Latest AI and machine learning research in intensivists for healthcare professionals.
Pyroptosis is a major contributor to the pathophysiology of acute liver failure (ALF), a condition with high mortality. Although N‑acetylcysteine (NAC) is used clinically for ALF, its mechanisms of regulating pyroptosis and multiple signaling pathways to achieve hepatoprotection remain incompletely understood. We integrated public transcriptomic data (GSE14668, GSE96851, GSE38941) and performed di...
Drug development productivity has not improved despite five decades of computational advancement, with the probability that a compound entering Phase I achieving regulatory approval remaining near 10%. Each automation wave increased throughput while leaving the interpretive bottleneck intact; scientists continued to formulate questions, evaluate outputs, and make advancement decisions regardless o...
BACKGROUND: The increasing documentation burden on physicians is a significant contributor to burnout and decreases in care quality. Artificial intell...
BACKGROUND: Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a common critical illness in the intensive care unit (ICU) and is ...
BACKGROUND: Postoperative delirium (POD) is a prevalent complication among older surgical patients; however, accurately predicting its occurrence usin...
Plastic pollution poses a major threat to the stability of natural ecosystems as well as human health. Microbial enzymes have long been considered a p...
Brain tumors remain among the most lethal cancers, largely due to their remarkable heterogeneity, plasticity, and resistance to therapy. The second Br...
BACKGROUND: Acute myocardial infarction (AMI) in critically ill patients is associated with high mortality. The glucose-to-platelet ratio (GPR), deriv...
Advances presented at the 2026 American Association for Cancer Research (AACR) Annual Meeting highlight a shift from standalone artificial intelligenc...
BACKGROUND: Artificial intelligence (AI) has been increasingly used in care delivery in intensive care units (ICUs) and anesthesia-critical care pract...
BACKGROUND: In intensive care unit (ICU) settings, structured team-based communication, such as multidisciplinary rounds, handoffs, and goals-of-care ...
BACKGROUND: Operating room (OR)-to-intensive care unit (ICU) handoffs are among the most complex and high-risk communication events in perioperative c...
BACKGROUND: The functional roles of the S100 protein family in colorectal cancer (CRC) are enigmatic, marked by widespread dysregulation but limited p...
The increasing advance of artificial intelligence (AI) in medicine will affect the future of Family Medicine in many ways. Some of the effects may be ...
Accurate and rapid characterization of lung mechanics remains a central challenge in respiratory disease management. Physics-informed poroelastic fini...
Current guidelines recommend albumin infusion as a first-line treatment for acute kidney injury (AKI) in patients with cirrhosis. However, recent larg...
Despite the obligation imposed by national and international accreditation standards to periodically verify reference intervals against local conditio...
Cyberbullying poses a substantial threat to adolescents' well-being, yet prevention efforts remain limited by insufficient understanding of its multil...
BACKGROUND: Artificial intelligence (AI)-enabled decision support systems are increasingly used in emergency departments and intensive care units to s...
OBJECTIVE: To explore the feasibility of developing an intraoperative real-time detection model for peritoneal nodules in laparoscopic colorectal canc...