Oncology/Hematology

Lung Cancer

Latest AI and machine learning research in lung cancer for healthcare professionals.

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Showing 2301-2320 of 10,186 articles

Nanoscale Podocyte Morphometrics Predict Disease Progression in IgA Nephropathy

Introduction: Podocyte injury is central to the pathogenesis of most glomerulonephritides (GN) and causes segmental glomerulosclerotic lesions that predict progression in IgA Nephropathy (IgAN). Recent advances in high-resolution microscopy and AI-assisted image analysis have enabled detailed quantification of podocyte foot process (FP) morphology. However, whether nanoscale podocyte morphometrics...

Evaluating the Large Language Model-Based Quality Assurance Tool for Auto-Contouring

Purpose: Manual verification of AI-based auto-contouring is labor-intensive and prone to fatigue-related errors. This study developed the large language model (LLM)-based automated Quality Assurance (QA) for auto-contouring (LAQUA) system using a multimodal LLM, Gemini 2.5 Pro, and evaluated its feasibility as a clinical primary screening tool to streamline the QA workflow. Methods: Twenty male pe...

Knowledge-Guided Adversarial Training for Infrared Object Detection via Thermal Radiation Modeling

In complex environments, infrared object detection exhibits broad applicability and stability across diverse scenarios. However, infrared object detec...

Mar 26 2026 2603.25170v1
Automated Extraction of Cancer Registry Data from Pathology Reports: Comparing LLM-Based and Ontology-Driven NLP Platforms

Cancer data standardization requires converting unstructured pathology reports into structured registry variables, a mostly manual and resource-intens...

Agentic Automation of BT-RADS Scoring: End-to-End Multi-Agent System for Standardized Brain Tumor Follow-up Assessment

The Brain Tumor Reporting and Data System (BT-RADS) standardizes post-treatment MRI response assessment in patients with diffuse gliomas but requires ...

Mar 23 2026 2603.21494v1
Biophysics-Enhanced Neural Representations for Patient-Specific Respiratory Motion Modeling

A precise spatial delivery of the radiation dose is crucial for the treatment success in radiotherapy. In the lung and upper abdominal region, respira...

Mar 23 2026 2603.22123v1
Coupled Solvent and Protein Dynamics Confer Differences in Exon-19 Deletion Mutants of the Epidermal Growth Factor Receptor Kinase

Deletions in Exon-19 of the epidermal growth factor receptor (EGFR) play a pivotal role in the pathogenesis of non-small cell lung cancer (NSCLC), inf...

Learning from Limited and Incomplete Data: A Multimodal Framework for Predicting Pathological Response in NSCLC

Major pathological response (pR) following neoadjuvant therapy is a clinically meaningful endpoint in non-small cell lung cancer, strongly associated ...

Mar 16 2026 2603.15100v1
Fair Lung Disease Diagnosis from Chest CT via Gender-Adversarial Attention Multiple Instance Learning

We present a fairness-aware framework for multi-class lung disease diagnosis from chest CT volumes, developed for the Fair Disease Diagnosis Challenge...

Mar 13 2026 2603.12988v1
Multimodal classification of Radiation-Induced Contrast Enhancements and tumor recurrence using deep learning

The differentiation between tumor recurrence and radiation-induced contrast enhancements in post-treatment glioblastoma patients remains a major clini...

Mar 12 2026 2603.11827v1
Experimental multi-center validation of a radiomics-based photonic quantum precision medicine architecture for lesion-level prediction of anti-PD-1 response in non-small cell lung cancer

Background: Previous research has shown that radiomics-based machine learning models are promising precision medicine tools for lesion-level predictio...

A Lightweight Multi-Cancer Tumor Localization Framework for Deployable Digital Pathology

Accurate localization of tumor regions from hematoxylin and eosin-stained whole-slide images is fundamental for translational research including spati...

Mar 9 2026 2603.08844v1
Structured Schemas for LLM-Modeler Collaboration in Quantitative Systems Pharmacology Model Calibration

Quantitative systems pharmacology (QSP) models require calibration data from published literature, yet manual curation produces inconsistent documenta...

Longitudinal NSCLC Treatment Progression via Multimodal Generative Models

Predicting tumor evolution during radiotherapy is a clinically critical challenge, particularly when longitudinal changes are driven by both anatomy a...

Mar 6 2026 2603.06147v1
AI End-to-End Radiation Treatment Planning Under One Second

Artificial intelligence-based radiation therapy (RT) planning has the potential to reduce planning time and inter-planner variability, improving effic...

Mar 6 2026 2603.06338v1
Conversational Artificial Intelligence Agents-Enabled Dissection of RTK-RAS and MAPK Pathway Dependencies in Gemcitabine-Treated Pancreatic Ductal Adenocarcinoma (PDAC)

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy characterized by profound molecular heterogeneity and inconsistent responses to ge...

TC-SSA: Token Compression via Semantic Slot Aggregation for Gigapixel Pathology Reasoning

The application of large vision-language models to computational pathology holds great promise for diagnostic assistants but faces a critical computat...

Mar 1 2026 2603.01143v1
CT-based Automated Volumetry as a Biomarker of Global and Split Renal Function in Living Kidney Donors

Background: Kidney volumetry derived from CT has been proposed as a surrogate of renal function in living kidney donor evaluation. However, clinical i...

Inference of cancer driver mutations from tumor microenvironmentcomposition: a pan-cancer study with cross-platform external validation

Cancer driver mutations shape the tumor microenvironment (TME), yet whether TME composition alone can predict genotype has not been systematically eva...

IPv2: An Improved Image Purification Strategy for Real-World Ultra-Low-Dose Lung CT Denoising

The image purification strategy constructs an intermediate distribution with aligned anatomical structures, which effectively corrects the spatial mis...

Feb 22 2026 2602.19314v1
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