Neurology

Latest AI and machine learning research in neurology for healthcare professionals.

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Assessing racial disparities in dementia-related vulnerabilities: a machine learning analysis of social, environmental, and climate factors.

INTRODUCTION: Racial differences in exposure to area-level social determinants of health (SDoH) may contribute to distinct vulnerability profiles among people living with dementia. METHODS: This cross-sectional study used data from the OCHIN Community Health Equity Database to examine SDoH factors among patients with dementia and mild cognitive impairment. SDoH measures encompassed social, environ...

Apr 8 2026 41952418

EXPRESS: Static and dynamic perspective on brain activity and functional connectivity alternations in the comorbidity of chronic pain and depression: An fMRI study in rats.

BACKGROUND: Clinically, chronic pain and depression often coexist in multiple diseases and reciprocally reinforce each other, which greatly escalates the difficulty of treatment. The alteration in neural networks underlying the chronic pain/depression comorbidity remains unclear. METHODS: Spared nerve injury (SNI) was performed to establish a rat model of comorbidity of chronic pain and depression...

Apr 8 2026 41948792
AI-Derived LA Volume Index, LA/RA and LA/LV Volume Ratios From Coronary Artery Calcium Scans Predict Long-Term Atrial Fibrillation and Stroke.

BACKGROUND: The AI-CVD initiative aims to extract actionable insights from coronary artery calcium (CAC) scans beyond the traditional CAC score. Altho...

Apr 8 2026 41948813
A multicenter, video-EEG-based validation of a multimodal wearable device for focal seizure detection in adults: The SeizeIT2 study.

OBJECTIVE: Currently available wearable devices for detecting focal seizures primarily target major motor seizures or involve semi-invasive subscalp i...

Apr 8 2026 41949013
Development and Multicenter External Validation of a Real-Time Artificial Intelligence Diagnostic System for Diabetic Peripheral Neuropathy Based on Wearable Devices.

Diabetic peripheral neuropathy (DPN) ranks among the most common complications of diabetes worldwide, often leading to severe morbidity if undetected ...

Apr 8 2026 41950120
FetalSleepNet: A Transfer Learning Framework with Spectral Equalisation Domain Adaptation for Fetal Sleep State Classification.

OBJECTIVE: Fetal sleep state classification is essential for identifying neurodevelopmental complications like hypoxia, but manual annotation is subje...

Apr 8 2026 41950122
Automated quantification of coronal balance in spinal deformity: a safety-aware clinical workflow.

The assessment of coronal balance is critical for cosmetic appearance and quality of life in patients with adolescent idiopathic scoliosis (AIS), yet ...

Apr 8 2026 41951866
Plasma proteomic signatures linking preserved ratio impaired spirometry to cardiometabolic diseases and multimorbidity: A longitudinal cohort study.

BACKGROUND: Preserved ratio impaired spirometry (PRISm), defined by reduced FEV1 with preserved FEV1/FVC ratio, has been linked to cardiometabolic dis...

Apr 7 2026 41944044
Diagnostic performance of AI-based EEG interpretation versus human clinical experts for epilepsy detection: systematic review and meta-analysis.

BACKGROUND: Electroencephalography (EEG) interpretation for epilepsy diagnosis faces persistent challenges including specialist shortages, variable in...

Apr 7 2026 41956141
Drug repurposing in Alzheimer's disease: Emerging therapeutic strategies and promising candidates.

Alzheimer's disease is a progressive neurodegenerative disorder, and the most common cause of dementia, which causes 60-70 % of cases worldwide, and i...

Apr 7 2026 41956136
Leveraging machine learning to predict Parkinson's disease using pre-symptomatic proteomics data.

In Parkinson's disease, non-motor symptoms precede the characteristic motor manifestations by up to 20 years. However, predicting the disease risk rem...

Apr 7 2026 40804706
Multimodal multicentre investigation of diagnostic and prognostic markers in disorders of consciousness.

Severely brain-injured patients may enter a spectrum of conditions collectively known as disorders of consciousness. This spectrum includes clinical c...

Apr 7 2026 41499248
Interpretable machine learning models for stroke risk prediction in patients with newly diagnosed atrial fibrillation.

Atrial fibrillation (AF) is the most common sustained arrhythmia and a leading cause of ischemic stroke. Existing risk scores, such as CHAâ‚‚DSâ‚‚-VASc, o...

Apr 7 2026 41946928
Quantitative susceptibility mapping and MRS-based multimodal machine learning for early Parkinson's disease classification.

Parkinson's disease (PD) is a complex, progressive neurodegenerative disorder characterized by high heterogeneity and diagnostic challenges in its ear...

Apr 7 2026 41942436
Attention-Enhanced U-Net for Sensor-Efficient High-Density EEG Reconstruction in Wearable Brain Monitoring Systems.

UNLABELLED: High-channel-density (HCD) electroencephalography (EEG) enables fine-grained neural sensing but is constrained by high hardware costs, spa...

Apr 6 2026 41936725
Integrating generative AI and genetic causal inference identifies metformin as a repurposing candidate for normal tension glaucoma.

The normal tension glaucoma (NTG) has limited drug options since current antiglaucoma medications are mostly designed to decrease intraocular pressure...

Apr 6 2026 41943431
Voice Biomarkers: Cognitive Impairment, including Alzheimer's Disease, Dementia, or Mild Cognitive Impairment: Introduction to Peripheral Neuropathy.

INTRODUCTION/OBJECTIVE: Alzheimer's disease (AD) can cause certain nervous disorders, which in turn can lead to voice disorders and abnormal values fo...

Apr 6 2026 41944116
Cost-effectiveness analysis of resective epilepsy surgery in drug-resistant patients: an artificial intelligence data modeling.

BACKGROUND: Resective epilepsy surgery has been proven to reduce the number of seizures and improve quality of life in patients with drug-resistant ep...

Apr 6 2026 41946095
Transcranial Doppler ultrasonography in geriatric anesthesia: moving toward personalized brain protection strategies.

The increasing volume of geriatric surgical procedures presents a critical challenge: protecting the aging brain from perioperative complications such...

Apr 6 2026 41937410
Diagnosis of High Intracranial Pressure by Non-Optic Nerve Retinal Image Features.

PURPOSE: To assess the performance of an artificial intelligence deep learning (DL) model compared with neuro-ophthalmologists for the classification ...

Apr 6 2026 41940708
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