Nephrology

Latest AI and machine learning research in nephrology for healthcare professionals.

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Does size matter? Kidney transplant donor size determines kidney function among living donors.

BACKGROUND: Kidney donor outcomes are gaining attention, particularly as donor eligibility criteria continue to expand. Kidney size, a useful predictor of recipient kidney function, also likely correlates with donor outcomes. Although donor evaluation includes donor kidney size measurements, the association between kidney size and outcomes are poorly defined.

Oct 4 2016 28638611

A LASSO Method to Identify Protein Signature Predicting Post-transplant Renal Graft Survival.

Identifying novel biomarkers to predict renal graft survival is important in post-transplant clinical practice. Serum creatinine, currently the most popular surrogate biomarker, offers limited information of the underlying allograft profiles. It is known to perform unsatisfactorily to predict renal function. In this paper, we apply a LASSO machine-learning algorithm in the Cox proportional hazards...

Oct 3 2016 29399205
Antithyroid drug-associated MPO-ANCA-positive tubulointerstitial nephritis in a type 2 diabetes patient: a case report.

A 54-year-old man diagnosed with type 2 diabetes and hyperthyroidism was prescribed propylthiouracil (PTU) after the patient developed hepatic dysfunc...

Oct 3 2016 28509121
Serum osteoprotegerin and renal function in the general population: the Tromsø Study.

BACKGROUND: Serum osteoprotegerin (OPG) is elevated in patients with chronic kidney disease (CKD) and increases with decreasing renal function. Howeve...

Oct 3 2016 28638603
Course of chronic kidney disease in French patients.

BACKGROUND: In 1998, a French survey showed that the referral of patients with chronic kidney disease to a nephrologist was delayed, resulting in many...

Sep 23 2016 28638607
Association of serum intact fibroblast growth factor 23 with left ventricular mass and different echocardiographic findings in patients on hemodialysis.

OBJECTIVES: To determine the association of fibroblast growth factor 23 (FGF23) with left ventricular hypertrophy (LVH) through the assessment of left...

Sep 23 2016 28191535
Knowledge Translation Interventions to Improve the Timing of Dialysis Initiation: Protocol for a Cluster Randomized Trial.

BACKGROUND: Early initiation of chronic dialysis (starting dialysis with higher vs lower kidney function) has risen rapidly in the past 2 decades in C...

Sep 14 2016 28270916
Automatic 3D liver location and segmentation via convolutional neural network and graph cut.

PURPOSE: Segmentation of the liver from abdominal computed tomography (CT) images is an essential step in some computer-assisted clinical intervention...

Sep 7 2016 27604760
Effect of extract on the phase and morphology of calcium oxalate crystals.

OBJECTIVE: Calcium oxalate crystals are found in majority of kidney stones with calcium oxalate monohydrate (COM) as one of the primary types of kidne...

Sep 3 2016 29387552
Impact of FGF23 level on calcium and phosphorus levels in post-renal transplantation.

The level of fibroblast growth factor 23 (FGF23) may be considered as a prognostic factor for assessing renal function in regulating components of ph...

Sep 3 2016 28497083
Assessment of the pharmacokinetics, removal rate of hemodialysis, and safety of lactulose in hemodialysis patients.

Lactulose is often used to treat hepatic encephalopathy or constipation, and also exhibits benefits to chronic renal insufficiency due to reduce nitro...

Aug 29 2016 28911627
Neuro-endocrine effects of aqueous extract of (Linn.) leaf in male Wistar rat model of cyclophosphamide-induced reproductive toxicity.

Cyclophosphamide (CP) is a widely used cytotoxic alkylating agent with antitumor and immunosuppressant properties that is associated with various form...

Aug 3 2016 28959584
Effect of cranberry () oligosaccharides on the formation of advanced glycation end-products.

The formation and accumulation of advanced glycation end-products (AGEs) are implicated in several chronic human illnesses including type-2 diabetes,...

Jun 16 2016 28649289
An international observational study suggests that artificial intelligence for clinical decision support optimizes anemia management in hemodialysis patients.

Managing anemia in hemodialysis patients can be challenging because of competing therapeutic targets and individual variability. Because therapy recom...

Jun 2 2016 27262365
Development of a compact continuum tubular robotic system for nasopharyngeal biopsy.

Traditional posterior nasopharyngeal biopsy using a flexible nasal endoscope has the risks of abrasion and injury to the nasal mucosa and thus causing...

May 18 2016 27230499
Serum Thiamine Values in End-Stage Renal Disease Patients under Maintenance Hemodialysis.

OBJECTIVE: Hemodialysis patients are prone to malnutrition because of diet or many uremic complications. The objective of this study is to determine w...

May 10 2016 27164172
A MULTICENTER, LONGITUDINAL, INTERVENTIONAL, DOUBLE BLIND RANDOMIZED CLINICAL TRIAL IN HEMATOPOIETIC CELL TRANSPLANT RECIPIENTS RESIDING IN REMOTE AREAS: LESSONS LEARNED FROM THE LATE CYTOMEGALOVIRUS PREVENTION TRIAL.

PURPOSE: The logistics of conducting double-blinded phase III clinical trials with participants residing in remote locations are complex. Here we desc...

May 5 2016 28184381
Persisting Hypocalcemia After Surgical Parathyroidectomy: The Differential Effectiveness of Calcium Citrate Versus Calcium Carbonate With Acid Suppression.

The effectiveness of oral calcium (Ca) may be contingent on a patient׳s factors beyond compliance, such as proton-pump inhibitor use and the choice of...

Apr 22 2016 28104108
Protective effect of ginsenosides Rk3 and Rh4 on cisplatin-induced acute kidney injury and .

BACKGROUND: Nephrotoxicity is the major side effect in cisplatin chemotherapy. Previously, we reported that the ginsenosides Rk3 and Rh4 reduced cispl...

Apr 6 2016 28701862
Prediction and detection models for acute kidney injury in hospitalized older adults.

BACKGROUND: Acute Kidney Injury (AKI) occurs in at least 5 % of hospitalized patients and can result in 40-70 % morbidity and mortality. Even followin...

Mar 29 2016 27025458
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