging because Plasmodium parasites use complex stra...

Toward Precise Risk Stratification after the Functional Cure of Chronic Hepatitis B.

Chronic hepatitis B remains a major global health challenge despite the advances in antiviral therap...

Identification and multi-layered experimental validation of feature genes related to butyrate metabolism and oxidative stress in sepsis.

The mechanisms underlying sepsis remain poorly understood and specific therapeutic options remain la...

Machine learning-empowered smartphone platforms for sustainable point-of-care bacterial detection.

Smartphone-based biosensing has rapidly evolved into a practical route for decentralized bacterial d...

The ecological framework of population health - Adding public trust as a forcing factor for U.S. life expectancy and COVID-19 mortality.

OBJECTIVES: What are the factors that set the stage for health status and outcomes in the United Sta...

Herbal extracts as antibiotic adjuvants against ESKAPE pathogens: mechanisms and therapeutic potential.

The escalating crisis of antimicrobial resistance, particularly driven by ESKAPE pathogens, poses a ...

Integrative multi-kingdom gut microbiome analysis uncovers clinical signatures of major depressive disorder.

BACKGROUND: Accumulating evidence indicates that gut microbiome is significantly altered in major de...

From modular engineering to practical applications: Advances in GPCR-based yeast biosensors.

G protein-coupled receptors (GPCRs) are pivotal biosensing elements for biosensors due to their high...

Dango: Predicting higher-order genetic interactions.

Higher-order genetic interactions have profound implications for understanding the molecular mechani...