Hematology

Leukemia

Latest AI and machine learning research in leukemia for healthcare professionals.

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Optimizing chemoradiotherapy for malignant gliomas: a validated mathematical approach

Malignant gliomas (MGs), particularly glioblastoma, are among the most aggressive brain tumors, with limited treatment options and a poor prognosis. Maximal safe resection and the so-called Stupp protocol are the standard first-line therapies. Despite combining radiotherapy and chemotherapy in an intensive manner, it provides limited survival benefits over radiation therapy alone, underscoring t...

TransST: Transfer Learning Embedded Spatial Factor Modeling of Spatial Transcriptomics Data

Background: Spatial transcriptomics have emerged as a powerful tool in biomedical research because of its ability to capture both the spatial contexts and abundance of the complete RNA transcript profile in organs of interest. However, limitations of the technology such as the relatively low resolution and comparatively insufficient sequencing depth make it difficult to reliably extract real bio...

Assessing the quality and readability of patient education materials on chemotherapy cardiotoxicity from artificial intelligence chatbots: An observational cross-sectional study.

Artificial intelligence (AI) and the introduction of Large Language Model (LLM) chatbots have become a common source of patient inquiry in healthcare....

Apr 11 2025 40228277
Leveraging Convolutional Neural Networks for Predicting Symptom Escalation in Chemotherapy Patients: A Temporal Resampling Approach.

This paper introduces a novel approach for predicting symptom escalation in chemotherapy patients by leveraging Convolutional Neural Networks (CNNs). ...

Apr 8 2025 40200443
Investigating AI Approaches for Survival Prediction in Chronic Lymphocytic Leukemia.

Chronic lymphocytic leukemia (CLL) exhibits a heterogeneous clinical course. Prognostic markers that impact patient outcomes have been identified, inc...

Apr 8 2025 40200453
Comparative Analysis of Unsupervised and Supervised Autoencoders for Nuclei Classification in Clear Cell Renal Cell Carcinoma Images

This study explores the application of supervised and unsupervised autoencoders (AEs) to automate nuclei classification in clear cell renal cell car...

Epidemiology characteristics and clinical outcomes of composite Hodgkin lymphoma and diffuse large B-cell lymphoma using machine learning.

Composite lymphoma (CL) is rare. We conducted an analysis of 53 329 cases of diffuse large B-cell lymphoma (DLBCL), 17,916 cases of Hodgkin lymphoma (...

Apr 4 2025 40219949
Leveraging Sparse Annotations for Leukemia Diagnosis on the Large Leukemia Dataset

Leukemia is 10th most frequently diagnosed cancer and one of the leading causes of cancer related deaths worldwide. Realistic analysis of Leukemia r...

Detecting Financial Fraud with Hybrid Deep Learning: A Mix-of-Experts Approach to Sequential and Anomalous Patterns

Financial fraud detection remains a critical challenge due to the dynamic and adversarial nature of fraudulent behavior. As fraudsters evolve their ...

Machine Learning Unveils Sphingolipid Metabolism's Role in Tumour Microenvironment and Immunotherapy in Lung Cancer.

TME is a core player in the development of a cancerous lesion, the immune evasive potential of the lesion, and its response to therapy. Sphingolipid m...

Apr 1 2025 40159631
EAP4EMSIG -- Enhancing Event-Driven Microscopy for Microfluidic Single-Cell Analysis

Microfluidic Live-Cell Imaging yields data on microbial cell factories. However, continuous acquisition is challenging as high-throughput experiment...

COIN: Confidence Score-Guided Distillation for Annotation-Free Cell Segmentation

Cell instance segmentation (CIS) is crucial for identifying individual cell morphologies in histopathological images, providing valuable insights fo...

Fully Unsupervised Annotation of C. Elegans

In this work we present a novel approach for unsupervised multi-graph matching, which applies to problems for which a Gaussian distribution of keypo...

Gaussian Random Fields as an Abstract Representation of Patient Metadata for Multimodal Medical Image Segmentation

The growing rate of chronic wound occurrence, especially in patients with diabetes, has become a concerning trend in recent years. Chronic wounds ar...

Multimodal AI predicts clinical outcomes of drug combinations from preclinical data

Predicting clinical outcomes from preclinical data is essential for identifying safe and effective drug combinations. Current models rely on structu...

Semantic Prior Distillation with Vision Foundation Model for Enhanced Rapid Bone Scintigraphy Image Restoration

Rapid bone scintigraphy is an essential tool for diagnosing skeletal diseases and tumor metastasis in pediatric patients, as it reduces scan time an...

BAMBI integrates biostatistical and artificial intelligence methods to improve RNA biomarker discovery.

RNA biomarkers enable early and precise disease diagnosis, monitoring, and prognosis, facilitating personalized medicine and targeted therapeutic stra...

Mar 4 2025 40121554
Adversarial Agents: Black-Box Evasion Attacks with Reinforcement Learning

Reinforcement learning (RL) offers powerful techniques for solving complex sequential decision-making tasks from experience. In this paper, we demon...

Towards Diagnostic Intelligent Systems in Leukemia Detection and Classification: A Systematic Review and Meta-analysis.

OBJECTIVE: Leukemia is a type of blood cancer that begins in the bone marrow and results in high numbers of abnormal white blood cells. Automated dete...

Mar 1 2025 40013326
Towards an AI co-scientist

Scientific discovery relies on scientists generating novel hypotheses that undergo rigorous experimental validation. To augment this process, we int...

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