Lung Cancer

Dual scope method: A novel application of a simultaneous multi-image display system for a thoracoscopic robotic lobectomy.

The advantages of a multi-input display system platform in robotic thoracic surgery have not been well described. We report the novel application of a multi-display system for simultaneous visualization of an additional thoracoscopic image during a robotic lobectomy, which we have named the dual scope method. An additional thoracoscope is inserted from the bottom of the thoracic cavity. This thora...

Cancer-associated fibroblasts are associated with poor prognosis in solid type of lung adenocarcinoma in a machine learning analysis.

Cancer-associated fibroblasts (CAFs) participate in critical processes in the tumor microenvironment, such as extracellular matrix remodeling, reciprocal signaling interactions with cancer cells and crosstalk with infiltrating inflammatory cells. However, the relationships between CAFs and survival are not well known in lung cancer. The aim of this study was to reveal the correlations of CAFs with...

Comparative analysis of machine learning approaches to classify tumor mutation burden in lung adenocarcinoma using histopathology images.

Both histologic subtypes and tumor mutation burden (TMB) represent important biomarkers in lung cancer, with implications for patient prognosis and tr...

Deep learning-based gene selection in comprehensive gene analysis in pancreatic cancer.

The selection of genes that are important for obtaining gene expression data is challenging. Here, we developed a deep learning-based feature selectio...

Diagnostic performance and image quality of deep learning image reconstruction (DLIR) on unenhanced low-dose abdominal CT for urolithiasis.

BACKGROUND: Patients with urolithiasis undergo radiation overexposure from computed tomography (CT) scans. Improvement of image reconstruction is nece...

Deep learning and lung ultrasound for Covid-19 pneumonia detection and severity classification.

The Covid-19 European outbreak in February 2020 has challenged the world's health systems, eliciting an urgent need for effective and highly reliable ...

Resolution-based distillation for efficient histology image classification.

Developing deep learning models to analyze histology images has been computationally challenging, as the massive size of the images causes excessive s...

Applications of machine and deep learning to patient-specific IMRT/VMAT quality assurance.

In order to deliver accurate and safe treatment to cancer patients in radiation therapy using advanced techniques such as intensity modulated radiatio...

Simultaneous Recognition of Atrophic Gastritis and Intestinal Metaplasia on White Light Endoscopic Images Based on Convolutional Neural Networks: A Multicenter Study.

INTRODUCTION: Patients with atrophic gastritis (AG) or gastric intestinal metaplasia (GIM) have elevated risk of gastric adenocarcinoma. Endoscopic sc...

Deep learning for segmentation in radiation therapy planning: a review.

Segmentation of organs and structures, as either targets or organs-at-risk, has a significant influence on the success of radiation therapy. Manual se...

Colorectal cancer surgery: by Cambridge Medical Robotics Versius Surgical Robot System-a single-institution study. Our experience.

With the previous experiences in performing laparoscopic for over a period of 15 years and da Vinci colorectal surgeries from 2010 to 2013, we started...

Semi-supervised training of deep convolutional neural networks with heterogeneous data and few local annotations: An experiment on prostate histopathology image classification.

Convolutional neural networks (CNNs) are state-of-the-art computer vision techniques for various tasks, particularly for image classification. However...

Multi-institutional development and external validation of machine learning-based models to predict relapse risk of pancreatic ductal adenocarcinoma after radical resection.

BACKGROUND: Surgical resection is the only potentially curative treatment for pancreatic ductal adenocarcinoma (PDAC) and the survival of patients aft...

Quantitative Analysis and Automated Lung Ultrasound Scoring for Evaluating COVID-19 Pneumonia With Neural Networks.

As being radiation-free, portable, and capable of repetitive use, ultrasonography is playing an important role in diagnosing and evaluating the COVID-...

Unsupervised water scene dehazing network using multiple scattering model.

In water scenes, where hazy images are subject to multiple scattering and where ideal data sets are difficult to collect, many dehazing methods are no...

Clinical decision support algorithm based on machine learning to assess the clinical response to anti-programmed death-1 therapy in patients with non-small-cell lung cancer.

OBJECTIVE: Anti-programmed death (PD)-1 therapy confers sustainable clinical benefits for patients with non-small-cell lung cancer (NSCLC), but only s...

Artificial intelligence in medical imaging: implications for patient radiation safety.

Artificial intelligence, including deep learning, is currently revolutionising the field of medical imaging, with far reaching implications for almost...

A hierarchical deep reinforcement learning framework for intelligent automatic treatment planning of prostate cancer intensity modulated radiation therapy.

We have previously proposed an intelligent automatic treatment planning (IATP) framework that builds a virtual treatment planner network (VTPN) to ope...

Technical Note: Dose prediction for head and neck radiotherapy using a three-dimensional dense dilated U-net architecture.

PURPOSE: Radiation therapy treatment planning is a time-consuming and iterative manual process. Consequently, plan quality varies greatly between and ...

Label-free classification of dead and live colonic adenocarcinoma cells based on 2D light scattering and deep learning analysis.

The measurement of cell viability plays an essential role in the area of cell biology. At present, the common methods for cell viability assay mainly ...