Lung Cancer

Deep Learning-driven Microfluidic-SERS to Characterize the Heterogeneity in Exosomes for Classifying Non-Small Cell Lung Cancer Subtypes.

Lung cancer exhibits strong heterogeneity, and its early diagnosis and precise subtyping are of great importance, as they can increase the ability to deliver personalized medicines by tailoring therapy regimens. Tissue biopsy, albeit the gold standard, is invasive, costly and provides limited information about the tumor and its molecular landscape. Exosomes, as promising biomarkers for lung cancer...

Feasibility and Impact of a Radiation Therapy Technologist-Driven Workflow for Cone Beam Computed Tomography Guided Partial Breast Adaptive Radiation Therapy.

PURPOSE: Cone beam computed tomography-based online adaptive radiation therapy (ART) allows significantly smaller planning target volume margins for patients treated with adaptive stereotactic partial breast irradiation. However, this approach places increased demands on the treatment team, particularly physicians. We hypothesize that with appropriate training, physicians' involvement at the treat...

Taking the 3Rs to a higher level: replacement and reduction of animal testing in life sciences in space research.

Human settlements on the Moon, crewed missions to Mars and space tourism will become a reality in the next few decades. Human presence in space, espec...

Predicting a failure of postoperative thromboprophylaxis in non-small cell lung cancer: A stacking machine learning approach.

BACKGROUND: Non-small-cell lung cancer (NSCLC) and its surgery significantly increase the venous thromboembolism (VTE) risk. This study explored the V...

Anticancer drug response prediction integrating multi-omics pathway-based difference features and multiple deep learning techniques.

Individualized prediction of cancer drug sensitivity is of vital importance in precision medicine. While numerous predictive methodologies for cancer ...

Internal Target Volume Estimation for Liver Cancer Radiation Therapy Using an Ultra Quality 4-Dimensional Magnetic Resonance Imaging.

PURPOSE: Accurate internal target volume (ITV) estimation is essential for effective and safe radiation therapy in liver cancer. This study evaluates ...

Decision tree-based machine learning algorithm for prediction of acute radiation esophagitis.

BACKGROUND: Radiation-induced esophagitis remains a significant challenge in thoracic and neck cancer treatment, impacting patient quality of life and...

Deep Learning-Based Auto-Segmentation for Liver Yttrium-90 Selective Internal Radiation Therapy.

The aim was to evaluate a deep learning-based auto-segmentation method for liver delineation in Y-90 selective internal radiation therapy (SIRT). A de...

Control of dental calculus Prevents severe Radiation-Induced oral mucositis in patients undergoing radiotherapy for nasopharyngeal carcinoma.

PURPOSE: This study aims to develop an artificial intelligence model to predict severe radiation-induced oral mucositis (RIOM) in patients with locall...

The Role of Eosinophils, Eosinophil-Related Cytokines and AI in Predicting Immunotherapy Efficacy in NSCLC Cancer.

Immunotherapy and chemoimmunotherapy are standard treatments for non-oncogene-addicted advanced non-small cell lung cancer (NSCLC). Currently, a limit...

Lung cancer detection and classification using optimized CNN features and Squeeze-Inception-ResNeXt model.

Lung cancer, with its high mortality rate, is one of the deadliest diseases globally. The alarming increase in lung cancer deaths and its widespread p...

Preoperative Prediction of STAS Risk in Primary Lung Adenocarcinoma Using Machine Learning: An Interpretable Model with SHAP Analysis.

BACKGROUND: Accurate preoperative prediction of spread through air spaces (STAS) in primary lung adenocarcinoma (LUAD) is critical for optimizing surg...

Optimizing imaging modalities for sarcoma subtypes in radiation therapy: State of the art.

The choice of imaging modalities is essential in sarcoma management, as different techniques provide complementary information depending on tumor subt...

Precision Oncology in Non-small Cell Lung Cancer: A Comparative Study of Contextualized ChatGPT Models.

OBJECTIVES: The growing adoption of Large Language Models (LLMs) in medicine has raised important questions about their potential utility for clinical...

A tumor-infiltrating B lymphocytes -related index based on machine-learning predicts prognosis and immunotherapy response in lung adenocarcinoma.

INTRODUCTION: Tumor-infiltrating B lymphocytes (TILBs) play a pivotal role in shaping the immune microenvironment of tumors (TIME) and in the progress...

Automated classification of tertiary lymphoid structures in colorectal cancer using TLS-PAT artificial intelligence tool.

Colorectal cancer (CRC) ranks as the third most common and second deadliest cancer worldwide. The immune system, particularly tertiary lymphoid struct...

Development of PDAC diagnosis and prognosis evaluation models based on machine learning.

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is difficult to detect early and highly aggressive, often leading to poor patient prognosis. Exist...

Nanomaterial-Based Molecular Imaging in Cancer: Advances in Simulation and AI Integration.

Nanomaterials represent an innovation in cancer imaging by offering enhanced contrast, improved targeting capabilities, and multifunctional imaging mo...

American College of Veterinary Radiology and European College of Veterinary Diagnostic Imaging position statement on artificial intelligence.

The American College of Veterinary Radiology (ACVR) and the European College of Veterinary Diagnostic Imaging (ECVDI) recognize the transformative pot...

Stroma and lymphocytes identified by deep learning are independent predictors for survival in pancreatic cancer.

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers known to humans. However, not all patients fare equally poor survival, and a...