Metabolic Syndrome

Non-invasive ML methods for diagnosis of congenital heart disease associated with pulmonary arterial hypertension.

OBJECTIVE: Congenital heart disease with pulmonary arterial hypertension (CHD-PAH), caused by CHD, is associated with high clinical mortality. Hence, timely diagnosis is imperative for treatment.

Web application using machine learning to predict cardiovascular disease and hypertension in mine workers.

This study presents a web application for predicting cardiovascular disease (CVD) and hypertension (HTN) among mine workers using machine learning (ML) techniques. The dataset, collected from 699 participants at the Gol-Gohar mine in Iran between 2016 and 2020, includes demographic, occupational, lifestyle, and medical information. After preprocessing and feature engineering, the Random Forest alg...

Estimating cardiovascular mortality in patients with hypertension using machine learning: The role of depression classification based on lifestyle and physical activity.

PURPOSE: This study aims to harness machine learning techniques, particularly the Random Survival Forest (RSF) model, to assess the impact of depressi...

A comprehensive and bias-free machine learning approach for risk prediction of preeclampsia with severe features in a nulliparous study cohort.

Preeclampsia is one of the leading causes of maternal morbidity, with consequences during and after pregnancy. Because of its diverse clinical present...

Adipsin and Leptin Levels in Type 2 Diabetic Patients on Sitagliptin and Metformin Versus Metformin Therapy.

OBJECTIVES: Adipsin and leptin are adipokines that link adipose tissue dysfunction and increased fat accumulation to obesity-related metabolic disorde...

Optimizing hypertension prediction using ensemble learning approaches.

Hypertension (HTN) prediction is critical for effective preventive healthcare strategies. This study investigates how well ensemble learning technique...

Inhibition of the polyol pathway by extract: plausible implications for diabetic retinopathy treatment.

INTRODUCTION: Diabetic retinopathy is a significant microvascular disorder and the leading cause of vision impairment in working-age individuals. Hype...

Predicting dyslipidemia in Chinese elderly adults using dietary behaviours and machine learning algorithms.

OBJECTIVES: We aimed to predict dyslipidemia risk in elderly Chinese adults using machine learning and dietary analysis for public health.

Exploring the prognostic impact of triglyceride-glucose index in critically ill patients with first-ever stroke: insights from traditional methods and machine learning-based mortality prediction.

BACKGROUND: The incidence and mortality of first-ever strokes have risen sharply, especially in the intensive care unit (ICU). Emerging surrogate for ...

Investigating the anti-obesity potential of leaf bioactive compounds through machine learning and computational biology methods.

Obesity, a growing global health concern, is linked to severe ailments such as cardiovascular diseases, type 2 diabetes, cancer, and neuropsychiatric ...

Potential shared mechanisms in atopic dermatitis and type 2 diabetes identified via transcriptomic and machine learning approaches.

Although atopic dermatitis (AD) and type 2 diabetes mellitus (T2DM) may appear clinically and pathophysiologically unrelated, AD is a common skin dise...

Genotype-negative multiple endocrine neoplasia type 1 with prolactinoma, hyperparathyroidism, and subclinical Cushing's syndrome accompanied by hyperglycemia: a case report.

BACKGROUND: Multiple endocrine neoplasia type 1 (MEN1) is a rare autosomal dominant disorder, accompanied by multiple endocrine neoplasms of the parat...

Integrating AI-driven wearable devices and biometric data into stroke risk assessment: A review of opportunities and challenges.

Stroke is a leading cause of morbidity and mortality worldwide, and early detection of risk factors is critical for prevention and improved outcomes. ...

Revolutionary drug repositioning: the preventive and therapeutic potential of metformin and other antidiabetic drugs in age-related macular degeneration.

Age-related macular degeneration (AMD) is a leading cause of blindness among the elderly worldwide. Anti-vascular endothelial growth factor (anti-VEGF...

Machine learning evaluation of a hypertension screening program in a university workforce over five years.

The global prevalence of hypertension continues excessively elevated, especially among low- and middle-income nations. Workplaces provide tremendous o...

Discovering geroprotectors through the explainable artificial intelligence-based platform AgeXtend.

Aging involves metabolic changes that lead to reduced cellular fitness, yet the role of many metabolites in aging is unclear. Understanding the mechan...

Identification of an immune-related gene panel for the diagnosis of pulmonary arterial hypertension using bioinformatics and machine learning.

OBJECTIVE: This study aimed to screen an immune-related gene (IRG) panel and develop a novel approach for diagnosing pulmonary arterial hypertension (...

Antihypertensive Drug Recommendations for Reducing Arterial Stiffness in Patients With Hypertension: Machine Learning-Based Multicohort (RIGIPREV) Study.

BACKGROUND: High systolic blood pressure is one of the leading global risk factors for mortality, contributing significantly to cardiovascular disease...

Machine learning for predicting in-hospital mortality in elderly patients with heart failure combined with hypertension: a multicenter retrospective study.

BACKGROUND: Heart failure combined with hypertension is a major contributor for elderly patients (≥ 65 years) to in-hospital mortality. However, there...

Deep Learning to Detect Pulmonary Hypertension from the Chest X-Ray Images of Patients with Systemic Sclerosis.

Pulmonary hypertension (PH) is a serious prognostic complication in patients with systemic sclerosis (SSc). Deep learning models can be applied to det...