Hematology

Lymphoma

Latest AI and machine learning research in lymphoma for healthcare professionals.

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Showing 1241-1260 of 7,143 articles

Longitudinal Boundary Sharpness Coefficient Slopes Predict Time to Alzheimer's Disease Conversion in Mild Cognitive Impairment: A Survival Analysis Using the ADNI Cohort

Predicting whether someone with mild cognitive impairment (MCI) will progress to Alzheimer's disease (AD) is crucial in the early stages of neurodegeneration. This uncertainty limits enrollment in clinical trials and delays urgent treatment. The Boundary Sharpness Coefficient (BSC) measures how well-defined the gray-white matter boundary looks on structural MRI. This study measures how BSC changes...

Mar 27 2026 2603.26007v1

6D Robotic OCT Scanning of Curved Tissue Surfaces

Optical coherence tomography (OCT) is a non-invasive volumetric imaging modality with high spatial and temporal resolution. For imaging larger tissue structures, OCT probes need to be moved to scan the respective area. For handheld scanning, stitching of the acquired OCT volumes requires overlap to register the images. For robotic scanning and stitching, a typical approach is to restrict the motio...

Mar 23 2026 2603.22012v1
X-Cell: Scaling Causal Perturbation Prediction Across Diverse Cellular Contexts via Diffusion Language Models

Causal models of cellular systems hold the promise to empower broad biological discovery, including the systematic identification of novel targets for...

A Cross-Study Multi-Organ Cell Atlas ofMacaca fascicularis Informed by Human Foundation Model Annotation: A Resource for Translational Target Assessment

Non-human primates (NHPs), particularly Macaca fascicularis (cynomolgus macaque), represent an essential model for preclinical assessment of biologics...

SF-Mamba: Rethinking State Space Model for Vision

The realm of Mamba for vision has been advanced in recent years to strike for the alternatives of Vision Transformers (ViTs) that suffer from the quad...

Mar 17 2026 2603.16423v1
Understanding Cell Fate Decisions with Temporal Attention

Understanding non-genetic determinants of cell fate is critical for developing and improving cancer therapies, as genetically identical cells can exhi...

Mar 17 2026 2603.16562v1
An explainable boosting machine model for identifying artifacts caused by formalin-fixed paraffin embedding

Background: Formalin-fixed paraffin-embedding (FFPE) is a widely used, cost-effective method for long-term storage of clinical samples. However, fixat...

Accelerating Stroke MRI with Diffusion Probabilistic Models through Large-Scale Pre-training and Target-Specific Fine-Tuning

Purpose: To develop a data-efficient strategy for accelerated MRI reconstruction with Diffusion Probabilistic Generative Models (DPMs) that enables fa...

Mar 13 2026 2603.13007v1
Computed atlas of the human GPCR-G protein signaling complexes

Experimental mapping of G protein-coupled receptors (GPCR)-G protein signaling coupling has illuminated hundreds of receptors, yet the coupling specif...

Conversational Artificial Intelligence-Enabled Molecular Characterization of Sezary Syndrome Reveals Distinct Pathway-Level Alterations Compared with Non-Sezary Cutaneous T-Cell Lymphoma

ABSTRACT Background: Sezary syndrome (SS) represents an aggressive leukemic variant of cutaneous T-cell lymphoma (CTCL) with distinct clinical behavio...

Experimental multi-center validation of a radiomics-based photonic quantum precision medicine architecture for lesion-level prediction of anti-PD-1 response in non-small cell lung cancer

Background: Previous research has shown that radiomics-based machine learning models are promising precision medicine tools for lesion-level predictio...

LLMsFold: Integrating Large Language Models and Biophysical Simulations for De Novo Drug Design

The discovery of novel small molecules is challenging because of the vastness of chemical space and the complexity of protein-ligand interactions, lea...

Parkinson's Disease motor and non-motor progression models emerge from pathway-level transcriptomics

Background Prognosis and therapeutic management in Parkinson's disease is a challenging task by its highly heterogeneous disease progression and sympt...

Towards Translational Sleep Staging: A Cross-Species Deep-Learning Model for Rodent and Human EEG

Study Objectives Automated sleep staging underpins clinical sleep assessment and translational neuroscience, yet most data analyses work addresses hum...

An automatic counting algorithm for the quantification and uncertainty analysis of the number of microglial cells trainable in small and heterogeneous datasets

Counting immunopositive cells on biological tissues generally requires either manual annotation or (when available) automatic rough systems, for scann...

Feb 26 2026 2602.22974v1
A Framework for Cross-Domain Generalization in Coronary Artery Calcium Scoring Across Gated and Non-Gated Computed Tomography

Coronary artery calcium (CAC) scoring is a key predictor of cardiovascular risk, but it relies on ECG-gated CT scans, restricting its use to specializ...

Feb 25 2026 2602.21935v1
Spatial multi-omics identify an immunosuppressive lipid-laden macrophage niche in primary CNS lymphoma

Primary central nervous system lymphoma (PCNSL) is a subtype of diffuse large B-cell lymphoma (DLBCL) with confined CNS growth. We evaluated tumor mic...

Context-aware Skin Cancer Epithelial Cell Classification with Scalable Graph Transformers

Whole-slide images (WSIs) from cancer patients contain rich information that can be used for medical diagnosis or to follow treatment progress. To aut...

Feb 17 2026 2602.15783v1
Identifying Reasons for ACEI/ARB Non-Use in CKD Using Scalable Clinical NLP with Schema-Guided LLM Augmentation

IMPORTANCE: Although angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are recommended for people with chronic...

Fully-automated sleep staging: multicenter validation of a generalizable deep neural network for Parkinson's disease and isolated REM sleep behavior disorder

Isolated REM sleep behavior disorder (iRBD) is a key prodromal marker of Parkinson's disease (PD), and video-polysomnography (vPSG) remains the diagno...

Feb 10 2026 2602.09793v2
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