Nephrology

Latest AI and machine learning research in nephrology for healthcare professionals.

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Automated detection of neonatal pulmonary hypertension in echocardiograms with a deep learning model.

BACKGROUND: In infants, pulmonary hypertension (PH) increases morbidity and mortality. Echocardiography, though standard, is time- and expertise-demanding. We propose a deep learning approach for automated PH detection using standard echocardiography videos, validated by the systolic eccentricity index (EIs). METHODS: The training and validation set comprised 975 videos and the held-out set 378 vi...

Sep 24 2025 40993360

Development of an interpretable machine learning model to predict short-term bleeding risk in patients receiving dual antithrombotic therapy following cardiac surgery.

INTRODUCTION: Bleeding is a serious complication in cardiac surgery, especially among patients receiving combined anticoagulant and antiplatelet therapy. Current prediction models rarely include those undergoing both valve surgery and coronary artery bypass grafting (CABG) or account for postoperative factors and dual antithrombotic therapy, limiting their clinical utility. AIM: This study aimed t...

Sep 24 2025 40991170
Detection and classification of medical images using deep learning for chronic kidney disease.

Chronic kidney disease (CKD) is an advancing disease which significantly impacts global healthcare, requiring early detection and prompt treatment is ...

Sep 24 2025 40991191
Imaging in chronic thromboembolic pulmonary hypertension: review of the current literature.

Chronic thromboembolic pulmonary hypertension (CTEPH) is a severe, life-threatening complication of pulmonary embolism with pulmonary hypertension (PH...

Sep 23 2025 40985291
In Silico Characterization of Bromo-DragonFLY Binding to the 5-HT2A Receptor: Molecular Insights Into a Potent Designer Psychedelic.

Bromo-DragonFLY (BDF), a potent designer psychedelic drug with hallucinogenic properties, has recently emerged as a significant recreational substance...

Sep 17 2025 40959960
AI-powered insights in pediatric nephrology: current applications and future opportunities.

Artificial intelligence (AI) is rapidly emerging as a transformative force in pediatric nephrology, enabling improvements in diagnostic accuracy, ther...

Sep 16 2025 40957986
Comparison of ChatGPT-3.5, ChatGPT-4.0 and DeepSeek in generating dietary plans for patients with chronic kidney disease: A focus on nutritional accuracy and dietary inflammation.

BACKGROUND: Our previous research indicated that ChatGPT-3.5 was inadequate in generating nutritionally accurate dietary plans for patients with chron...

Sep 14 2025 41135437
Elucidating anti-triple-negative breast cancer mechanisms and mitigating toxicity of Fritillaria thunbergii Miq.: A multi-omics and network pharmacology approach.

ETHNOPHARMACOLOGICAL RELEVANCE: Fritillaria thunbergii Miq. (Zhebeimu, ZBM) is traditionally recognized in Chinese medicine for its effects of clearin...

Sep 13 2025 40953776
Student Perceptions of a Custom Artificial Intelligence Clinical Case Companion.

INTRODUCTION: Artificial intelligence tools show promise in supplementing traditional physician assistant education, particularly in developing clinic...

Sep 10 2025 40928352
Identifying meaningful drug response biomarkers from public pharmacogenomic datasets with biologically informed interpretable neural networks.

With the advancements of next-generation sequencing, publicly available pharmacogenomic datasets from cancer cell lines provide a handle for developin...

Sep 2 2025 40914994
Optimizing guideline-directed medical therapy in chronic kidney disease and type 2 diabetes mellitus patients in primary care.

BACKGROUND: Despite KDIGO (Kidney Disease: Improving Global Outcomes) recommendations for renin-angiotensin-aldosterone system inhibitors (RAASi's) an...

Sep 1 2025 40902917
Central venous catheters tip positioning: Insights from a retrospective analysis.

BACKGROUND: Tunneled central venous catheters (tCVCs) are essential in hemodialysis when arteriovenous access is not feasible. Their correct positioni...

Aug 29 2025 40878638
Deep learning-based quantitative assessment of renal chronicity indices in lupus nephritis.

Renal chronicity indices (CI) have been identified as strong predictors of long-term outcomes in lupus nephritis (LN) patients. However, assessment by...

Aug 19 2025 40876259
Determining the Survival Impact and Cost-Effectiveness of Multi-Gene Panel Sequencing in Metastatic Colorectal Cancer With Super Learning Approaches.

OBJECTIVE: To determine the effectiveness and cost-effectiveness of multi-gene panel sequencing compared to single-gene KRAS testing for metastatic co...

Aug 13 2025 40802545
Tissue perfusion pressure: A novel hemodynamic measure to assess risk of acute kidney injury after cardiac surgery.

BACKGROUND: Optimal hemodynamic targets for preventing acute kidney injury (AKI) have remained elusive. We hypothesized that lower tissue perfusion pr...

Jul 16 2025 40680825
Solvent Replacement-Driven Ionic Liquid Thermoelectric Gel for Self-Powered Morse Code Communication Assisted by Machine Learning.

The development of ionic liquid gels (IL gels) with both high thermoelectric performance and mechanical flexibility is essential for advancing low-gra...

Jul 13 2025 40652523
Predictors of frontline doublet or triplet regimen initiation in transplant-ineligible newly diagnosed multiple myeloma.

AIMS: To identify predictors for initiation of frontline doublet versus triplet therapy for transplant-ineligible newly diagnosed multiple myeloma.

Jul 12 2025 40650954
Machine learning-based prediction of stone-free rate after retrograde intrarenal surgery for lower pole renal stones.

BACKGROUND: Lower pole renal stones (LPS) present unique challenges for retrograde intrarenal surgery (RIRS) due to unfavorable anatomical features, o...

Jul 12 2025 40650786
Prediction of gastrointestinal hemorrhage in cardiology inpatients using an interpretable XGBoost model.

Gastrointestinal bleeding (GIB) occurs more frequently in cardiovascular patients than in the general population, significantly affecting morbidity an...

Jul 12 2025 40652010
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