Neurology

Care Status of the ALS Patients With Long-Term Use of Tracheostomy Tube.

OBJECTIVE: To evaluate the care status of the amyotrophic lateral sclerosis (ALS) patients with long-term use of tracheostomy tube by caregivers of ALS patients.

Optimization of Gentisides Extraction from Gentiana rigescens Franch. ex Hemsl. by Response Surface Methodology.

Gentisides are a class of chemical compounds which is considered as potential therapeutic substance for treatment of neurodegenerative disorders. The heat reflux extraction conditions were optimized for seven kinds of gentisides from the root and rhizome of Gentiana rigescens Franch. ex Hemsl. by employing response surface method. Based on univariate test, a Box-Behnken design (BBD) was applied to...

Multiclass Posterior Probability Twin SVM for Motor Imagery EEG Classification.

Motor imagery electroencephalography is widely used in the brain-computer interface systems. Due to inherent characteristics of electroencephalography...

Protective Effects of Streblus asper Leaf Extract on H2O2-Induced ROS in SK-N-SH Cells and MPTP-Induced Parkinson's Disease-Like Symptoms in C57BL/6 Mouse.

This study investigated the effects of Streblus asper leaf extract (SA) on reactive oxygen species (ROS) in SK-N-SH cell culture and on motor function...

Postural visual dependence in asymptomatic type 2 diabetic patients without peripheral neuropathy during a postural challenging task.

UNLABELLED: Increasing evidence indicates that diabetes may negatively affect vestibular function, and postural control more so under postural challen...

A Clinically Relevant Method of Analyzing Continuous Change in Robotic Upper Extremity Chronic Stroke Rehabilitation.

BACKGROUND: Robots designed for rehabilitation of the upper extremity after stroke facilitate high rates of repetition during practice of movements an...

Vocal Fold Augmentation with Beta Glucan Hydrogel Cross-Linked by γ Irradiation for Enhanced Duration of Effect: In Vivo Animal Study.

This study explored a novel strategy to restore the vocal gap by using cross-linked β-glucan hydrogel by γ-irradiation. An aqueous solution of 5 wt% β...

Classification of first-episode psychosis in a large cohort of patients using support vector machine and multiple kernel learning techniques.

First episode psychosis (FEP) patients are of particular interest for neuroimaging investigations because of the absence of confounding effects due to...

"Look at my classifier's result": Disentangling unresponsive from (minimally) conscious patients.

Given the fact that clinical bedside examinations can have a high rate of misdiagnosis, machine learning techniques based on neuroimaging and electrop...

Decoding intracranial EEG data with multiple kernel learning method.

BACKGROUND: Machine learning models have been successfully applied to neuroimaging data to make predictions about behavioral and cognitive states of i...

Use of artificial neural networks to predict the probability of developing new cerebral metastases after radiosurgery alone.

BACKGROUND: The present study aimed to predict the probability of developing new cerebral metastases after Gamma Knife radiosurgery (GKR) alone in pat...

Improved system identification using artificial neural networks and analysis of individual differences in responses of an identified neuron.

Mathematical modelling is used routinely to understand the coding properties and dynamics of responses of neurons and neural networks. Here we analyse...

Predicting healthy older adult's brain age based on structural connectivity networks using artificial neural networks.

Brain ageing is followed by changes of the connectivity of white matter (WM) and changes of the grey matter (GM) concentration. Neurodegenerative dise...

Relative Bioavailability of a Single Dose of Belimumab Administered Subcutaneously by Prefilled Syringe or Autoinjector in Healthy Subjects.

Intravenous belimumab is approved for the treatment of systemic lupus erythematosus; subcutaneous self-administration would enable greater patient acc...

Fractionated stereotactic radiation therapy for vestibular schwannomas: Dosimetric factors predictive of hearing outcomes.

PURPOSE: To determine dosimetric factors predictive of hearing loss in vestibular schwannoma (VS) patients treated with definitive fractionated stereo...

Cognitively impaired elderly exhibit insulin resistance and no memory improvement with infused insulin.

Insulin resistance is a risk factor for Alzheimer's disease (AD), although its role in AD etiology is unclear. We assessed insulin resistance using fa...

Liquid chromatography-tandem mass spectrometry method for simultaneous determination of valproic acid and its ene-metabolites in epilepsy patient plasma.

A simple and high throughput method was developed and validated for simultaneous determination of valproic acid and its two toxicant ene-metabolites, ...

Robot training for hand motor recovery in subacute stroke patients: A randomized controlled trial.

BACKGROUND: Evidence of superiority of robot training for the hand over classical therapies in stroke patients remains controversial. During the subac...

Robot-based assessment of motor and proprioceptive function identifies biomarkers for prediction of functional independence measures.

BACKGROUND: Neurological impairments following stroke impact the ability of individuals to perform daily activities, although the relative impact of i...

A Spiking Neural Network Methodology and System for Learning and Comparative Analysis of EEG Data From Healthy Versus Addiction Treated Versus Addiction Not Treated Subjects.

UNLABELLED: This paper introduces a method utilizing spiking neural networks (SNN) for learning, classification, and comparative analysis of brain dat...