Neurology

Latest AI and machine learning research in neurology for healthcare professionals.

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RepSPD: Enhancing SPD Manifold Representation in EEGs via Dynamic Graphs

Decoding brain activity from electroencephalography (EEG) is crucial for neuroscience and clinical applications. Among recent advances in deep learning for EEG, geometric learning stands out as its theoretical underpinnings on symmetric positive definite (SPD) allows revealing structural connectivity analysis in a physics-grounded manner. However, current SPD-based methods focus predominantly on s...

Feb 26 2026 2602.22981v1

Optimizing Neural Network Architecture for Medical Image Segmentation Using Monte Carlo Tree Search

This paper proposes a novel medical image segmentation framework, MNAS-Unet, which combines Monte Carlo Tree Search (MCTS) and Neural Architecture Search (NAS). MNAS-Unet dynamically explores promising network architectures through MCTS, significantly enhancing the efficiency and accuracy of architecture search. It also optimizes the DownSC and UpSC unit structures, enabling fast and precise model...

Feb 25 2026 2602.22361v1
Spontaneous emergence of topographic organization in a multistream convolutional neural network

Neurons in the cerebral cortex are organized topographically. In the primate visual cortex, neighboring neurons often respond to similar stimulus para...

Disease Progression and Subtype Modeling for Combined Discrete and Continuous Input Data

Disease progression modeling provides a robust framework to identify long-term disease trajectories from short-term biomarker data. It is a valuable t...

Feb 25 2026 2602.22018v1
RelA-Diffusion: Relativistic Adversarial Diffusion for Multi-Tracer PET Synthesis from Multi-Sequence MRI

Multi-tracer positron emission tomography (PET) provides critical insights into diverse neuropathological processes such as tau accumulation, neuroinf...

Feb 24 2026 2602.21345v1
Restoring brain-to-text communication in a person with dysarthria from pontine stroke using an intracortical brain-computer interface

Restoring communication for people with dysarthria secondary to pontine stroke remains a critical challenge. Intracortical brain-computer interfaces (...

Hierarchic-EEG2Text: Assessing EEG-To-Text Decoding across Hierarchical Abstraction Levels

An electroencephalogram (EEG) records the spatially averaged electrical activity of neurons in the brain, measured from the human scalp. Prior studies...

Feb 24 2026 2602.20932v1
Making Conformal Predictors Robust in Healthcare Settings: a Case Study on EEG Classification

Quantifying uncertainty in clinical predictions is critical for high-stakes diagnosis tasks. Conformal prediction offers a principled approach by prov...

Feb 23 2026 2602.19483v1
PaReGTA: An LLM-based EHR Data Encoding Approach to Capture Temporal Information

Temporal information in structured electronic health records (EHRs) is often lost in sparse one-hot or count-based representations, while sequence mod...

Feb 23 2026 2602.19661v1
EMAD: Evidence-Centric Grounded Multimodal Diagnosis for Alzheimer's Disease

Deep learning models for medical image analysis often act as black boxes, seldom aligning with clinical guidelines or explicitly linking decisions to ...

Feb 22 2026 2602.19178v1
Automated epilepsy and seizure type phenotyping with pre-trained language models

Background Epilepsy is a common neurologic disorder characterized by recurrent, unprovoked seizures. Epilepsy manifests as different seizure types and...

Prompting is All You Need: How to Make LLMs More Helpful for Clinical Decision Support

Importance: Large language models (LLMs) offer potential decision support, but their accuracy varies. Prompt engineering can generally enhance LLM beh...

AI-Detected Asymptomatic Atrial Fibrillation and Risk of Incident Ischemic Stroke and Cardiovascular Events: A UK Biobank Study

Background: Advances in wearable devices and machine-learning-based ECG analysis enable highly accurate detection of atrial fibrillation (AF) outside ...

Development and Characterization of Self-Tracing Neural Progenitor Cells for Mapping Their Synaptic Integration into Endogenous Neural Networks

Neural progenitor cell (NPC) transplantation holds immense promise for neurodegenerative and traumatic central nervous system (CNS) pathologies. Howev...

LERD: Latent Event-Relational Dynamics for Neurodegenerative Classification

Alzheimer's disease (AD) alters brain electrophysiology and disrupts multichannel EEG dynamics, making accurate and clinically useful EEG-based diagno...

Feb 20 2026 2602.18195v1
Generative Model via Quantile Assignment

Deep Generative models (DGMs) play two key roles in modern machine learning: (i) producing new information (e.g., image synthesis) and (ii) reducing d...

Feb 20 2026 2602.18216v1
Balanced deep learning on multi-omics networks identifies molecular subgroups of pathological brain aging

Abstract Background Neurodegenerative diseases, including Alzheimer's disease (AD), exhibit substantial clinical and molecular heterogeneity, complica...

Pan-cell-type prediction of splicing patterns from sequence and splicing factor expression

Alternative splicing is a core determinant of cell-type-specific gene expression in humans, and its dysregulation contributes to many diseases includi...

Structured Prototype-Guided Adaptation for EEG Foundation Models

Electroencephalography (EEG) foundation models (EFMs) have achieved strong performance under full fine-tuning but exhibit poor generalization when sub...

Feb 19 2026 2602.17251v1
Probability-Invariant Random Walk Learning on Gyral Folding-Based Cortical Similarity Networks for Alzheimer's and Lewy Body Dementia Diagnosis

Alzheimer's disease (AD) and Lewy body dementia (LBD) present overlapping clinical features yet require distinct diagnostic strategies. While neuroima...

Feb 19 2026 2602.17557v1
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