Neurology

Latest AI and machine learning research in neurology for healthcare professionals.

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Environmental Exposures and Neuroimaging in Children with Neurodevelopmental Disorders: A Scoping Review.

PURPOSE OF REVIEW: Neurodevelopmental disorders (NDDs) such as autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) have been linked to environmental exposures, yet the underlying neurobiological mechanisms remain poorly understood. Magnetic resonance imaging (MRI) offers an important in vivo tool for examining how environmental neurotoxicants impact brain development...

May 1 2026 42062691

Multimodal deep learning neuroimaging approach to enhance CT-based diagnosis of Alzheimer's disease.

Neuroimaging plays a critical role in the diagnosis of Alzheimer's disease (AD), with Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) providing detailed structural and functional information for deep learning (DL) based classification. However, their high cost and limited availability restrict widespread clinical use. Computed Tomography (CT), while affordable and widely ac...

Apr 30 2026 42085916
A NETs-centric multi-omics framework prioritizes PGLYRP1 and MMP9 as subtype-associated thromboinflammatory biomarker candidates and putative therapeutic hypotheses in ischemic stroke.

Neutrophil extracellular traps are implicated in immunothrombosis and neuroinflammation in ischemic stroke, but blood-based markers that distinguish s...

Apr 30 2026 42066918
Integrated plasma proteomics and metabolomics reveal immunometabolic pathways and predictive signatures for age-related eye diseases.

BACKGROUND AND AIMS: Age-related eye diseases (AREDs) share aging as a major risk factor, but the systemic molecular changes preceding disease onset r...

Apr 30 2026 42066985
Deep-learning Saturation Transfer Magnetic Resonance Fingerprinting (ST-MRF) in Patients with Parkinson's Disease.

Parkinson's disease (PD) is marked by progressive neurodegeneration in the substantia nigra (SN). This study evaluated deep-learning saturation-transf...

Apr 30 2026 42069025
Machine learning based multi-omics analysis reveals key molecular determinants of Parkinson's disease severity.

While single-omics analyses of Parkinson's Disease (PD) have demonstrated their ability in revealing the underlying molecular mechanisms, they often f...

Apr 30 2026 42069091
The applications of single-cell and spatial transcriptomics in neuroscience and brain disorders.

Spatial transcriptomics extends traditional transcriptomic methods by quantifying gene expression within intact tissues while preserving each cell's p...

Apr 30 2026 42069165
Microstate permutation complexity of EEG signals distinguishes minimally conscious state plus from minimally conscious state minus.

BACKGROUND: Accurately distinguishing minimally conscious state plus (MCS+) from minimally conscious state minus (MCS-) is critical for prognosis and ...

Apr 30 2026 42063046
Discovering non-linear dynamics of miRNAs in Alzheimer's disease-related cognitive impairment: a cross-species approach with explainable machine learning.

BACKGROUND: MicroRNA (miRNA) biomarker studies in Alzheimer's disease (AD) typically assume monotonic relationships between expression levels and dise...

Apr 30 2026 42063169
Interpretable Deep Survival Analysis of Alzheimer's Disease via Metabolic Genetic Variants.

BACKGROUND: Alzheimer's disease (AD) is a progressive neurodegenerative disease. Traditional models for estimating AD onset cannot capture nonlinear i...

Apr 30 2026 42063212
Machine learning-based prediction model for paresthesia improvement after open carpal tunnel release: a preliminary study.

BACKGROUND: Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy of the hand. While carpal tunnel release surgery generally provides ...

Apr 30 2026 42057064
A prospective multimethod investigation of cancer-related pain integrating clinical data and machine learning: results from the RUGGI Study.

BACKGROUND: Cancer-related pain is a multidimensional phenomenon, and key determinants of pain intensity remain unclear. The aim of this study was to ...

Apr 30 2026 42057124
Neural Stem Cell-Derived Extracellular Vesicles: The Next Frontier in Neurological and Neurodegenerative Diseases.

The present manuscript provides a comprehensive overview of neural stem cell (NSC)-derived extracellular vesicles (NSC-EVs( as a cell-free approach to...

Apr 30 2026 42060081
Subject-Independent Deep Learning Framework for Motor Imagery Electroencephalogram Decoding in Neurorehabilitation.

Motor imagery (MI) has emerged as a pivotal paradigm in non-invasive brain-computer interfaces (BCIs) for neurorehabilitation, enabling motor function...

Apr 30 2026 42060426
Benchmarking ERP Analysis: Manual Features, Deep Learning, and Foundation Models.

Event-related potential (ERP), a specialized paradigm of electroencephalographic (EEG), reflects neurological responses to external stimuli or events,...

Apr 30 2026 42060433
Magnetic Resonance Neurography: Evolution, Technical Foundations, and Future Directions.

ABSTRACT: In the past 20 years, magnetic resonance neurography has evolved from an experimental technique into an essential diagnostic pillar for peri...

Apr 30 2026 42061306
Deep Learning-Based Identification of Surgical Candidacy for Cervical Spinal Cord Decompression.

BACKGROUND: Artificial intelligence has previously demonstrated the capability to interpret cervical spine imaging. The present study aims to identify...

Apr 30 2026 42061991
Complexity of resting cortical activity predicts neurophysiological responses to theta-burst stimulation but fails to generalize: A rigorous machine-learning approach.

BACKGROUND: Substantial variability in individual responses to intermittent theta-burst stimulation (iTBS) limits its clinical efficacy, yet neurophys...

Apr 30 2026 42060616
Interpretable multivariate survival models: Improving predictions for conversion from mild cognitive impairment to Alzheimer's disease via data fusion and machine learning.

Accurately predicting which individuals with mild cognitive impairment (MCI) will progress to Alzheimer's disease (AD) can improve patient care. This ...

Apr 30 2026 42060649
Machine learning to diagnose, classify and predict phenoconversion in isolated REM sleep behavior disorder.

Rapid eye movement (REM) sleep behaviour disorder (RBD), particularly its idiopathic/isolated form (iRBD), is a prodromal marker for α-synucleinopathi...

Apr 29 2026 42068794
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