Neurology

Latest AI and machine learning research in neurology for healthcare professionals.

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Characterizing Dementia Phenotypes from Unstructured EHR Notes with Generative AI and Interpretable Machine Learning

Dementia encompasses diverse clinical syndromes where diseases of the brain can manifest as impaired cognitive abilities, such as in Alzheimer’s disease (AD) and behavioral-variant frontotemporal dementia (bvFTD). The diversity of symptom presentations often results in challenges in diagnosis. Crucial clinical information remains in unstructured narrative notes within electronic health records (EH...

Sex adaptive deep recurrent neural networks for Parkinson’s disease detection using 5-second vertical ground reaction force signals

This study introduces an innovative sex-stratified methodology for the identification of Parkinson’s disease (PD) using vertical ground reaction force (VGRF) data obtained from foot sensors during ambulation. We devised and evaluated four distinct recurrent neural network designs. We identified a substantial deficiency in existing diagnostic methodologies that infrequently utilize sex-stratified t...

CSF Proteomics and Machine Learning Reveal Distinct Stages Across the Alzheimer’s Disease Continuum

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by heterogeneous pathophysiological changes that begin years before symptoms em...

Quantitative EEG-Based Deep Learning for Neonatal Seizure Detection using Conv-LSTM

Neonatal seizures cause significant morbidity and mortality, both acutely and in the long term, contributing to adverse neurodevelopmental outcomes. T...

Automatic detection of simulated artifacts on T1w magnetic resonance images: comparing performance of different QC strategies

The reliability of MRI-derived measures critically depends on image quality. Poor-quality scans can obscure anatomical detail and compromise the accur...

Examining public acceptance of AI versus human-centric dementia care across NHS England’s dementia pathway stages

With dementia diagnoses in the UK projected to exceed one million in 2025, there is an urgent need for scalable and effective care solutions to ease p...

Mind’s eye: Saccade-related evoked potentials support visual encoding in humans

In active vision, the brain receives and encodes discontinuous streams of visual information gated by saccadic eye movements. Saccadic modulation of n...

Bedtime Brain State Predicts the Impact of Closed-Loop Auditory Stimulation on Sleep and Cognition

Sleep interventions targeting slow-wave activity (SWA) show heterogeneous effects across individuals. We investigated whether pre-sleep brain states p...

Circulating Metabolites are Linked to Dementia and Brain Imaging Phenotypes, and Mediate Modifiable Risk Pathways

Dementia poses an escalating global health burden, yet its underlying mechanisms remain incompletely understood. In this large-scale, targeted metabol...

3DeepVOG: An Open-Source Framework for Real-Time, Accurate 3D Gaze Tracking with Deep Learning

Eye movements are key biomarkers for diagnosing and monitoring neuro-otological, neuro-ophthalmological and neurodegenerative disorders. Video-oculogr...

Sleep Staging Foundation Models Encode Neural Disorder-Related EEG Representations that Generalize to Wakefulness

To leverage sleep foundation models trained on large datasets of polysomnography for neurological disorder detection during an awake state. Three publ...

Research on Epilepsy Detection and Recognition Based on the Combination of Time Frequency Transform and Deep Learning Model

To improve the detection performance of epileptic electroencephalogram (EEG) signals and address their non-stationary characteristics, this paper comp...

Explainable machine learning on weighted connectivity networks across frequencies for outcome prediction in comatose patients

Accurate early prediction of neurological outcomes in comatose patients after cardiac arrest is critical for guiding therapeutic decisions and improvi...

Circulating microglia-derived extracellular vesicles predict recovery after rehabilitation in stroke survivors

Timely intensive rehabilitation is crucial to contrast the negative escalation of events that follow a stroke injury, to promote tissue regeneration, ...

Arachnoiditis: Leveraging crowdsourcing and AI in a cross-sectional study of 1,105 cases to improve identification, understanding, and treatment

Arachnoiditis, a painful and potentially disabling neurological condition, results from persistent inflammation of the spinal cord pia-arachnoid membr...

A Zero-Burden Sleep Foundation Model Built on Cardiorespiratory Signals from 800,000+ Hours of Multi-Ethnic Sleep Recordings

Sleep disorders pose a major global health burden and are associated with a wide range of adverse health outcomes. Polysomnography (PSG) is the gold s...

DeepFLAIR*: Improving Multiple Sclerosis Diagnostic Imaging Workflow Using Deep Learning

Magnetic resonance imaging (MRI) plays a central role in diagnosing multiple sclerosis (MS), yet conventional T2-FLAIR imaging provides limited specif...

Mobile Objective Diagnostics of Macular Degeneration using Dark-Adapted Visual Evoked Potentials

Delayed Dark-Adapted vision Recovery (DAR) is a known biomarker for Age-related Macular Degeneration (AMD); however, its measurement is often cumberso...

Sleep-Derived Features From Multi-Night In-ear EEG Identify Patterns Linked To Mild Cognitive Impairment

We investigated whether sleep features from multi-night, at-home in-ear EEG could distinguish mild cognitive impairment (MCI) from cognitively normal ...

Resting-state EEG and machine learning to investigate cortical connectivity as a biomarker in chronic mTBI

Mild traumatic brain injury (mTBI) is a heterogeneous condition with long-term sequelae, yet diagnosis in the chronic stage remains limited by relianc...

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