Neurology

Latest AI and machine learning research in neurology for healthcare professionals.

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An attention-augmented multimodal classification of alzheimer's disease and parkinson's disease vs healthy controls using MRI, EEG, and SNP data.

Due to the late manifestation of structural symptoms and symptomatic overlap, neurodegenerative diseases such as Parkinson's Disease (PD) and Alzheimer's Disease (AD) remain difficult to diagnose accurately. In order to categorize AD and PD in comparison to Healthy Controls (HC), this study suggests a multimodal classification framework that combines genetic Single Nucleotide Polymorphism (SNP) da...

Jan 16 2026 41545552

Sex Differences in Alzheimer's Disease: A Systematic Review of Two Decades of Neuroimaging Research.

OBJECTIVES: Given the heterogeneous nature of Alzheimer's Disease (AD) and its higher prevalence in females, it is crucial to understand sex-related differences in AD presentation and changes in the brain. METHODS: : This systematic review investigates sex differences in AD and summarizes key findings from neuroimaging studies over the past two decades to examine how genetics, hormones, and lifest...

Jan 16 2026 41546373
Hundred-Nanosecond Equivalent Pixel Dwell Time for Deep-Tissue 3D Three-Photon Fluorescence Microscopy via Sparse X-Y-Z Reconstruction.

Three-photon fluorescence microscopy (3PFM) enables high-resolution volumetric imaging in deep tissues but is fundamentally constrained by a trade-off...

Jan 16 2026 41546413
Enhancing Brain-Computer interface performance through source-level attention mechanism: An EEG motor imagery study.

BACKGROUND: Brain-computer interfaces (BCIs) enable direct communication between humans and machines by translating brain signals into control command...

Jan 16 2026 41548584
AggrescanAI: Prediction of Aggregation-Prone Regions Using Contextualized Embeddings.

Protein aggregation plays a central role in the pathogenesis of many neurodegenerative diseases and poses major challenges in protein engineering. A k...

Jan 16 2026 41548690
Alzheimer's disease prediction via an explainable CNN using genetic algorithm and SHAP values.

Convolutional neural networks (CNNs) are widely recognized for their high precision in image classification. Nevertheless, the lack of transparency in...

Jan 16 2026 41544026
Biometric Data in Post-Traumatic Stress Disorder Detection: A Scoping Review of Digital Health Applications.

CONTEXT: Post-traumatic stress disorder (PTSD) is mainly assessed through self-reports and clinician interviews, which can delay recognition and limit...

Jan 15 2026 41633287
Shape matters: Predicting Huntington's disease using progression modelling.

BACKGROUND: Despite evidence of group-level differences in striatal morphometry among persons with Huntington's Disease (PwHD), current models of HD p...

Jan 15 2026 41564629
ACFSENet: an adaptive cross-frequency global sparse encoding network for end-to-end EEG emotion recognition.

End-to-end EEG-based emotion recognition is attracting increasing attention due to its potential in human-computer interaction, mental health, and aff...

Jan 15 2026 41494206
Explainable AI for pain perception: subject-independent EEG decoding using DeepSHAP and CNNs.

Objective.Accurate classification of pain levels is essential for clinical monitoring, particularly in clinical populations with limited verbal commun...

Jan 15 2026 41499809
Accelerated brain aging in amyotrophic lateral sclerosis and its prognostic associations: a cohort study.

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, appearing to be associated with accelerated brain aging. Althoug...

Jan 15 2026 41535829
Stratifying amyloid burden in early Alzheimer's disease using cascaded attention-guided vision transformer using [¹⁸F]Florbetapir PET.

OBJECTIVES: This study aims to develop a deep learning model to assist physicians in accurately classifying negative, equivocal, and positive β-amyloi...

Jan 15 2026 41537783
Utilisation of Machine Learning Approaches Improves RNA-Seq Transcriptome Analyses in Alzheimer's Disease Brain.

UNLABELLED: Alzheimer’s disease (AD) is a neurodegenerative disorder that progressively deteriorates a person’s memory, as well as their ability to th...

Jan 15 2026 41537925
Automatic radiation-free evaluation of Cobb angle for spinal curvature based on fringe projection profilometry and deep learning technology.

OBJECTIVE: Pediatric scoliosis is the most prevalent spinal disorder, often leading to abnormal curvature and deformation of the spine. Early detectio...

Jan 15 2026 41537944
Prompting and Fine-Tuning Large Language Models for Parkinson Disease Diagnosis: Comparative Evaluation Study Using the PPMI Structured Dataset.

BACKGROUND: Parkinson disease (PD) presents diagnostic challenges due to its heterogeneous motor and nonmotor manifestations. Traditional machine lear...

Jan 15 2026 41539675
Modeling Ischemic Stroke Pathological Dynamics via Continuous Fields and Vector Flow.

Precise localization of perfusion deficits in diffusion-weighted MRI (DWI) is critical for acute ischemic stroke management. However, existing deep le...

Jan 15 2026 41540225
Smart patches for healthcare industry: a review of emerging technologies, challenges, and developmental opportunities.

BACKGROUND: Smart patch healthcare devices are emerging as a distinct user interface in decoding the bidirectional interaction of the five sense organ...

Jan 15 2026 41540378
Co-occurrence patterns and related risk factors of dementia and Parkinson's disease among older adults across 204 countries and territories: a spatial correspondence and systematic analysis.

BACKGROUND: Dementia and Parkinson's disease (PD) are among the most prevalent neurological disorders globally. Most previous research has focused on ...

Jan 15 2026 41540403
Investigating the molecular mechanisms of glutamine metabolism and mitochondria-related biomarkers in Alzheimer's disease through transcriptomics and experimental validation.

BACKGROUND: Alzheimer's disease (AD) is a prevalent neurodegenerative disorder. This study aims to identify biomarkers associated with glutamine metab...

Jan 15 2026 41540481
Robust multimodal mental workload classification: A cross-physiological condition machine learning approach.

BACKGROUND AND OBJECTIVE: Aircraft pilots can be faced with a high mental workload (MW) combined with moderate hypoxia and sleep restriction. We aimed...

Jan 14 2026 41576780
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