Neurology

Latest AI and machine learning research in neurology for healthcare professionals.

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Latent Space Topology Evolution in Multilayer Perceptrons

This paper introduces a topological framework for interpreting the internal representations of Multilayer Perceptrons (MLPs). We construct a simplicial tower, a sequence of simplicial complexes connected by simplicial maps, that captures how data topology evolves across network layers. Our approach enables bi-persistence analysis: layer persistence tracks topological features within each layer a...

EgoBrain: Synergizing Minds and Eyes For Human Action Understanding

The integration of brain-computer interfaces (BCIs), in particular electroencephalography (EEG), with artificial intelligence (AI) has shown tremendous promise in decoding human cognition and behavior from neural signals. In particular, the rise of multimodal AI models have brought new possibilities that have never been imagined before. Here, we present EgoBrain --the world's first large-scale, ...

Fast SSVEP Detection Using a Calibration-Free EEG Decoding Framework

Steady-State Visual Evoked Potential is a brain response to visual stimuli flickering at constant frequencies. It is commonly used in brain-computer...

Alzheimers Disease Classification in Functional MRI With 4D Joint Temporal-Spatial Kernels in Novel 4D CNN Model

Previous works in the literature apply 3D spatial-only models on 4D functional MRI data leading to possible sub-par feature extraction to be used fo...

Understanding and Mitigating Cross-lingual Privacy Leakage via Language-specific and Universal Privacy Neurons

Large Language Models (LLMs) trained on massive data capture rich information embedded in the training data. However, this also introduces the risk ...

Understanding and Mitigating Cross-lingual Privacy Leakage via Language-specific and Universal Privacy Neurons

Large Language Models (LLMs) trained on massive data capture rich information embedded in the training data. However, this also introduces the risk ...

Real-Time Precision Tracking System in Periprosthetic Acetabular Osteotomy With Osteotome Chisel Elastic Deformation Consideration.

The periprosthetic acetabular osteotomy (PAO) is a commonly used technique in orthopedics for treating developmental hip dysplasia and hip dislocation...

Jun 1 2025 40214620
Whole Brain 3D T1 Mapping in Multiple Sclerosis Using Standard Clinical Images Compared to MP2RAGE and MR Fingerprinting.

Quantitative T1 and T2 mapping is a useful tool to assess properties of healthy and diseased tissues. However, clinical diagnostic imaging remains dom...

Jun 1 2025 40235062
Modulation of insulin aggregation by betaine and proline directly observed via real-time super-resolution microscopy.

Protein aggregation is associated with a spectrum of neurodegenerative diseases. Although many small ligands have been found to modulate or inhibit pr...

Jun 1 2025 40371766
Prediction Model and Nomogram for Amyloid Positivity Using Clinical and MRI Features in Individuals With Subjective Cognitive Decline.

There is an urgent need for the precise prediction of cerebral amyloidosis using noninvasive and accessible indicators to facilitate the early diagnos...

Jun 1 2025 40439500
Differentiating Treatment-Resistant Depression With and Without Parkinsonism in the Elderly From a Psychiatric Perspective by Tc-TRODAT-1 SPECT Imaging.

OBJECTIVES: Late-life depression often overlaps with neurodegenerative diseases leading to diagnostic and treatment challenges for neuropsychiatrists....

Jun 1 2025 40445019
Early outcomes with virtual surgical planning software and patient-specific instrumentation in adult spinal deformity.

OBJECTIVE: Software engineering innovations have led to the development of virtual surgical planning software (VSPS) for deformity correction. VSPS us...

Jun 1 2025 40450877
EEG-ConvoBLSTM: A novel hybrid model for efficient EEG signal classification.

Electroencephalogram (EEG) signals pose a challenge to emotion recognition (ER) tasks due to their complexity and individual differences. Conventional...

Jun 1 2025 40454762
Neural Metabolic Networks: Key Elements of Healthy Brain Function.

Neural networks are responsible for processing sensory stimuli and driving the synaptic activity required for brain function and behavior. This comput...

Jun 1 2025 40454774
Targeted Muscle Reinnervation and Regenerative Peripheral Nerve Interface for Myoelectric Prosthesis Control: The State of Evidence.

Prosthetic rehabilitation after amputation poses significant challenges, often due to functional limitations, residual limb pain (RLP), and phantom li...

Jun 1 2025 40459463
Development of a Diagnostic Prediction Model for Post-Stroke Cognitive Impairment in Acute Large Vessel Occlusion Stroke Using Multimodal MRI and PET/CT: A Study Protocol.

OBJECTIVE: Stroke is a leading cause of morbidity and disability worldwide. Post-stroke cognitive impairment (PSCI) significantly affects long-term pr...

Jun 1 2025 40495418
Abnormal Static and Dynamic Functional Connectivity in Tension-Type Headache: A Support Vector Machine Analysis.

Tension-type headache (TTH) is a primary headache with the highest prevalence. Previous studies have revealed the local brain abnormalities of TTH pat...

Jun 1 2025 40519127
Revolution of AAV in Drug Discovery: From Delivery System to Clinical Application.

Adeno-associated virus (AAV) is a non-enveloped DNA virus infecting a wide variety of species, tissues, and cell types, which is recognized as a safe ...

Jun 1 2025 40536197
Chinese acupoint therapies in cancer pain management: research advances and future perspectives.

Cancer pain management (CPM) is crucial in oncology care, with current approaches including pharmacotherapy, radiotherapy, chemotherapy, nerve blocks,...

Jun 1 2025 40402471
Large-scale plasma proteomic profiling unveils diagnostic biomarkers and pathways for Alzheimer's disease.

Proteomic studies have been instrumental in identifying brain, cerebrospinal fluid and plasma proteins associated with Alzheimer's disease (AD). Here,...

Jun 1 2025 40394224
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