Neurology

Latest AI and machine learning research in neurology for healthcare professionals.

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Development of a spatial radiomics nomogram for predicting unfavorable outcomes after acute ischemic stroke: A multicenter study.

OBJECTIVE: To develop and externally validate a spatial radiomics nomogram integrating infarct location, lesion radiomics, and clinical predictors for individualized prediction of 90-day unfavorable outcomes in patients with acute ischemic stroke (AIS). MATERIALS AND METHODS: This multicenter retrospective study included 3,502 patients in the training cohort and 421 in the external validation coho...

Jul 9 2026 42435575

Machine learning-based prediction of 3-6-month post-stroke cognitive impairment using acute-phase clinical data: a two-center retrospective prognostic modeling study.

BACKGROUND: Post-stroke cognitive impairment (PSCI) is common and disabling, but identifying patients at risk early remains difficult. We developed and externally validated a retrospective machine-learning prognostic model using acute-phase predictors collected within 1 week after stroke onset to estimate PSCI risk assessed at 3-6 months after stroke. METHODS: Two inpatient rehabilitation cohorts ...

Jul 9 2026 42426822
Prediction of spinal cord injury after thoracoabdominal aortic repair by machine learning method.

BACKGROUND: Spinal cord injury (SCI) is a severe complication after thoracoabdominal aortic repair (TAAR), substantially increasing postoperative mort...

Jul 9 2026 42426824
Integrated multi-omics analysis identifies key microglial subpopulations and therapeutic targets in Parkinson's disease.

BACKGROUND: Parkinson's disease (PD) is a rapidly growing global health concern, with aging populations driving increasing prevalence. While neuronal ...

Jul 9 2026 42430983
Spectroscopic discrimination of bacterial species of variable pathogenicity through explainable machine learning.

Rapid and accurate identification of bacterial pathogens and their degree of pathogenicity is essential for guiding antimicrobial therapy. Current cul...

Jul 9 2026 42422903
A medium-density EMG system for real-time proportional and simultaneous neuroprosthetic hand control using lightweight neural networks.

OBJECTIVE: Restoring intuitive and natural hand control remains a key challenge in neuroprosthetics. A promising approach is to decode continuous fing...

Jul 9 2026 42423653
From Brain to Blood: Point-of-Care Detection of Biomarkers in Neurological Diseases.

Neurological diseases (NDs) continue to be a leading cause of disability and mortality worldwide, largely due to delayed diagnosis and limited access ...

Jul 9 2026 42424160
RMAF: A Deep Learning-Based Framework for Automatic Assessment of Spinal Cord Injured Rats Locomotor Performance Using the Horizontal Ladder Test.

Spinal cord injury (SCI) is a severe neurological disorder with high disability rates and limited treatment options. Its global incidence continues to...

Jul 9 2026 42425175
Prefrontal Connectivity Alterations and Oscillatory Dynamics in Cannabis Use Disorder.

Long-term cannabis use can result in the development of cannabis use disorder (CUD) and dependence via the endocannabinoid system pathway. A brain net...

Jul 9 2026 42425297
Baseline metabolic signature predicts cognitive improvement and longitudinal glycerophospholipid shifts track recovery in first-episode drug-naïve schizophrenia.

BACKGROUND: Cognitive impairment is a core yet treatment-resistant feature of schizophrenia (SZ), and reliable biomarkers predicting cognitive improve...

Jul 9 2026 42425477
Machine Learning to Identify Bacteremia and Meningitis in Febrile Infants: A Systematic Review.

CONTEXT: The accurate identification of febrile infants who are at risk for invasive bacterial infections (IBIs), ie, bacteremia and meningitis, is es...

Jul 9 2026 42419745
Machine-Learning-Based Prediction of Clinical Outcomes in Gliomas Using Glycomic Features.

Background: Gliomas are primary malignant brain tumors. Among them, grade IV astrocytomas represent the most aggressive form with limited treatment op...

Jul 9 2026 42428521
A predictive model for early neurological deterioration in medullary infarction based on explainable machine learning.

BACKGROUND: Medullary infarction is a severe subtype of ischemic stroke. Early neurological deterioration (END) is a common adverse event that can sig...

Jul 8 2026 42415422
Clinical Triage of Individuals With Warning Symptoms of Imminent Cardiac Arrest.

BACKGROUND: At least 50% of individuals who suffer sudden cardiac arrest (SCA) have warning symptoms before their SCA, but these are not sufficient to...

Jul 8 2026 42417030
Forecasting Excessive Anesthesia Depth Using EEG α-Spindle Dynamics and Machine Learning.

Accurately predicting transitions to anesthetic drugs overdosage is a critical challenge in general anesthesia as it requires the identification of EE...

Jul 8 2026 42418377
Validation of EEG mental workload markers using integrated statistical and machine learning analyses.

AIM: Attentional and working-memory processes can be monitored noninvasively using electroencephalography (EEG), which provides physiological indices ...

Jul 8 2026 42418665
Dietary patterns and Alzheimer's disease: East-west perspectives and future intervention strategies.

Among various modifiable risk factors, dietary patterns (DPs), as a holistic lifestyle intervention, have become a focus of current research due to th...

Jul 8 2026 42419161
xHD-Vox, an Automated Speech Model for Estimating Motor and Cognitive Scores in Huntington Disease: Development and Longitudinal Validation.

BACKGROUND: Huntington disease (HD) is a rare genetic neurodegenerative disease that causes progressive motor, cognitive, and psychiatric symptoms ove...

Jul 8 2026 42422859
Neurological roots of emotional ambivalence: from brain networks to clinical implications.

Introduction: Emotional ambivalence - the coexistence of conflicting positive and negative feelings toward the same object, event, or person - has bee...

Jul 7 2026 42411784
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