Nephrology

Latest AI and machine learning research in nephrology for healthcare professionals.

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Application of machine learning in the research progress of post-kidney transplant rejection.

Post-kidney transplant rejection is a critical factor influencing transplant success rates and the survival of transplanted organs. With the rapid advancement of artificial intelligence technologies, machine learning (ML) has emerged as a powerful data analysis tool, widely applied in the prediction, diagnosis, and mechanistic study of kidney transplant rejection. This mini-review systematically s...

Mar 18 2026 41607813

Protocol for a global electronic Delphi on integrating artificial intelligence into solid organ transplantation.

Artificial intelligence (AI) is increasingly recognized as a transformative force in the field of solid organ transplantation. From enhancing donor-recipient matching to predicting clinical risks and tailoring immunosuppressive therapy, AI has the potential to improve both operational efficiency and patient outcomes. Despite these advancements, the perspectives of transplant professionals - those ...

Mar 18 2026 41607824
Exosomes in diabetic kidney disease: pathogenesis, biomarker discovery, and emerging therapeutics-a comprehensive systematic review.

Diabetic kidney disease (DKD), characterized by progressive renal dysfunction, is a prevalent microvascular complication of diabetes mellitus and a le...

Mar 17 2026 41845912
BKDRP: a biological knowledge-driven approach for drug response prediction using multi-omics data in cancer cell lines.

BACKGROUND: Cancer heterogeneity results in patients with the same diagnosis responding differently to drugs, making treatments extremely challenging....

Mar 17 2026 41845230
Protective Effects of Riociguat Against Contrast-Induced Nephropathy: An Experimental and Machine Learning-Based Study in Rats.

Contrast-induced nephropathy (CIN) is an important cause of acute kidney injury following exposure to iodinated contrast media, and effective preventi...

Mar 17 2026 41845584
Development and Validation of a Machine Learning-Based Nomogram for Predicting Severe Pneumocystis jirovecii Pneumonia in Kidney Transplant Recipients.

BACKGROUND Pneumocystis jirovecii pneumonia (PJP) is a life-threatening opportunistic infection in kidney transplant recipients (KTRs). Early identifi...

Mar 17 2026 41840841
Tailoring Materials Design for Aqueous Energy Storage and Conversion through Electrochemical Reconstruction.

The growing demand for renewable energy has spurred the development of efficient electrochemical systems. Transition metal-based materials serve as ke...

Mar 17 2026 41843900
Minimally invasive spine surgery: current advantages, limitations, and future directions.

Minimally invasive spine surgery (MISS), supported by advancements in endoscopic systems, tubular retractors, lateral access corridors, image-guided n...

Mar 17 2026 41844062
Integrated molecular and clinical profiling of primary mitochondrial oxidative phosphorylation disorders in an Indian cohort: Insights from genetics, neuroimaging, and machine learning.

Primary mitochondrial disorders are clinically and genetically heterogeneous and remain underdiagnosed in resource-limited settings. We performed a re...

Mar 16 2026 41850596
Interpretable Multi-Modality Consensus QSAR Framework: Integrating Machine and Deep Learning for Enhanced Multi-Endpoint Toxicity Assessment.

Accurate toxicity assessment is essential for chemical safety, but experimental testing is costly, slow, and ethically constrained, motivating the ado...

Mar 16 2026 41839829
Deep learning-based identification of chronic pulmonary embolism on CTPA: a regional lung analysis using multiplanar MIP images.

OBJECTIVE: Chronic pulmonary embolism (CPE) and chronic thromboembolic pulmonary hypertension (CTEPH) are challenging to diagnose, with delayed detect...

Mar 16 2026 41838262
Machine Learning Prediction of Progression to Dialysis in Patients With Polycystic Kidney Disease: Population-Based Retrospective Cohort Study.

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD), characterized by progressive cyst growth and renal decline, is the leading genetic c...

Mar 16 2026 41838891
Assessing interstitial fibrosis and tubular atrophy in kidney biopsies artificial intelligence versus humans.

PURPOSE OF REVIEW: The degree to which computerized methods, such as artificial intelligence (AI), will aid in the assessment of kidney histopathology...

Mar 16 2026 41830415
Bioinspired hybrid optimisation and deep belief neural networks for early chronic kidney disease detection: an explainable clinical AI framework.

The early detection of chronic kidney disease (CKD) can lead to timely and appropriate clinical intervention. However, most CKD diagnostic systems rel...

Mar 15 2026 41834383
Protective Effect of the FOXO3 Gene in Cardiometabolic Disease in the CHAMP Cohort.

Recent findings from the Honolulu Heart Program cohort in Hawaii suggest a longevity-associated variant of FOXO3 may provide resilience against cardio...

Mar 15 2026 41837379
Clinic-first sepsis recognition in the ICU: a proteomics-guided, parsimonious model with independent validation.

BACKGROUND: Sepsis recognition in the ICU remains variable and relies on consensus clinical criteria rather than biomarker-defined rules. Routine labo...

Mar 14 2026 41832432
Integrative Approaches in Lung Cancer Diagnosis: Bridging Molecular Biomarkers and AI Driven Imaging.

Though critical, traditional diagnostic approaches such as X-ray, CT scans, bronchoscopy and tissue biopsy don't reliably detect lung cancer at early ...

Mar 14 2026 41830914
Advanced artificial intelligence vs simpler models for 1-year death prediction among patients receiving hemodialysis.

OBJECTIVES: We evaluated the data requirement for modern AI tools to outperform simpler models in predicting short-term mortality in over 500 000 pati...

Mar 13 2026 41873434
Computational Innovations in Cancer Research and How Computing is Transforming Drug Discovery and Development: A Review.

INTRODUCTION: Cancer is a major global health concern, causing millions of deaths each year due to the uncontrolled growth and spread of abnormal cell...

Mar 13 2026 41832735
Humans with function-disrupting variants in the myostatin gene (MSTN) have increased skeletal muscle mass and strength, and less adiposity.

Myostatin negatively regulates skeletal muscle size in multiple species, and therefore, myostatin blockade has been therapeutically explored to promot...

Mar 13 2026 41826329
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