Lung Cancer

Enhancing digital tomosynthesis (DTS) for lung radiotherapy guidance using patient-specific deep learning model.

Digital tomosynthesis (DTS) has been proposed as a fast low-dose imaging technique for image-guided radiation therapy (IGRT). However, due to the limited scanning angle, DTS reconstructed by the conventional FDK method suffers from significant distortions and poor plane-to-plane resolutions without full volumetric information, which severely limits its capability for image guidance. Although exist...

A semantic database for integrated management of image and dosimetric data in low radiation dose research in medical imaging.

Medical ionizing radiation procedures and especially medical imaging are a non negligible source of exposure to patients. Whereas the biological effects of high absorbed doses are relatively well known, the effects of low absorbed doses are still debated. This work presents the development of a computer platform called Image and Radiation Dose BioBank (IRDBB) to manage research data produced in th...

Solar radiation prediction using boosted decision tree regression model: A case study in Malaysia.

Reliable and accurate prediction model capturing the changes in solar radiation is essential in the power generation and renewable carbon-free energy ...

High performance in risk stratification of intraductal papillary mucinous neoplasms by confocal laser endomicroscopy image analysis with convolutional neural networks (with video).

BACKGROUND AND AIMS: EUS-guided needle-based confocal laser endomicroscopy (EUS-nCLE) can differentiate high-grade dysplasia/adenocarcinoma (HGD-Ca) i...

Real-time liver tracking algorithm based on LSTM and SVR networks for use in surface-guided radiation therapy.

BACKGROUND: Surface-guided radiation therapy can be used to continuously monitor a patient's surface motions during radiotherapy by a non-irradiating,...

Improving prognostic performance in resectable pancreatic ductal adenocarcinoma using radiomics and deep learning features fusion in CT images.

As an analytic pipeline for quantitative imaging feature extraction and analysis, radiomics has grown rapidly in the past decade. On the other hand, r...

DaNet: dose-aware network embedded with dose-level estimation for low-dose CT imaging.

Many deep learning (DL)-based image restoration methods for low-dose CT (LDCT) problems directly employ the end-to-end networks on low-dose training d...

Performance of deep learning synthetic CTs for MR-only brain radiation therapy.

PURPOSE: To evaluate the dosimetric and image-guided radiation therapy (IGRT) performance of a novel generative adversarial network (GAN) generated sy...

Lung cancer histology classification from CT images based on radiomics and deep learning models.

Adenocarcinoma (AC) and squamous cell carcinoma (SCC) are frequent reported cases of non-small cell lung cancer (NSCLC), responsible for a large fract...

Diagnostic value of deep learning reconstruction for radiation dose reduction at abdominal ultra-high-resolution CT.

OBJECTIVES: We evaluated lower dose (LD) hepatic dynamic ultra-high-resolution computed tomography (U-HRCT) images reconstructed with deep learning re...

Fully end-to-end deep-learning-based diagnosis of pancreatic tumors.

Artificial intelligence can facilitate clinical decision making by considering massive amounts of medical imaging data. Various algorithms have been i...

Assessing PD-L1 expression in non-small cell lung cancer and predicting responses to immune checkpoint inhibitors using deep learning on computed tomography images.

This study aimed to use computed tomography (CT) images to assess PD-L1 expression in non-small cell lung cancer (NSCLC) and predict response to immu...

Pure and Hybrid Deep Learning Models can Predict Pathologic Tumor Response to Neoadjuvant Therapy in Pancreatic Adenocarcinoma: A Pilot Study.

BACKGROUND: Neoadjuvant therapy may improve survival of patients with pancreatic adenocarcinoma; however, determining response to therapy is difficult...

The minimum-mortality estimated glomerular filtration rate percentile shifts upward in the aged population: a nationwide population-based study.

BACKGROUND: The estimated glomerular filtration rate (eGFR) is a biomarker not only for kidney function, but also for major clinical outcomes. We aime...

A CT-Based Automated Algorithm for Airway Segmentation Using Freeze-and-Grow Propagation and Deep Learning.

Chronic obstructive pulmonary disease (COPD) is a common lung disease, and quantitative CT-based bronchial phenotypes are of increasing interest as a ...

Data-driven dose calculation algorithm based on deep U-Net.

Accurate and efficient dose calculation is an important prerequisite to ensure the success of radiation therapy. However, all the dose calculation alg...

Feasibility of automated planning for whole-brain radiation therapy using deep learning.

PURPOSE: The purpose of this study was to develop automated planning for whole-brain radiation therapy (WBRT) using a U-net-based deep-learning model ...

A physics-guided modular deep-learning based automated framework for tumor segmentation in PET.

An important need exists for reliable positron emission tomography (PET) tumor-segmentation methods for tasks such as PET-based radiation-therapy plan...

Deep learning-based real-time volumetric imaging for lung stereotactic body radiation therapy: a proof of concept study.

Due to the inter- and intra- variation of respiratory motion, it is highly desired to provide real-time volumetric images during the treatment deliver...

Denoising Autoencoder, A Deep Learning Algorithm, Aids the Identification of A Novel Molecular Signature of Lung Adenocarcinoma.

Precise biomarker development is a key step in disease management. However, most of the published biomarkers were derived from a relatively small numb...