Lung Cancer

Machine learning models reveal ARHGAP11A's impact on lymph node metastasis and stemness in NSCLC.

Most patients with non-small cell lung cancer (NSCLC) are diagnosed at an advanced stage of the disease, which complicates treatment due to a heightened risk of metastasis. Consequently, the timely identification of biomarkers associated with lymph node metastasis is essential for improving the clinical management of NSCLC patients. In this research, the WGCNA algorithm was utilized to pinpoint ge...

Construction of a combined prognostic model for pancreatic ductal adenocarcinoma based on deep learning and digital pathology images.

BACKGROUND: Deep learning has made significant advancements in the field of digital pathology, and the integration of multiple models has further improved accuracy. In this study, we aimed to construct a combined prognostic model using deep learning-extracted features from digital pathology images of pancreatic ductal adenocarcinoma (PDAC) alongside clinical predictive indicators and to explore it...

Diagnosis of Pancreatic Ductal Adenocarcinoma Using Deep Learning.

Recent advances in artificial intelligence (AI) research, particularly in image processing technologies, have shown promising applications across vari...

Topic-sentiment analysis of citizen environmental complaints in China: Using a Stacking-BERT model.

Environmental complaints serve as a crucial means for citizens to participate in environmental regulation, providing precise insights for real-time id...

Quantitative analysis of imaging characteristics in lung adenocarcinoma in situ using artificial intelligence.

BACKGROUND: With the rising incidence of pulmonary nodules (PNs), lung adenocarcinoma in situ (AIS) is a critical early stage of lung cancer, necessit...

Comprehensive multi-omics analysis identifies chromatin regulator-related signatures and TFF1 as a therapeutic target in lung adenocarcinoma through a 429-combination machine learning approach.

INTRODUCTION: Lung cancer is a leading cause of cancer-related deaths, with its incidence continuing to rise. Chromatin remodeling, a crucial process ...

Advancements in early detection of pancreatic cancer: the role of artificial intelligence and novel imaging techniques.

Early detection is crucial for improving survival rates of pancreatic ductal adenocarcinoma (PDA), yet current diagnostic methods can often fail at th...

Prediction of hepatocellular carcinoma response to radiation segmentectomy using an MRI-based machine learning approach.

PURPOSE: To evaluate the value of pre-treatment MRI-based radiomics in patients with hepatocellular carcinoma (HCC) for the prediction of response to ...

Deep learning analysis of histopathological images predicts immunotherapy prognosis and reveals tumour microenvironment features in non-small cell lung cancer.

BACKGROUND: Non-small cell lung cancer (NSCLC) is one of the leading causes of cancer mortality worldwide. Immune checkpoint inhibitors (ICIs) have em...

Screening of BindingDB database ligands against EGFR, HER2, Estrogen, Progesterone and NF-κB receptors based on machine learning and molecular docking.

Breast cancer, the second most prevalent cancer among women worldwide, necessitates the exploration of novel therapeutic approaches. To target the fou...

Key genes and pathways in the molecular landscape of pancreatic ductal adenocarcinoma: A bioinformatics and machine learning study.

Pancreatic ductal adenocarcinoma (PDAC) is recognized for its aggressive nature, dismal prognosis, and a notably low five-year survival rate, undersco...

The SINFONIA project repository for AI-based algorithms and health data.

The SINFONIA project's main objective is to develop novel methodologies and tools that will provide a comprehensive risk appraisal for detrimental eff...

Optimization and correction of breast dynamic optical imaging projection data based on deep learning.

Breast cancer poses a significant health threat to women, necessitating advancements in diagnostic technologies. Breast dynamic optical imaging (DOI) ...

Deep Learning-Based Estimation of Radiographic Position to Automatically Set Up the X-Ray Prime Factors.

Radiation dose and image quality in radiology are influenced by the X-ray prime factors: KVp, mAs, and source-detector distance. These parameters are ...

Artificial Intelligence-Driven Skin Aging Simulation as a Novel Skin Cancer Prevention.

INTRODUCTION: Skin cancer, a prevalent cancer type among fair-skinned patients globally, poses a relevant public health concern due to rising incidenc...

A Lightweight Method for Breast Cancer Detection Using Thermography Images with Optimized CNN Feature and Efficient Classification.

Breast cancer is a prominent cause of death among women worldwide. Infrared thermography, due to its cost-effectiveness and non-ionizing radiation, ha...

Deep Learning-Based Synthetic Computed Tomography for Low-Field Brain Magnetic Resonance-Guided Radiation Therapy.

PURPOSE: Magnetic resonance (MR)-guided radiation therapy enables online adaptation to address intra- and interfractional changes. To address the need...

Development of learning-based predictive models for radiation-induced atrial fibrillation in non-small cell lung cancer patients by integrating patient-specific clinical, dosimetry, and diagnostic information.

BACKGROUND AND PURPOSE: Radiotherapy (RT) in non-small cell lung cancer (NSCLC) can induce cardiac adverse events, including atrial fibrillation (AF),...

Preoperative markers for identifying CT ≤2 cm solid nodules of lung adenocarcinoma based on image deep learning.

BACKGROUND: The solid pattern is a highly malignant subtype of lung adenocarcinoma. In the current era of transitioning from lobectomy to sublobar res...

A vision transformer-based deep transfer learning nomogram for predicting lymph node metastasis in lung adenocarcinoma.

BACKGROUND: Lymph node metastasis (LNM) plays a crucial role in the management of lung cancer; however, the ability of chest computed tomography (CT) ...