Oncology/Hematology

Lung Cancer

Latest AI and machine learning research in lung cancer for healthcare professionals.

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Showing 241-260 of 10,079 articles

Multi-omics investigation of per- and polyfluoroalkyl substances in lung adenocarcinoma: comprehensive network toxicology, machine learning and molecular docking experiments.

Growing concerns regarding per- and polyfluoroalkyl substances (PFAS) as pervasive environmental contaminants have prompted increasing scrutiny regarding their potential contributions to pulmonary diseases. Therefore, this study specifically investigates their implications in lung adenocarcinoma (LUAD) pathogenesis. We utilized the Comparative Toxicogenomics Database (CTD), GeneCards, and OMIM dat...

Jun 23 2026 42334505

Metabolic pathway signatures define prognostic subtypes of lung adenocarcinoma.

Metabolic reprogramming is a core hallmark of cancer, yet how it contributes to the clinical heterogeneity of lung adenocarcinoma (LUAD) remains poorly understood. Here, by applying unsupervised clustering to the metabolic transcriptomes of 510 LUAD tumours, we identify two robust and prognostically significant subtypes. We show that these subtypes have divergent clinical outcomes, with subtype-1 ...

Jun 23 2026 42337154
Population pharmacokinetics of dalbavancin: external validation, model averaging, and implications for precision dosing in prolonged therapy.

Dalbavancin is increasingly used off-label for prolonged therapy in gram-positive infections, but optimal repeat-dosing strategies remain undefined, a...

Jun 22 2026 42363831
A highly interpretable machine learning model for predicting lung cancer bone metastasis: uncovering the synergistic effect of routine biochemical markers.

BACKGROUND: Bone metastasis (BM) significantly impairs lung cancer prognosis and patient quality of life. Conventional imaging modalities often face l...

Jun 22 2026 42329565
Radiation shielding and microstructural characteristics of nano-silica and nano-alumina modified cement composites.

The increasing use of nuclear technology in medicine, industry, and energy requires effective durable radiation shielding. This study aimed to develop...

Jun 22 2026 42331888
Handling missing modalities in multimodal survival prediction for non-small cell lung cancer.

Accurate survival prediction in non-small cell lung cancer (NSCLC) requires integrating clinical, radiological, and histopathological data. Multimodal...

Jun 22 2026 42332139
Detection of rheumatoid arthritis-associated interstitial lung disease: a systematic review and meta-analysis.

BACKGROUND: Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) often has an insidious onset with few or no respiratory symptoms, so ea...

Jun 22 2026 42324528
Association between dynamic digital radiography findings and post-extubation respiratory deterioration: A retrospective exploratory analysis of a prospectively collected ICU cohort.

INTRODUCTION: Dynamic Digital Radiography (DDR) is a novel bedside imaging modality that enables real-time visualization of pulmonary motion with mini...

Jun 22 2026 42329910
Extracellular vesicles as diagnostic and prognostic biomarkers in non-small cell lung Cancer.

INTRODUCTION: Non-small cell lung cancer (NSCLC) remains the leading cause of cancer-related mortality worldwide, largely due to late-stage diagnosis ...

Jun 21 2026 42323710
Single-cell and multi-omics integration delineates the landscape of gene-wise intratumor heterogeneity and identifies prognostic biomarkers for immunotherapy in non-small cell lung cancer.

BACKGROUND: Gene-wise intratumor heterogeneity (ITH), defined as spatial variability in the expression of individual genes across tumor regions, remai...

Jun 20 2026 42322411
A HRH1-YAP1 feedback loop drives pancreatic cancer progression and predicts therapeutic response.

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy with a dismal prognosis, characterized by an immunosuppressive tumor microenviro...

Jun 19 2026 42383289
Decoding chromatin regulator-LAIR1+ M2 like macrophage patterns in atherosclerosis and clinical outcomes of Lung adenocarcinoma patients: evidence from artificial intelligence-driven multi omics and in vitro validation.

Atherosclerosis (AS) is a common complication of lung adenocarcinoma (LUAD), but its underlying mechanisms in LUAD remain unclear. This study aimed to...

Jun 19 2026 42319401
Latent twins: a framework for scene recognition and fast radiative transfer inversion in FORUM all-sky observations.

The FORUM (Far-infrared Outgoing Radiation Understanding and Monitoring) mission will provide, for the first time, systematic far-infrared spectral me...

Jun 19 2026 42321322
Identifying predictive hematological biomarkers for radiation exposure by machine learning in mouse models.

BACKGROUND: Population-scale radiation exposure assessment during radiological emergencies is hindered by the slow and costly nature of current method...

Jun 19 2026 42321393
Pancreatic organoids and organoid-on-a-chip platforms: from disease modeling to precision therapy.

BACKGROUND: Pancreatic diseases, including diabetes, pancreatic ductal adenocarcinoma, pancreatitis, and cystic fibrosis, impose a substantial clinica...

Jun 19 2026 42321786
Machine learning-driven QSAR modeling combined with single cell transcriptomics identifies novel drug targets for lung cancer.

BACKGROUND: Non-small cell lung cancer (NSCLC) is a leading cause of cancer-related mortality, largely due to frequent metastasis to the brain and bon...

Jun 19 2026 42321836
Frontiers in Raman nano-diagnostics: SERS and TERS of extracellular vesicles for cancer detection.

Efforts to create rapid, non-invasive, and reliable cancer diagnostics have increasingly focused on extracellular vesicles (EVs), nanoscale carriers o...

Jun 18 2026 42312929
Deep Learning of CT Imaging Predicts PD-L1 Expression and Immunotherapy Response in Metastatic NSCLC: A Multi-Center Study.

Immune checkpoint inhibitors (ICIs) benefit only a subset of patients with metastatic non-small cell lung cancer (NSCLC), but current selection relies...

Jun 18 2026 42314966
[Reirradiation: A new therapeutic paradigm in oncology].

Reirradiation (reRT) has become an essential therapeutic option for selected patients with locoregional recurrences, when surgery or systemic therapie...

Jun 18 2026 42315464
Deep integration of clinical metadata with [18F]FDG PET/CT imaging for histological subtyping in non-small cell lung cancer: a multi-center study.

PURPOSE: To develop and validate a multimodal deep learning framework that integrates clinical metadata with [18F]FDG PET/CT imaging to resolve overla...

Jun 18 2026 42310216
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