Kidney Transplantation

Characterization of sodium removal to ultrafiltration volume in a peritoneal dialysis outpatient cohort.

BACKGROUND: Failure to control volume is the second most common cause of peritoneal dialysis (PD) technique failure. Sodium is primarily removed by convection, but according to the three-pore model, water and sodium movements are not necessarily concordant. We wished to determine factors increasing sodium to water clearance in clinical practice.

Sulodexide modulates the dialysate effect on the peritoneal mesothelium.

Peritoneal membrane damage during chronic peritoneal dialysis is the main cause of that treatment failure. Preservation of the mesothelial cells (MC) is important for the survival of the peritoneum. Evaluation of dialysates effect on the function of MC and potential modification of that effect by sulodexide (heparin 80% and dermatan sulfate 20%). Dialysate effluents, after the overnight exchange w...

A Noninvasive Glucose Monitoring SoC Based on Single Wavelength Photoplethysmography.

Conventional glucose monitoring methods for the growing numbers of diabetic patients around the world are invasive, painful, costly and, time-consumin...

CFD based parameter tuning for motion control of robotic fish.

After millions of years of evolution, fishes have been endowed with agile swimming ability to accomplish various behaviourally relevant tasks. In comp...

Control of hyperparathyroidism with the intravenous calcimimetic etelcalcetide in dialysis patients adherent and non-adherent to oral calcimimetics.

BACKGROUND: In dialysis patients, non-adherence to oral cinacalcet adds complexity to the control of secondary hyperparathyroidism. The present study ...

First-in-human evaluation of a hand-held automated venipuncture device for rapid venous blood draws.

Obtaining venous access for blood sampling or intravenous (IV) fluid delivery is an essential first step in patient care. However, success rates rely ...

Machine Learning Approach for Fluconazole Resistance Detection Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry.

causes life-threatening systemic infections in immunosuppressed patients. These infections are commonly treated with fluconazole, an antifungal agent...

Technical Considerations and Confounders for Urine CXCL10 Chemokine Measurement.

BACKGROUND: The urine C-X-C motif chemokine 10 (CXCL10) is a promising screening biomarker for renal allograft rejection. The aim of the study was to ...

Effect of experimental infectious bursal disease virus on clinical signs and pathogenesis of avian influenza virus HN in turkey by real time PCR.

Infectious bursal disease virus (IBDV) in turkeys may result in immunosuppression, and inability of turkeys to resist nonpathogenic or less pathogenic...

Rapid Stability Indicating HPLC Method for the Analysis of Leflunomide and Its Related Impurities in Bulk Drug and Formulations.

OBJECTIVES: Leflunomide (LFNM) is a drug that belongs to isoxazole derivatives and has immunosuppressive and anti-inflammatory activities. A literatur...

The low-protein diet for chronic kidney disease: 8 years of clinical experience in a nephrology ward.

BACKGROUND: Guidelines indicate that a low-protein diet (LPD) delays dialysis in severe chronic kidney disease (CKD). We assessed the value of these g...

Predicting individual decision-making responses based on single-trial EEG.

Decision-making plays an essential role in the interpersonal interactions and cognitive processing of individuals. There has been increasing interest ...

Poly(ethylene glycol)-poly(ε-caprolactone)-based micelles for solubilization and tumor-targeted delivery of silibinin.

Silibinin is a naturally occurring compound with known positive impacts on prevention and treatment of many types of in general and cancer in partic...

Using machine learning techniques to develop risk prediction models to predict graft failure following kidney transplantation: protocol for a retrospective cohort study.

A mechanism to predict graft failure before the actual kidney transplantation occurs is crucial to clinical management of chronic kidney disease pati...

What microsurgeon, orthopaedic and plastic surgeon should know about bionic hand.

Hand loss is a catastrophic event that generates significant demands for orthopedics and prosthetics. In the course of history, prostheses evolved fro...

Comparing information extraction techniques for low-prevalence concepts: The case of insulin rejection by patients.

OBJECTIVE: To comparatively evaluate a range of Natural Language Processing (NLP) approaches for Information Extraction (IE) of low-prevalence concept...

Machine Learning Approach for Prediction of Hematic Parameters in Hemodialysis Patients.

This paper shows the application of machine learning techniques to predict hematic parameters using blood visible spectra during ex-vivo treatments. ...

Modeling of linear programming and extended TOPSIS in decision making problem under the framework of picture fuzzy sets.

Picture fuzzy sets (PFSs) are comparatively a new extension of fuzzy sets which describe the human opinions that has more answers like acceptance, rej...

Changes in clinical indicators related to the transition from dialysis to kidney transplantation-data from the ERA-EDTA Registry.

BACKGROUND: Kidney transplantation should improve abnormalities that are common during dialysis treatment, like anaemia and mineral and bone disorder....

Neural Mechanisms for Accepting and Rejecting Artificial Social Partners in the Uncanny Valley.

Artificial agents are becoming prevalent across human life domains. However, the neural mechanisms underlying human responses to these new, artificial...