Neurology

From Diagnosis to Treatment: A Comprehensive Review of Biomarkers and Therapeutic Advances in Parkinson's Disease.

BACKGROUND: Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons, resulting in motor symptoms. Ongoing research shows promise for long-term solutions.

Identification of Potential Neddylation-related Key Genes in Ischemic Stroke based on Machine Learning Methods.

Ischemic stroke (IS) is a complex neurological disease that can lead to severe disability or even death. Understanding the molecular mechanisms involved in the occurrence and progression of IS is of great significance for developing effective treatment strategies. In this context, the role of neddylation refers to the potential impact of neddylation on various cellular processes, which may contrib...

Algorithmic Fairness of Machine Learning Models for Alzheimer Disease Progression.

IMPORTANCE: Predictive models using machine learning techniques have potential to improve early detection and management of Alzheimer disease (AD). Ho...

Bridging Neuroscience and Robotics: Spiking Neural Networks in Action.

Robots are becoming increasingly sophisticated in the execution of complex tasks. However, an area that requires development is the ability to act in ...

Early MS Identification Using Non-linear Functional Connectivity and Graph-theoretic Measures of Cognitive Task-fMRI Data.

INTRODUCTION: Functional neuroimaging has developed a fundamental ground for understanding the physical basis of the brain. Recent studies have extrac...

Effectiveness of Nicotinamide Phosphoribosyltransferase/Pre-B Cell Colony-enhancing Factor/Visfatin in preventing High Glucose-induced Neurotoxicity in an In-vitro Model of Diabetic Neuropathy.

INTRODUCTION: Diabetic neuropathy is a well-known complication of diabetes. Recently, hyperglycemia-induced toxicity has been confirmed to participate...

Menthol Dissolved in Dimethyl Sulfoxide Protects Against Epileptiform Activity Induced by Pentylenetetrazol in Male Rats.

INTRODUCTION: This research aims to investigate the protective action of menthol dissolved in dimethyl sulfoxide (DMSO) on experimental epileptiform a...

Reducing Gadolinium Contrast With Artificial Intelligence.

Gadolinium contrast is an important agent in magnetic resonance imaging (MRI), particularly in neuroimaging where it can help identify blood-brain bar...

Baseline factors and surgical procedures affecting changes in lower urinary tract symptoms after robot-assisted radical prostatectomy: the impact of nerve-sparing.

PURPOSE: To determine baseline factors and surgical procedures associated with clinically meaningful improvement or deterioration of lower urinary tra...

Outcomes of salvage robot-assisted radical prostatectomy in patients who had primary focal versus whole-gland ablation: a multicentric study.

In the present study, we present comparative outcomes of radical prostatectomy after whole-gland therapy (wg-SRARP) and focal gland therapy (f-SRARP)....

Risk assessment of inferior alveolar nerve injury after wisdom tooth removal using 3D AI-driven models: A within-patient study.

OBJECTIVE: To compare a three-dimensional (3D) artificial intelligence (AI)- driven model with panoramic radiography (PANO) and cone-beam computed tom...

Deep learning prediction of steep and flat corneal curvature using fundus photography in post-COVID telemedicine era.

Recently, fundus photography (FP) is being increasingly used. Corneal curvature is an essential factor in refractive errors and is associated with sev...

Multi-Level Ethical Considerations of Artificial Intelligence Health Monitoring for People Living with Parkinson's Disease.

Artificial intelligence (AI) has garnered tremendous attention in health care, and many hope that AI can enhance our health system's ability to care f...

A White-Box Testing for Deep Neural Networks Based on Neuron Coverage.

With the introduction of neuron coverage as a testing criterion for deep neural networks (DNNs), covering more neurons to detect more internal logic o...

A Flexible Wearable Supernumerary Robotic Limb for Chronic Stroke Patients.

In this study, we present a flexible wearable supernumerary robotic limb that helps chronic stroke patients with finger rehabilitation and grasping mo...

Analysis of intracranial pressure pulse waveform in studies on cerebrospinal compliance: a narrative review.

Continuous monitoring of mean intracranial pressure (ICP) has been an essential part of neurocritical care for more than half a century. Cerebrospinal...

A Perifacial EMG Acquisition System for Facial-Muscle-Movement Recognition.

This paper proposes a portable wireless transmission system for the multi-channel acquisition of surface electromyography (EMG) signals. Because EMG s...

Effectiveness of Robotics in Stroke Rehabilitation to Accelerate Upper Extremity Function: Systematic Review.

OBJECTIVE: To examine the effectiveness of robot-assisted therapy (RAT) combined with conventional therapy (CT) compared to CT alone in accelerating u...

Active compounds from flowers act via PI3K and ERK signaling pathways to offer neuroprotective effects against Parkinson's disease.

flowers, associated with diverse biological effects, could be utilized as functional food ingredients to play a crucial role in human health. In this...

Variability between human experts and artificial intelligence in identification of anatomical structures by ultrasound in regional anaesthesia: a framework for evaluation of assistive artificial intelligence.

BACKGROUND: ScanNavAnatomy Peripheral Nerve Block (ScanNav™) is an artificial intelligence (AI)-based device that produces a colour overlay on real-ti...