Obstetrics & Gynecology

Latest AI and machine learning research in obstetrics & gynecology for healthcare professionals.

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Showing 3261-3280 of 3,676 articles

Traces of parenthood but not pregnancy loss in UK Biobank structural brain MRI data

Pregnancy induces neuroanatomical changes in the human brain. Earlier studies detected traces of motherhood decades after childbirth. It is unclear whether these reflect persisting traces of pregnancy or effects of parenthood. We investigated effects of past birth and of pregnancy loss in women, and effects of fatherhood in men, using univariate and machine learning analyses on 205 regional brain ...

A transcription factor-responsive enhancer discovery platform for targeted immunotherapy

Synthetic enhancers with high specificity are crucial for therapeutic gene control. Although existing experimental screens and machine learning-based designs have advanced their discovery, these strategies remain context-restricted, typically requiring new cell-type- or state-specific libraries or datasets for each context, thus limiting their generalizability and scalability for broad biomedical ...

Inter- and intra-individual differences in brain sex map to neuroendocrine profiles

Sex hormone fluctuations modulate structural and functional brain dynamics, yet little is known how sex steroid levels map onto the expression of sex ...

Beyond one-size-fits-all: single-cell transcriptomic signatures predict drug efficacy and reveal responder subgroups in endometriosis

Endometriosis affects ∼10% of reproductive-age women, yet targeted non-hormonal therapies remain unavailable, and treatment response is highly variabl...

Biologically Inspired Digital Histology for Deep Phenotyping of Placental Composition Changes Across Major Lesion Types

Placenta pathology provides diagnostic insights for understanding pregnancy complications and guides maternal and perinatal care. While placental abno...

Epigenetic profile drives accurate survival prediction in breast cancer via a multi-omics machine learning model

Accurate overall survival (OS) prediction is key for personalized treatment in breast cancer, but mutation burden alone is insufficient. To improve pr...

Integrative multiomic analysis on single-nucleotide variants identifies candidate genes for human craniofacial malformation

Craniofacial malformation (CFM) is a congenital defect encompassing a wide range of phenotypic presentations and is largely driven by genetics. Despit...

Polli-markers: spectral and chemical biomarkers for detecting cryptic early plant pollination responses

Pollination is essential for plant reproduction, ecosystem resilience and human health. Yet, our capability to map pollination service delivery in rea...

Coxmos: Interpretable survival models for high-dimensional and multi-omic data

Survival analysis in high-dimensional (HD) and multi-block (MB) settings, such as omic and multi-omic studies, poses major methodological challenges d...

Image-Based Profiling of Induced Trophoblast Stem Cells Identifies Signatures Associated with Sex, Schizophrenia Genomic Risk and Placental Stress

Schizophrenia (SCZ) is a neurodevelopmental disorder where both genetic and environmental risks converge during pregnancy. Recent studies have highlig...

Modeling and Design of Multi-layered Cylindrical Microcapsules for Intravitreal Controlled Release

Chronic diseases often require repeated oral or local administration, which can compromise patient compliance. In wet age-related macular degeneration...

Retinal vascularization rate predicts retinopathy of prematurity and remains unaffected by low-dose bevacizumab treatment

To assess the rate of retinal vascularisation derived from ultra-widefield (UWF) imaging-based retinopathy of prematurity (ROP) screening as predictor...

Automatic segmentation of spinal cord lesions in MS: A robust tool for axial T2-weighted MRI scans

Deep learning models have achieved remarkable success in segmenting brain white matter lesions in multiple sclerosis (MS), becoming integral to both r...

Phenotyping Adolescent Endometriosis: Characterizing Symptom Heterogeneity Through Note- and Patient-Level Clustering

Pelvic pain (dysmenorrhea and non-menstrual) is the most common presentation of adolescent endometriosis, but symptoms vary between and within patient...

Assessing the diagnostic accuracy of artificial intelligence in detecting cervical pre-cancer from pap smear images

The global burden of cervical cancer, with a notable prevalence in regions like Tanzania, highlights the critical need for timely and accurate diagnos...

Ovarian cancer recurrence prediction: comparing confirmatory to real world predictors with machine learning

Ovarian cancer is one of the deadliest cancers in women, with a 5-year survival rate of 17-28% in advanced stage (FIGO IIB-IV) disease and is often di...

Benchmarking pathology foundation models for non-neoplastic pathology in the placenta

Machine learning (ML) applications within diagnostic histopathology have been extremely successful. While many successful models have been built using...

Linking physical food outlets to online platforms: A cross-sectional machine learning approach to analysing socioeconomic variations in Great Britain

Physical food outlets are increasingly offering delivery through Online Food Delivery Service (OFDS) platforms, but the scale of this expansion remain...

Deep Learning Study of Alkaptonuria Spinal Disease Assesses Global and Regional Severity and Detects Occult Treatment Status

Deep learning (DL) is increasingly used to analyze medical imaging, but is less refined for rare conditions, which require novel pre-processing and an...

Automated cervix biometry, volumetry and normative models for 3D motion-corrected T2-weighted 0.55-3T fetal MRI during 2nd and 3rd trimesters

Fetal MRI provides superior tissue contrast and true 3D spatial information however there is only a limited number of number of MRI studies investigat...

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