Neurology

Latest AI and machine learning research in neurology for healthcare professionals.

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Detection of multiple per- and polyfluoroalkyl substances (PFAS) using a biological brain-based gas sensor

Per- and polyfluoroalkyl substances (PFAS) are man-made compounds that bioaccumulate in environments. Current PFAS detection technologies encounter difficulty in detecting trace concentrations and require complex data processing, limiting their on-site applicability. By leveraging biological chemical sensing systems (insect olfaction) we can detect broad ranges of PFAS. Insects’ advanced combinato...

Toward Unified Biomarkers for Focal Epilepsy

Accurately localizing the epileptogenic network (EpiNet) remains a major barrier to effective epilepsy treatment, largely due to limited mechanistic understanding. The EpiNet is a patient-specific brain network shaped by complex, overlapping pathology. While combining biomarkers can improve localization, it also generates high-dimensional feature data that increases the risk of overfitting and red...

Lysosomal multi-omics reveals altered sphingolipid catabolism as driver of lysosomal dysfunction in the aging brain

Recent data indicate that lipid composition has profound influence on the brain function and that changes in lipid homeostasis affect brain aging and ...

CASTLE: a training-free foundation-model pipeline for cross-species behavioral classification

Accurately and efficiently quantifying animal behavior at scale without intensive manual labeling is a long-standing challenge for neuroscience and et...

A Novel 3D Visualization Method in Mice Identifies the Periportal Lamellar Complex (PLC) as a Key Regulator of Hepatic Ductal and Neuronal Branching Morphogenesis

The liver’s microenvironment consists of interconnected vascular, biliary, and neural networks that regulate homeostasis and disease progression. Howe...

Learning Residual-based Biomarkers of Cognitive Health via Self-Supervised Learning on EEG State Transitions

Deep learning (DL) models have achieved impressive performance in EEG-based prediction tasks, but they often lack interpretability, limiting their cli...

Octopamine signaling from clock neurons plays dual roles in Drosophila long-term memory

Circadian clock genes are best known for regulating circadian rhythms, but they also play crucial roles in memory processes. This suggests that memory...

Improved sensory representations as a result of temporal adaptation

Human perception is robust under challenging conditions, for example when sensory inputs change over time. Temporal adaptation in the form of reduced ...

Integrating Data Across Oscillatory Power Bands Predicts the Seizure Onset Zone in Focal Epilepsies

Accurate identification of the seizure onset zone (SOZ) using intracranial electroencephalography (iEEG) remains challenging. Although diverse methods...

Spatio Temporal Attentional EEGNet: An Enhanced Deep Learning Model for Cognitive Workload Detection

Deep learning has emerged as a powerful tool for extracting meaningful patterns from electroencephalography (EEG) signals, particularly for mental wor...

Deep Coupled Kuramoto Oscillatory Neural Network (DcKONN): A Biologically Inspired Deep Neural Model for EEG Signal Analysis

Deep neural networks applied to signal processing tasks often need specialized architectural mechanisms to capture the temporal history of input signa...

Designing a Model to Detect Beta Burst in EEG Using Nonlinear Dynamic Features Based on Machine Learning

Beta bursts are brief, transient increases in beta-band (13–30 Hz) EEG activity that play a key role in motor control, particularly in processes like ...

Ascending propriospinal modulation of thoracic sympathetic preganglionic neurons during lumbar locomotor activity

Although the autonomic sympathetic system is activated in parallel with locomotion, the underlying neural mechanisms mediating this coordination are n...

Hippocampal grey matter changes across scales in Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive and debilitating neurodegenerative disease of the central nervous system, characterized by deterioration in ...

Integrative Chemical Genetics Platform Identifies Condensate Modulators Linked to Neurological Disorders

Aberrant biomolecular condensates are implicated in multiple incurable neurological disorders, including Amyotrophic Lateral Sclerosis, Frontotemporal...

A Systematic Fairness Evaluation of Racial Bias in Alzheimer’s Disease Diagnosis Using Machine Learning Models

Alzheimer’s disease (AD) is a major global health concern, expected to affect 12.7 million Americans by 2050. Machine learning (ML) algorithms have be...

Cooperative multi-view integration with Scalable and Interpretable Model Explainer

Single-omics approaches often provide a limited perspective on complex biological systems, whereas multi-omics integration enables a more comprehensiv...

A Hybrid Knowledge- and Data-driven Model for Automatic Assessment of Chemically Induced Spiking Patterns in C-fiber Microneurography

Analyzing temporal spike patterns in nociceptors recorded via microneurography is challenging due to the use of a single recording electrode, waveform...

A groove brain-music interface for enhancing individual experience of urge to move

When we listen to music, we often feel a pleasurable urge to move to music, known as groove. While previous studies have identified musical features t...

A deep learning framework for understanding cochlear implants

Sensory prostheses replace dysfunctional sensory organs with electrical stimulation but currently fail to restore normal perception. Outcomes may be l...

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