Latest AI and machine learning research in kidney transplantation for healthcare professionals.
BACKGROUNDPrimary therapy for high-risk bladder cancer (BCa) is repeated instillations of the tuberculosis vaccine Bacillus Calmette-Guérin (BCG). Although BCG reduces the risk of recurrence by more than half, the mechanisms underlying its immune-activating effects remain unknown. Our objective was to investigate how the immune response differs between BCG responders and nonresponders and to compa...
Establishing a functional arteriovenous fistula (AVF) is crucial to ensure effective dialysis treatment. However, there are currently no definitive criteria for predicting AVF maturation using preoperative ultrasound. This study aims to assess the efficacy of AI-driven models in analyzing comprehensive ultrasonographic variables across multiple forearm locations to predict successful AVF maturatio...
In vivo chimeric antigen receptor (CAR) cell therapy is undergoing a transformative shift from conventional ex vivo manufacturing toward in situ cellu...
Cranio-maxillofacial bone defects resulting from trauma, tumors, infection, or congenital malformations not only severely impair patients' physiologic...
Pancreatic adenosquamous carcinoma (PASC) is a rare exocrine malignancy of the pancreas with an increasing incidence, histologically defined by the co...
BACKGROUND: Patients undergoing aortic-valve surgery are prone to perioperative low-cardiac-output syndrome or progression to cardiogenic shock, which...
Metastatic castration‑resistant prostate cancer (mCRPC) remains a lethal disease due to universal resistance to androgen‑receptor pathway inhibitors (...
Understanding transplantation outcomes requires an integrated view of immunological, genetic, and clinical determinants that collectively shape graft ...
Malachite green (MG), a synthetic dye, has turned into a major risk to human health, because of its toxicity of teratogenic, genotoxic, carcinogenic, ...
Diffuse large B-cell lymphoma (DLBCL) features an immunosuppressive tumor microenvironment (TME), yet the molecular drivers connecting metabolic repro...
Liver transplantation is the definitive treatment for end-stage liver disease; however, postoperative acute kidney injury (AKI) affects 30%-70% of rec...
Hepatocellular carcinoma (HCC) often exhibits limited responsiveness to immune checkpoint inhibitors (ICIs), largely due to an immunosuppressive tumor...
In an increasingly specialized medical landscape, Patient Blood Management (PBM) has emerged as a multidisciplinary and ethically grounded approach to...
This article highlights some important nephrology studies published in 2025 that are relevant for many nonnephrologist physicians. Two studies examine...
Personalized cancer vaccines have re-emerged as a promising strategy in precision immunotherapy, driven by advances in tumor sequencing, neoantigen id...
Prostate cancer (PCa) is among the most prevalent malignancies affecting men globally. The immunosuppressive characteristics of the tumor microenviron...
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a highly invasive and lethal malignancy, with its complex tumor microenvironment (TME) severely...
Soil organic carbon (SOC) is an important indicator of soil health and productivity in agricultural and natural ecosystems. Conventional measurement t...
This study suggests a new analysis pipeline of MEG data, uniquely designed for neural decoding of small-sized datasets. It combines classic methods th...
Tumor-associated macrophages (TAMs) are one of the main immunosuppressive components in the tumor microenvironment (TME). Growing evidence indicates t...