Hematology

Leukemia

Latest AI and machine learning research in leukemia for healthcare professionals.

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Intelligent identification of osteoporosis on hip X-rays using vision transformer.

OBJECTIVE: This study aimed to develop and evaluate a deep learning model based on the Vision Transformer (ViT) architecture for the automatic classification of hip X-ray images into three categories: normal bone mass, osteopenia, and osteoporosis. The goal was to explore the model's potential for early screening and auxiliary diagnosis of osteoporosis. METHODS: A total of 3016 hip anteroposterior...

Jan 16 2026 41626401

Multiomics Profiling of T-cell Leukemia and Lymphoma Enables Targeted Therapeutic Discovery.

UNLABELLED: T-cell leukemias and lymphomas (TCL) form a heterogeneous group of rare and often aggressive malignancies. Because of the rarity and heterogeneity of TCL subtypes, clinical trials are challenging to conduct, making pharmacogenomic studies in cell line panels critical for the discovery of targeted therapeutics. The scarcity of data repositories with integrated multiomics and drug screen...

Jan 16 2026 41166698
Deep learning algorithm for semiquantification of spinal inflammation in axial spondyloarthritis.

OBJECTIVE: To develop a deep learning algorithm for semiquantification of spinal inflammation in patients with axial spondyloarthritis (SpA). METHODS:...

Jan 16 2026 41545311
Identification of COL8A2, MICAL2, and TNFSF10 as potential biomarkers associated with both exercise response and osteoarthritis: a multi-omics integration study.

UNLABELLED: To identify molecular biomarkers associated with both osteoarthritis (OA) pathology and exercise response through multi-omics integration....

Jan 14 2026 41550487
Comprehensive review on immunotherapy for hepatocellular carcinoma: Current status and future perspectives.

Hepatocellular carcinoma (HCC), the most common form of primary liver cancer, remains a major global health concern due to its high incidence and mort...

Jan 14 2026 41532498
On-chip characterization of cell mechanics assisted by external physical fields and artificial intelligence.

Traditional microfluidic chips for single-cell mechanical characterization face challenges such as cell aggregation and low throughput, limiting their...

Jan 14 2026 41532721
Nomograms Based on X-Ray Radiomics for Predicting Pain Progression in Knee Osteoarthritis Using Data From the Foundation for the National Institutes of Health: Development and Validation Study.

BACKGROUND: Knee osteoarthritis (KOA) is one of the most prevalent chronic musculoskeletal disorders among the older adult population. Screening popul...

Jan 14 2026 41534083
NEIL1 suppresses ROS accumulation to promote temozolomide resistance and malignant progression in glioma cells.

BACKGROUND: Glioma is the most common malignant primary brain tumor. Temozolomide (TMZ) is the standard first-line chemotherapy, but its efficacy is s...

Jan 13 2026 41534309
A nomogram model for challenging cases: differentiating fat-poor angiomyolipoma from clear cell renal cell carcinoma in uncertain or misdiagnosed tumors.

PURPOSE: To develop and validate a nomogram model that can accurately differentiate fat-poor angiomyolipoma (fp-AML) from clear cell renal cell carcin...

Jan 12 2026 41524985
Lightweight interpretable AI model using multiple blood parameters for emergency diagnosis of acute appendicitis.

BACKGROUND: Acute appendicitis poses diagnostic challenges due to symptom overlap with other abdominal conditions, often leading to misdiagnosis or mi...

Jan 12 2026 41570492
Machine learning assisted raman spectroscopy for the classification of ovarian cancer cells.

Ovarian cancer is one of the most lethal gynecological malignancies, asymptomatic early progression, ineffective screening, and high histological hete...

Jan 10 2026 41544326
Machine Learning-Based Prediction Model for Delayed Chemotherapy-Induced Nausea and Vomiting in Pediatric Cancer: A Prospective Cohort Study.

BACKGROUND: Delayed chemotherapy-induced nausea and vomiting (CINV) in pediatric oncology patients is currently under-recognized. This study aims to d...

Jan 10 2026 41518115
CellViT++: Energy-efficient and adaptive cell segmentation and classification using foundation models.

BACKGROUND AND OBJECTIVE: Deep learning-based cell segmentation and classification methods in digital pathology are critical for diagnostics but are h...

Jan 9 2026 41576779
Interpretable machine learning-based prediction of liver metastasis risk in elderly patients with small cell lung Cancer: A study based on the SEER database and external validation in a Chinese cohort.

PURPOSE: Small cell lung cancer (SCLC) is a highly aggressive malignancy with a high incidence of liver metastases, particularly among elderly patient...

Jan 8 2026 41518822
Patient Perceptions of Artificial Intelligence-Generated Kidney Transplant Information: Comparing ChatGPT With the National Kidney Foundation.

RATIONALE & OBJECTIVE: Generative artificial intelligence (AI) may help patients better understand the complexities of kidney transplantation. However...

Jan 8 2026 41767690
Chemo-prAIdict Breast: A deep learning solution for predicting residual disease on biopsies of breast cancer patients treated with neoadjuvant chemotherapy.

BACKGROUND: Predicting chemosensitivity before treatment could help tailor neoadjuvant chemotherapy (NAC) in early breast cancer (eBC). Pathological c...

Jan 7 2026 41518683
Association between the platelet to white blood cell ratio and short term mortality in critically ill patients with atherosclerotic cardiovascular disease: A retrospective study and machine learning with external validation.

BACKGROUND: The platelet to white blood cell ratio (PWR) has shown prognostic value in many diseases. Yet its predictive utility for patients with ath...

Jan 6 2026 41506173
Noninvasive real-time dynamic monitoring of white blood cells based on microscopic imaging and deep learning.

BACKGROUND AND OBJECTIVE: White blood cells (WBCs) are key biomarkers of immune status, but current monitoring still relies on intermittent blood samp...

Jan 5 2026 41505998
Reliable leukemia detection via transfer-enhanced Bayesian CNNs.

Accurate and early detection of Acute Lymphoblastic Leukemia (ALL) is critical for timely intervention and improved patient outcomes. However, the dev...

Jan 3 2026 41485393
Convolutional neural network-based image classification to understand breakup of oat cell structures due to high-pressure homogenization.

High-pressure homogenizers are used to disrupt oat cell aggregates in beverage processing applications. The mechanism of disruption remains poorly und...

Jan 2 2026 41703808
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