Transplantation

Kidney Transplantation

Latest AI and machine learning research in kidney transplantation for healthcare professionals.

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Comparing ACES AP0 and AP1 color primaries for smartphone colorimetry in detecting soil CO2 leakage with a beetroot (Beta vulgaris) biosensor.

Effective monitoring of CO2 leaks from carbon capture and storage (CCS) sites is vital to mitigate environmental risks, including soil acidification and ecosystem disruption. This study presents a novel, sustainable biosensor based on betanin from Beta vulgaris (beetroot) extract for pH-responsive colorimetric detection of soil CO2 leakage, coupled with smartphone imaging for quantitative analysis...

Jan 6 2026 41495487

Decoding Senescence-Driven Heterogeneity in Early-Onset Colorectal Cancer for Prognostic and Therapeutic Stratification.

Early-onset colorectal cancer (EOCRC), diagnosed in patients under 50, is particularly aggressive, yet lacks targeted therapeutic strategies. This study aimed to explore the role of cellular senescence in driving EOCRC's malignancy and developed a senescence scoring system (EO-Senscore) to guide precision oncology. Through a multi-omics analysis of 2961 patients, we discovered that cellular senesc...

Dec 28 2025 41456860
Post-Translational Modification Mediated By Acylation Modification Related Genes Induces Immunosuppression and Immunotherapy Resistance in Head and Neck Squamous Cell Carcinoma.

Acylation modification plays a crucial role in modulating head and neck squamous cell carcinoma (HNSCC) progression, and their specific prognostic imp...

Dec 26 2025 41439580
Integrative analysis of single-cell and bulk transcriptomes reveals metabolic heterogeneity and identifies PFKP as a therapeutic target in cervical cancer.

Cervical cancer (CC) is still a major gynecological tumor among women globally. The heterogeneity landscape and prognostic value of metabolic reprogra...

Dec 23 2025 41448552
Application of large language and artificial intelligence modeling in the prediction of peer-review outcomes.

OBJECTIVE: The rapid development of artificial intelligence (AI) presents an opportunity to streamline the peer-review process and provide key informa...

Dec 19 2025 41569893
Predicting postoperative length of stay: a feature selection approach to predictive modeling in lumbar fusion surgery.

BACKGROUND: Predictive modeling has the potential to improve preoperative planning and resource allocation in lumbar fusion surgery. This study aimed ...

Dec 18 2025 41410737
Cellular and molecular determinants of lymph node metastasis in papillary thyroid carcinoma: Integrated multi-omics profiling and machine learning models.

The mechanisms underlying lymph node metastasis (LNM) in papillary thyroid carcinoma (PTC) remain elusive. This study integrated single-cell RNA seque...

Dec 15 2025 41421038
Emerging nanoparticle-based therapies for pancreatic cancer: Current clinical landscape.

Pancreatic cancer, particularly ductal adenocarcinoma (PDAC) is one of the most aggressive and lethal subtypes due to late diagnosis, the absence of e...

Dec 12 2025 41391820
Decoding strategies for enhancing immunotherapy in head and neck squamous cell carcinoma.

Immune checkpoint inhibitors have partially improved treatment outcomes for patients with head and neck squamous cell carcinoma (HNSCC), but the respo...

Dec 10 2025 41380196
Smart transplant+: A HyCARE hybrid AI-cloud framework for intelligent donor-recipient matching, workflow automation, and post-transplant optimization.

Organ transplantation is a life-saving medical intervention to reverse end-stage organ failure. Despite its life-saving potential, organ transplantati...

Nov 27 2025 41317747
Turmeric extracellular vesicles-derived "all-in-one" nanoagent enables full-cycle synergistic immunomodulation of lung cancer.

Lung cancer's metastatic propensity and recurrence prevalence necessitate innovative immunotherapy strategies beyond conventional single-mode regulati...

Nov 27 2025 41399679
Current status and future directions for the use of artificial intelligence in pediatric critical care nephrology.

Artificial intelligence (AI) has the potential to significantly improve the practice of medicine. However, its application in pediatric critical care ...

Nov 25 2025 41291255
Deciphering the role of angiogenesis in glioblastoma: Integrative insights from transcriptomic profiling, single-cell sequencing and interpretable machine learning approaches.

Glioblastoma (GBM), a highly vascularized and aggressive primary brain tumor, presents unresolved questions regarding the functional significance of a...

Nov 24 2025 41380386
Explainable machine learning-based prediction of psoriatic arthritis flares using heterogenous real-world data for personalised patient care.

Psoriatic arthritis (PsA) is a chronic inflammatory disease characterised by unpredictable flare-ups that are difficult to forecast, particularly in p...

Nov 21 2025 41275993
Integrated multi-omics analyses identified the H3K18la-based spatiotemporal characteristics and risk-stratified treatment strategy in lung adenocarcinoma.

Lung adenocarcinoma (LUAD) is the most common histological type of lung cancer, characterized by high mortality, recurrence, and metastasis. Despite a...

Nov 20 2025 41274397
Learning curve for fenestrated-branched endovascular aortic repair using machine learning: A prospective national multicenter registry study.

OBJECTIVE: Fenestrated-branched endovascular aortic repair (F-BEVAR) is a complex procedure that requires significant experience and advanced technica...

Nov 19 2025 41265585
Mnemonic discrimination language evinces recollection rejection of similar lures.

Mnemonic discrimination of visual objects entails differentiating among repetitions of target objects, unstudied foil objects, and, critically, lure o...

Nov 13 2025 41231605
Artificial intelligence in nephrology: predicting CKD progression and personalizing treatment.

Chronic kidney disease (CKD) represents a major and expanding global health challenge, with prevalence rising due to aging populations, diabetes, hype...

Nov 8 2025 41205136
Responsible Use of Artificial Intelligence to Improve Kidney Care: A Statement from the American Society of Nephrology.

Artificial intelligence (AI) is rapidly transforming the delivery of kidney care through predictive analytics, machine learning, deep learning, and ge...

Nov 7 2025 41201255
4-Nonylphenol mediated tumor progression and immune modulation through CDK2: Computational and experimental validation.

As an endocrine-disrupting chemical, 4-nonylphenol (4-NP) has been found above safe limits in global water systems and associated with cancer progress...

Oct 27 2025 42336586
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